| Full name: nucleic acid binding protein 1 | Alias Symbol: FLJ22833|DKFZp667M1322|FLJ13624|MGC111163|SSB2|hSSB2|SOSS-B2 | ||
| Type: protein-coding gene | Cytoband: 2q32.3 | ||
| Entrez ID: 64859 | HGNC ID: HGNC:26232 | Ensembl Gene: ENSG00000173559 | OMIM ID: 612103 |
| Drug and gene relationship at DGIdb | |||
Expression of NABP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NABP1 | 64859 | 222872_x_at | 0.5437 | 0.6174 | |
| GSE20347 | NABP1 | 64859 | 219334_s_at | -0.6033 | 0.0086 | |
| GSE23400 | NABP1 | 64859 | 219334_s_at | -0.2681 | 0.0001 | |
| GSE26886 | NABP1 | 64859 | 222872_x_at | -2.0128 | 0.0000 | |
| GSE29001 | NABP1 | 64859 | 219334_s_at | -1.0543 | 0.0229 | |
| GSE38129 | NABP1 | 64859 | 219334_s_at | -0.2924 | 0.1268 | |
| GSE45670 | NABP1 | 64859 | 222872_x_at | -0.0342 | 0.9314 | |
| GSE53622 | NABP1 | 64859 | 125906 | -0.2847 | 0.0570 | |
| GSE53624 | NABP1 | 64859 | 125906 | -0.7206 | 0.0000 | |
| GSE63941 | NABP1 | 64859 | 222872_x_at | -2.3708 | 0.0100 | |
| GSE77861 | NABP1 | 64859 | 222872_x_at | -0.8920 | 0.0528 | |
| SRP007169 | NABP1 | 64859 | RNAseq | -1.5772 | 0.0042 | |
| SRP008496 | NABP1 | 64859 | RNAseq | -1.6424 | 0.0000 | |
| SRP064894 | NABP1 | 64859 | RNAseq | -1.8885 | 0.0000 | |
| SRP133303 | NABP1 | 64859 | RNAseq | -0.1402 | 0.3861 | |
| SRP159526 | NABP1 | 64859 | RNAseq | -1.2636 | 0.0073 | |
| SRP193095 | NABP1 | 64859 | RNAseq | -0.9903 | 0.0000 | |
| SRP219564 | NABP1 | 64859 | RNAseq | -0.6738 | 0.3142 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by NABP1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of NABP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NABP1 | 64859 | 8 | 2 | 20 | |
| GSE20123 | NABP1 | 64859 | 8 | 2 | 20 | |
| GSE43470 | NABP1 | 64859 | 3 | 1 | 39 | |
| GSE46452 | NABP1 | 64859 | 1 | 4 | 54 | |
| GSE47630 | NABP1 | 64859 | 4 | 5 | 31 | |
| GSE54993 | NABP1 | 64859 | 0 | 5 | 65 | |
| GSE54994 | NABP1 | 64859 | 12 | 6 | 35 | |
| GSE60625 | NABP1 | 64859 | 0 | 3 | 8 | |
| GSE74703 | NABP1 | 64859 | 2 | 1 | 33 | |
| GSE74704 | NABP1 | 64859 | 3 | 2 | 15 | |
| TCGA | NABP1 | 64859 | 25 | 7 | 64 |
Total number of gains: 66; Total number of losses: 38; Total Number of normals: 384.
Somatic mutations of NABP1:
Generating mutation plots.
Highly correlated genes for NABP1:
Showing top 20/493 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NABP1 | SLC31A1 | 0.721695 | 3 | 0 | 3 |
| NABP1 | SPAG1 | 0.680412 | 10 | 0 | 10 |
| NABP1 | EPG5 | 0.676869 | 4 | 0 | 3 |
| NABP1 | SPNS2 | 0.672529 | 3 | 0 | 3 |
| NABP1 | SAMD9L | 0.671307 | 3 | 0 | 3 |
| NABP1 | PLIN3 | 0.670411 | 11 | 0 | 11 |
| NABP1 | ANKHD1 | 0.66492 | 4 | 0 | 4 |
| NABP1 | CLK1 | 0.663633 | 4 | 0 | 4 |
| NABP1 | STXBP5 | 0.657046 | 6 | 0 | 5 |
| NABP1 | RNF149 | 0.655799 | 4 | 0 | 3 |
| NABP1 | ARNTL2 | 0.653546 | 10 | 0 | 9 |
| NABP1 | MXD1 | 0.649117 | 9 | 0 | 9 |
| NABP1 | AKTIP | 0.648779 | 5 | 0 | 4 |
| NABP1 | ZNF101 | 0.647432 | 4 | 0 | 3 |
| NABP1 | IL1A | 0.640055 | 9 | 0 | 7 |
| NABP1 | TMOD3 | 0.639335 | 10 | 0 | 9 |
| NABP1 | ZMYM2 | 0.634909 | 3 | 0 | 3 |
| NABP1 | LGMN | 0.631641 | 3 | 0 | 3 |
| NABP1 | EAF1 | 0.629974 | 4 | 0 | 4 |
| NABP1 | STRADB | 0.628979 | 4 | 0 | 3 |
For details and further investigation, click here
