| Full name: solute carrier family 1 member 4 | Alias Symbol: SATT|ASCT1 | ||
| Type: protein-coding gene | Cytoband: 2p14 | ||
| Entrez ID: 6509 | HGNC ID: HGNC:10942 | Ensembl Gene: ENSG00000115902 | OMIM ID: 600229 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC1A4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC1A4 | 6509 | 209610_s_at | 1.1057 | 0.2886 | |
| GSE20347 | SLC1A4 | 6509 | 212811_x_at | 0.8587 | 0.0071 | |
| GSE23400 | SLC1A4 | 6509 | 212811_x_at | 0.9376 | 0.0000 | |
| GSE26886 | SLC1A4 | 6509 | 209610_s_at | 0.3796 | 0.4824 | |
| GSE29001 | SLC1A4 | 6509 | 212810_s_at | 0.8194 | 0.0481 | |
| GSE38129 | SLC1A4 | 6509 | 212811_x_at | 0.9947 | 0.0001 | |
| GSE45670 | SLC1A4 | 6509 | 209610_s_at | 1.0277 | 0.0014 | |
| GSE53622 | SLC1A4 | 6509 | 40312 | 1.3756 | 0.0000 | |
| GSE53624 | SLC1A4 | 6509 | 40312 | 1.2105 | 0.0000 | |
| GSE63941 | SLC1A4 | 6509 | 212811_x_at | 0.7332 | 0.4323 | |
| GSE77861 | SLC1A4 | 6509 | 212811_x_at | 0.6916 | 0.1578 | |
| GSE97050 | SLC1A4 | 6509 | A_24_P191312 | 0.3843 | 0.1476 | |
| SRP007169 | SLC1A4 | 6509 | RNAseq | 2.4795 | 0.0001 | |
| SRP008496 | SLC1A4 | 6509 | RNAseq | 2.3590 | 0.0000 | |
| SRP064894 | SLC1A4 | 6509 | RNAseq | 1.1360 | 0.0000 | |
| SRP133303 | SLC1A4 | 6509 | RNAseq | 1.2594 | 0.0000 | |
| SRP159526 | SLC1A4 | 6509 | RNAseq | 1.5772 | 0.0006 | |
| SRP193095 | SLC1A4 | 6509 | RNAseq | 1.1857 | 0.0000 | |
| SRP219564 | SLC1A4 | 6509 | RNAseq | 1.3717 | 0.0042 | |
| TCGA | SLC1A4 | 6509 | RNAseq | 0.2932 | 0.0034 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by SLC1A4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC1A4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC1A4 | 6509 | 12 | 0 | 18 | |
| GSE20123 | SLC1A4 | 6509 | 12 | 0 | 18 | |
| GSE43470 | SLC1A4 | 6509 | 6 | 1 | 36 | |
| GSE46452 | SLC1A4 | 6509 | 2 | 3 | 54 | |
| GSE47630 | SLC1A4 | 6509 | 8 | 0 | 32 | |
| GSE54993 | SLC1A4 | 6509 | 0 | 6 | 64 | |
| GSE54994 | SLC1A4 | 6509 | 12 | 2 | 39 | |
| GSE60625 | SLC1A4 | 6509 | 0 | 3 | 8 | |
| GSE74703 | SLC1A4 | 6509 | 6 | 1 | 29 | |
| GSE74704 | SLC1A4 | 6509 | 10 | 0 | 10 | |
| TCGA | SLC1A4 | 6509 | 36 | 2 | 58 |
Total number of gains: 104; Total number of losses: 18; Total Number of normals: 366.
Somatic mutations of SLC1A4:
Generating mutation plots.
Highly correlated genes for SLC1A4:
Showing top 20/402 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC1A4 | ARHGAP22 | 0.694291 | 3 | 0 | 3 |
| SLC1A4 | SPRR2G | 0.670995 | 4 | 0 | 4 |
| SLC1A4 | MTFP1 | 0.661888 | 3 | 0 | 3 |
| SLC1A4 | CDCA5 | 0.660794 | 6 | 0 | 6 |
| SLC1A4 | EML6 | 0.653433 | 5 | 0 | 4 |
| SLC1A4 | DCBLD1 | 0.650594 | 5 | 0 | 4 |
| SLC1A4 | CDK12 | 0.649495 | 3 | 0 | 3 |
| SLC1A4 | CEP19 | 0.649285 | 7 | 0 | 5 |
| SLC1A4 | C2orf81 | 0.647962 | 3 | 0 | 3 |
| SLC1A4 | TNFRSF18 | 0.647465 | 5 | 0 | 5 |
| SLC1A4 | CDC6 | 0.638173 | 7 | 0 | 5 |
| SLC1A4 | TENM2 | 0.635107 | 5 | 0 | 4 |
| SLC1A4 | CKS1B | 0.63318 | 9 | 0 | 9 |
| SLC1A4 | SLCO1A2 | 0.630739 | 3 | 0 | 3 |
| SLC1A4 | SNAI2 | 0.62771 | 9 | 0 | 8 |
| SLC1A4 | TK1 | 0.62725 | 10 | 0 | 10 |
| SLC1A4 | KNSTRN | 0.62571 | 5 | 0 | 5 |
| SLC1A4 | LAMB3 | 0.625211 | 11 | 0 | 9 |
| SLC1A4 | SEC14L4 | 0.623722 | 3 | 0 | 3 |
| SLC1A4 | GPRIN1 | 0.623045 | 4 | 0 | 3 |
For details and further investigation, click here
