| Full name: solute carrier family 38 member 2 | Alias Symbol: SAT2|ATA2|KIAA1382|SNAT2 | ||
| Type: protein-coding gene | Cytoband: 12q13.11 | ||
| Entrez ID: 54407 | HGNC ID: HGNC:13448 | Ensembl Gene: ENSG00000134294 | OMIM ID: 605180 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SLC38A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC38A2 | 54407 | 222982_x_at | -0.2391 | 0.5790 | |
| GSE20347 | SLC38A2 | 54407 | 218041_x_at | 0.0753 | 0.7104 | |
| GSE23400 | SLC38A2 | 54407 | 218041_x_at | 0.6355 | 0.0000 | |
| GSE26886 | SLC38A2 | 54407 | 222982_x_at | 0.2086 | 0.3276 | |
| GSE29001 | SLC38A2 | 54407 | 218041_x_at | 0.4317 | 0.2781 | |
| GSE38129 | SLC38A2 | 54407 | 220924_s_at | 0.3542 | 0.0939 | |
| GSE45670 | SLC38A2 | 54407 | 222982_x_at | 0.2040 | 0.1846 | |
| GSE53622 | SLC38A2 | 54407 | 115800 | 0.4443 | 0.0000 | |
| GSE53624 | SLC38A2 | 54407 | 135954 | 0.4623 | 0.0000 | |
| GSE63941 | SLC38A2 | 54407 | 222982_x_at | -1.1912 | 0.0124 | |
| GSE77861 | SLC38A2 | 54407 | 222982_x_at | 0.3231 | 0.2605 | |
| GSE97050 | SLC38A2 | 54407 | A_23_P218079 | 0.5228 | 0.1557 | |
| SRP007169 | SLC38A2 | 54407 | RNAseq | 1.6160 | 0.0047 | |
| SRP008496 | SLC38A2 | 54407 | RNAseq | 0.8694 | 0.0578 | |
| SRP064894 | SLC38A2 | 54407 | RNAseq | 0.2580 | 0.3917 | |
| SRP133303 | SLC38A2 | 54407 | RNAseq | 0.7405 | 0.0040 | |
| SRP159526 | SLC38A2 | 54407 | RNAseq | -0.4882 | 0.0061 | |
| SRP193095 | SLC38A2 | 54407 | RNAseq | 0.1433 | 0.4948 | |
| SRP219564 | SLC38A2 | 54407 | RNAseq | -0.6260 | 0.1098 | |
| TCGA | SLC38A2 | 54407 | RNAseq | 0.0950 | 0.0898 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by SLC38A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC38A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC38A2 | 54407 | 7 | 1 | 22 | |
| GSE20123 | SLC38A2 | 54407 | 7 | 1 | 22 | |
| GSE43470 | SLC38A2 | 54407 | 3 | 1 | 39 | |
| GSE46452 | SLC38A2 | 54407 | 8 | 1 | 50 | |
| GSE47630 | SLC38A2 | 54407 | 11 | 2 | 27 | |
| GSE54993 | SLC38A2 | 54407 | 0 | 5 | 65 | |
| GSE54994 | SLC38A2 | 54407 | 6 | 1 | 46 | |
| GSE60625 | SLC38A2 | 54407 | 0 | 0 | 11 | |
| GSE74703 | SLC38A2 | 54407 | 3 | 1 | 32 | |
| GSE74704 | SLC38A2 | 54407 | 3 | 1 | 16 | |
| TCGA | SLC38A2 | 54407 | 16 | 14 | 66 |
Total number of gains: 64; Total number of losses: 28; Total Number of normals: 396.
Somatic mutations of SLC38A2:
Generating mutation plots.
Highly correlated genes for SLC38A2:
Showing top 20/115 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC38A2 | CYTH3 | 0.64919 | 3 | 0 | 3 |
| SLC38A2 | WDR91 | 0.632104 | 4 | 0 | 3 |
| SLC38A2 | SMIM3 | 0.628427 | 4 | 0 | 3 |
| SLC38A2 | KIF3A | 0.616454 | 3 | 0 | 3 |
| SLC38A2 | PIGW | 0.6128 | 3 | 0 | 3 |
| SLC38A2 | JMY | 0.600533 | 3 | 0 | 3 |
| SLC38A2 | RCOR1 | 0.596208 | 3 | 0 | 3 |
| SLC38A2 | TIAL1 | 0.591951 | 3 | 0 | 3 |
| SLC38A2 | CCDC91 | 0.589903 | 4 | 0 | 3 |
| SLC38A2 | CDK17 | 0.588516 | 5 | 0 | 4 |
| SLC38A2 | STRN3 | 0.586869 | 5 | 0 | 4 |
| SLC38A2 | SLC2A1 | 0.586586 | 8 | 0 | 5 |
| SLC38A2 | PIKFYVE | 0.586352 | 4 | 0 | 3 |
| SLC38A2 | IPO4 | 0.584915 | 3 | 0 | 3 |
| SLC38A2 | ATP6V0D2 | 0.583893 | 4 | 0 | 3 |
| SLC38A2 | JAG1 | 0.582909 | 8 | 0 | 7 |
| SLC38A2 | TWF1 | 0.582607 | 3 | 0 | 3 |
| SLC38A2 | FAM126A | 0.581897 | 6 | 0 | 4 |
| SLC38A2 | PAPPA | 0.577293 | 4 | 0 | 3 |
| SLC38A2 | BDP1 | 0.577084 | 4 | 0 | 3 |
For details and further investigation, click here
