| Full name: small integral membrane protein 12 | Alias Symbol: FLJ90372 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 113444 | HGNC ID: HGNC:25154 | Ensembl Gene: ENSG00000163866 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SMIM12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMIM12 | 113444 | 225404_at | -0.1344 | 0.6933 | |
| GSE26886 | SMIM12 | 113444 | 225404_at | -0.3576 | 0.0581 | |
| GSE45670 | SMIM12 | 113444 | 225404_at | 0.1487 | 0.1820 | |
| GSE53622 | SMIM12 | 113444 | 112470 | -0.2196 | 0.0279 | |
| GSE53624 | SMIM12 | 113444 | 112470 | 0.1291 | 0.1235 | |
| GSE63941 | SMIM12 | 113444 | 225404_at | -0.2718 | 0.3833 | |
| GSE77861 | SMIM12 | 113444 | 225404_at | -0.0575 | 0.7807 | |
| SRP007169 | SMIM12 | 113444 | RNAseq | -0.3263 | 0.4088 | |
| SRP008496 | SMIM12 | 113444 | RNAseq | -0.2600 | 0.2790 | |
| SRP064894 | SMIM12 | 113444 | RNAseq | 0.1949 | 0.3232 | |
| SRP133303 | SMIM12 | 113444 | RNAseq | 0.0318 | 0.7857 | |
| SRP159526 | SMIM12 | 113444 | RNAseq | 0.2826 | 0.5570 | |
| SRP193095 | SMIM12 | 113444 | RNAseq | -0.0743 | 0.3509 | |
| SRP219564 | SMIM12 | 113444 | RNAseq | -0.3417 | 0.2714 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SMIM12 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SMIM12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMIM12 | 113444 | 2 | 5 | 23 | |
| GSE20123 | SMIM12 | 113444 | 2 | 4 | 24 | |
| GSE43470 | SMIM12 | 113444 | 6 | 2 | 35 | |
| GSE46452 | SMIM12 | 113444 | 4 | 1 | 54 | |
| GSE47630 | SMIM12 | 113444 | 8 | 3 | 29 | |
| GSE54993 | SMIM12 | 113444 | 1 | 1 | 68 | |
| GSE54994 | SMIM12 | 113444 | 11 | 2 | 40 | |
| GSE60625 | SMIM12 | 113444 | 0 | 0 | 11 | |
| GSE74703 | SMIM12 | 113444 | 5 | 1 | 30 | |
| GSE74704 | SMIM12 | 113444 | 1 | 0 | 19 | |
| TCGA | SMIM12 | 113444 | 13 | 18 | 65 |
Total number of gains: 53; Total number of losses: 37; Total Number of normals: 398.
Somatic mutations of SMIM12:
Generating mutation plots.
Highly correlated genes for SMIM12:
Showing top 20/76 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMIM12 | UBE2D2 | 0.694465 | 4 | 0 | 4 |
| SMIM12 | HADHA | 0.671438 | 3 | 0 | 3 |
| SMIM12 | CAMLG | 0.653228 | 3 | 0 | 3 |
| SMIM12 | VPS29 | 0.634367 | 3 | 0 | 3 |
| SMIM12 | LRRC42 | 0.617773 | 4 | 0 | 4 |
| SMIM12 | RRAGC | 0.611069 | 3 | 0 | 3 |
| SMIM12 | PSMA5 | 0.60722 | 3 | 0 | 3 |
| SMIM12 | NLRP3 | 0.603345 | 4 | 0 | 4 |
| SMIM12 | MRPL44 | 0.600967 | 5 | 0 | 4 |
| SMIM12 | TRAPPC2L | 0.596543 | 4 | 0 | 3 |
| SMIM12 | PNP | 0.595491 | 3 | 0 | 3 |
| SMIM12 | ADPRHL2 | 0.595466 | 6 | 0 | 5 |
| SMIM12 | SNIP1 | 0.58772 | 6 | 0 | 4 |
| SMIM12 | C1orf122 | 0.587643 | 5 | 0 | 3 |
| SMIM12 | ROBO4 | 0.587424 | 4 | 0 | 4 |
| SMIM12 | DNAJA2 | 0.584637 | 4 | 0 | 3 |
| SMIM12 | CD2BP2 | 0.584269 | 4 | 0 | 3 |
| SMIM12 | SAMM50 | 0.583538 | 3 | 0 | 3 |
| SMIM12 | EIF3I | 0.581403 | 6 | 0 | 5 |
| SMIM12 | SLC5A1 | 0.580989 | 3 | 0 | 3 |
For details and further investigation, click here
