| Full name: SFT2 domain containing 2 | Alias Symbol: UNQ512|dJ747L4.C1.2 | ||
| Type: protein-coding gene | Cytoband: 1q24.2 | ||
| Entrez ID: 375035 | HGNC ID: HGNC:25140 | Ensembl Gene: ENSG00000213064 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SFT2D2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SFT2D2 | 375035 | 225356_at | 0.8164 | 0.0703 | |
| GSE20347 | SFT2D2 | 375035 | 214838_at | -0.9636 | 0.0000 | |
| GSE23400 | SFT2D2 | 375035 | 214838_at | -0.4914 | 0.0000 | |
| GSE26886 | SFT2D2 | 375035 | 225356_at | -1.2280 | 0.0000 | |
| GSE29001 | SFT2D2 | 375035 | 214838_at | -1.3167 | 0.0000 | |
| GSE38129 | SFT2D2 | 375035 | 214838_at | -0.5582 | 0.0056 | |
| GSE45670 | SFT2D2 | 375035 | 225356_at | -0.1567 | 0.2912 | |
| GSE53622 | SFT2D2 | 375035 | 114519 | -0.5398 | 0.0000 | |
| GSE53624 | SFT2D2 | 375035 | 8886 | -1.0154 | 0.0000 | |
| GSE63941 | SFT2D2 | 375035 | 225356_at | -0.6711 | 0.0499 | |
| GSE77861 | SFT2D2 | 375035 | 225356_at | -0.1590 | 0.3515 | |
| GSE97050 | SFT2D2 | 375035 | A_23_P148785 | -0.0732 | 0.8776 | |
| SRP007169 | SFT2D2 | 375035 | RNAseq | -0.7910 | 0.0218 | |
| SRP008496 | SFT2D2 | 375035 | RNAseq | -0.4637 | 0.0325 | |
| SRP064894 | SFT2D2 | 375035 | RNAseq | -0.7334 | 0.0000 | |
| SRP133303 | SFT2D2 | 375035 | RNAseq | -0.2674 | 0.0472 | |
| SRP159526 | SFT2D2 | 375035 | RNAseq | -0.0310 | 0.9206 | |
| SRP193095 | SFT2D2 | 375035 | RNAseq | -0.3481 | 0.0023 | |
| SRP219564 | SFT2D2 | 375035 | RNAseq | -0.2517 | 0.5581 | |
| TCGA | SFT2D2 | 375035 | RNAseq | -0.0158 | 0.8478 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SFT2D2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SFT2D2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFT2D2 | 375035 | 11 | 1 | 18 | |
| GSE20123 | SFT2D2 | 375035 | 11 | 1 | 18 | |
| GSE43470 | SFT2D2 | 375035 | 7 | 2 | 34 | |
| GSE46452 | SFT2D2 | 375035 | 3 | 1 | 55 | |
| GSE47630 | SFT2D2 | 375035 | 14 | 0 | 26 | |
| GSE54993 | SFT2D2 | 375035 | 0 | 6 | 64 | |
| GSE54994 | SFT2D2 | 375035 | 16 | 0 | 37 | |
| GSE60625 | SFT2D2 | 375035 | 0 | 0 | 11 | |
| GSE74703 | SFT2D2 | 375035 | 7 | 2 | 27 | |
| GSE74704 | SFT2D2 | 375035 | 5 | 0 | 15 | |
| TCGA | SFT2D2 | 375035 | 43 | 3 | 50 |
Total number of gains: 117; Total number of losses: 16; Total Number of normals: 355.
Somatic mutations of SFT2D2:
Generating mutation plots.
Highly correlated genes for SFT2D2:
Showing top 20/821 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFT2D2 | CCNG2 | 0.748421 | 10 | 0 | 10 |
| SFT2D2 | KDM1B | 0.740532 | 3 | 0 | 3 |
| SFT2D2 | PLEKHA7 | 0.738837 | 5 | 0 | 5 |
| SFT2D2 | VPS4B | 0.732386 | 11 | 0 | 10 |
| SFT2D2 | TOM1 | 0.72551 | 10 | 0 | 8 |
| SFT2D2 | HOPX | 0.722469 | 9 | 0 | 9 |
| SFT2D2 | GCHFR | 0.720978 | 6 | 0 | 6 |
| SFT2D2 | PRSS3 | 0.720692 | 9 | 0 | 9 |
| SFT2D2 | SH3GL1 | 0.719434 | 10 | 0 | 10 |
| SFT2D2 | MFSD5 | 0.718295 | 11 | 0 | 9 |
| SFT2D2 | PHF6 | 0.717443 | 3 | 0 | 3 |
| SFT2D2 | ACAA1 | 0.71731 | 9 | 0 | 8 |
| SFT2D2 | SMAGP | 0.713239 | 9 | 0 | 8 |
| SFT2D2 | ORMDL2 | 0.712107 | 7 | 0 | 6 |
| SFT2D2 | RANBP9 | 0.709153 | 11 | 0 | 9 |
| SFT2D2 | CYP2J2 | 0.708461 | 9 | 0 | 8 |
| SFT2D2 | NDUFA10 | 0.70803 | 3 | 0 | 3 |
| SFT2D2 | ESPL1 | 0.70733 | 9 | 0 | 8 |
| SFT2D2 | FLG | 0.705367 | 9 | 0 | 8 |
| SFT2D2 | GLTP | 0.703906 | 7 | 0 | 7 |
For details and further investigation, click here
