| Full name: solute carrier organic anion transporter family member 4A1 | Alias Symbol: OATP-E|OATP4A1 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 28231 | HGNC ID: HGNC:10953 | Ensembl Gene: ENSG00000101187 | OMIM ID: 612436 |
| Drug and gene relationship at DGIdb | |||
Expression of SLCO4A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLCO4A1 | 28231 | 219911_s_at | -0.0834 | 0.9645 | |
| GSE20347 | SLCO4A1 | 28231 | 219911_s_at | -0.7154 | 0.0409 | |
| GSE23400 | SLCO4A1 | 28231 | 219911_s_at | -0.8631 | 0.0000 | |
| GSE26886 | SLCO4A1 | 28231 | 219911_s_at | -2.3384 | 0.0000 | |
| GSE29001 | SLCO4A1 | 28231 | 219911_s_at | -1.3150 | 0.0155 | |
| GSE38129 | SLCO4A1 | 28231 | 219911_s_at | -0.5153 | 0.0446 | |
| GSE45670 | SLCO4A1 | 28231 | 219911_s_at | -0.1380 | 0.7754 | |
| GSE53622 | SLCO4A1 | 28231 | 151472 | -1.4154 | 0.0000 | |
| GSE53624 | SLCO4A1 | 28231 | 151472 | -1.4706 | 0.0000 | |
| GSE63941 | SLCO4A1 | 28231 | 219911_s_at | 2.0599 | 0.0099 | |
| GSE77861 | SLCO4A1 | 28231 | 219911_s_at | -0.1894 | 0.7203 | |
| SRP007169 | SLCO4A1 | 28231 | RNAseq | -2.3795 | 0.0104 | |
| SRP064894 | SLCO4A1 | 28231 | RNAseq | -1.7356 | 0.0002 | |
| SRP133303 | SLCO4A1 | 28231 | RNAseq | -0.3080 | 0.4172 | |
| SRP159526 | SLCO4A1 | 28231 | RNAseq | -1.1325 | 0.0779 | |
| SRP193095 | SLCO4A1 | 28231 | RNAseq | -0.5767 | 0.0274 | |
| SRP219564 | SLCO4A1 | 28231 | RNAseq | -0.4534 | 0.5020 | |
| TCGA | SLCO4A1 | 28231 | RNAseq | -0.3666 | 0.0707 |
Upregulated datasets: 1; Downregulated datasets: 6.
Survival by SLCO4A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLCO4A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLCO4A1 | 28231 | 14 | 2 | 14 | |
| GSE20123 | SLCO4A1 | 28231 | 14 | 2 | 14 | |
| GSE43470 | SLCO4A1 | 28231 | 11 | 1 | 31 | |
| GSE46452 | SLCO4A1 | 28231 | 35 | 0 | 24 | |
| GSE47630 | SLCO4A1 | 28231 | 25 | 1 | 14 | |
| GSE54993 | SLCO4A1 | 28231 | 0 | 17 | 53 | |
| GSE54994 | SLCO4A1 | 28231 | 29 | 0 | 24 | |
| GSE60625 | SLCO4A1 | 28231 | 0 | 0 | 11 | |
| GSE74703 | SLCO4A1 | 28231 | 10 | 0 | 26 | |
| GSE74704 | SLCO4A1 | 28231 | 11 | 0 | 9 | |
| TCGA | SLCO4A1 | 28231 | 43 | 4 | 49 |
Total number of gains: 192; Total number of losses: 27; Total Number of normals: 269.
Somatic mutations of SLCO4A1:
Generating mutation plots.
Highly correlated genes for SLCO4A1:
Showing top 20/503 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLCO4A1 | C15orf48 | 0.692544 | 3 | 0 | 3 |
| SLCO4A1 | LMNA | 0.686782 | 3 | 0 | 3 |
| SLCO4A1 | FAM3D | 0.68131 | 3 | 0 | 3 |
| SLCO4A1 | DEGS2 | 0.672683 | 3 | 0 | 3 |
| SLCO4A1 | ARHGAP27 | 0.671413 | 4 | 0 | 4 |
| SLCO4A1 | KLB | 0.653461 | 3 | 0 | 3 |
| SLCO4A1 | MAB21L3 | 0.648949 | 3 | 0 | 3 |
| SLCO4A1 | NPEPPS | 0.645824 | 7 | 0 | 6 |
| SLCO4A1 | TGM1 | 0.645288 | 10 | 0 | 8 |
| SLCO4A1 | ATP13A4 | 0.645228 | 3 | 0 | 3 |
| SLCO4A1 | ARNTL2 | 0.639871 | 9 | 0 | 7 |
| SLCO4A1 | PRDM1 | 0.639029 | 9 | 0 | 7 |
| SLCO4A1 | TMPRSS11E | 0.635982 | 8 | 0 | 8 |
| SLCO4A1 | RAB10 | 0.627369 | 4 | 0 | 4 |
| SLCO4A1 | GYS2 | 0.626806 | 7 | 0 | 6 |
| SLCO4A1 | CYSRT1 | 0.626782 | 4 | 0 | 3 |
| SLCO4A1 | DIO2 | 0.623302 | 6 | 0 | 5 |
| SLCO4A1 | MPZL3 | 0.623198 | 6 | 0 | 4 |
| SLCO4A1 | SLC46A2 | 0.622954 | 3 | 0 | 3 |
| SLCO4A1 | ABLIM1 | 0.622729 | 7 | 0 | 5 |
For details and further investigation, click here
