| Full name: castor zinc finger 1 | Alias Symbol: FLJ20321|ZNF693|castor|cst|SRG | ||
| Type: protein-coding gene | Cytoband: 1p36.22 | ||
| Entrez ID: 54897 | HGNC ID: HGNC:26002 | Ensembl Gene: ENSG00000130940 | OMIM ID: 609895 |
| Drug and gene relationship at DGIdb | |||
Expression of CASZ1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CASZ1 | 54897 | 220015_at | -0.1194 | 0.7096 | |
| GSE20347 | CASZ1 | 54897 | 220015_at | -0.1986 | 0.0274 | |
| GSE23400 | CASZ1 | 54897 | 220015_at | -0.1089 | 0.0050 | |
| GSE26886 | CASZ1 | 54897 | 220015_at | -0.2272 | 0.1857 | |
| GSE29001 | CASZ1 | 54897 | 220015_at | -0.1418 | 0.3801 | |
| GSE38129 | CASZ1 | 54897 | 220015_at | -0.1843 | 0.0413 | |
| GSE45670 | CASZ1 | 54897 | 243386_at | 0.0208 | 0.9226 | |
| GSE53622 | CASZ1 | 54897 | 38937 | -0.6967 | 0.0000 | |
| GSE53624 | CASZ1 | 54897 | 38937 | -0.6153 | 0.0000 | |
| GSE63941 | CASZ1 | 54897 | 220015_at | 0.1969 | 0.3920 | |
| GSE77861 | CASZ1 | 54897 | 220015_at | -0.0884 | 0.4048 | |
| GSE97050 | CASZ1 | 54897 | A_23_P201295 | -0.3768 | 0.4882 | |
| SRP007169 | CASZ1 | 54897 | RNAseq | -1.0693 | 0.0442 | |
| SRP008496 | CASZ1 | 54897 | RNAseq | -1.2682 | 0.0001 | |
| SRP064894 | CASZ1 | 54897 | RNAseq | -0.9007 | 0.0002 | |
| SRP133303 | CASZ1 | 54897 | RNAseq | -0.6804 | 0.0000 | |
| SRP159526 | CASZ1 | 54897 | RNAseq | -0.6972 | 0.0019 | |
| SRP193095 | CASZ1 | 54897 | RNAseq | -0.2369 | 0.2653 | |
| SRP219564 | CASZ1 | 54897 | RNAseq | -1.0318 | 0.0084 | |
| TCGA | CASZ1 | 54897 | RNAseq | -0.2446 | 0.0020 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by CASZ1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CASZ1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CASZ1 | 54897 | 0 | 5 | 25 | |
| GSE20123 | CASZ1 | 54897 | 0 | 3 | 27 | |
| GSE43470 | CASZ1 | 54897 | 7 | 5 | 31 | |
| GSE46452 | CASZ1 | 54897 | 7 | 1 | 51 | |
| GSE47630 | CASZ1 | 54897 | 8 | 4 | 28 | |
| GSE54993 | CASZ1 | 54897 | 3 | 1 | 66 | |
| GSE54994 | CASZ1 | 54897 | 11 | 4 | 38 | |
| GSE60625 | CASZ1 | 54897 | 0 | 0 | 11 | |
| GSE74703 | CASZ1 | 54897 | 6 | 3 | 27 | |
| GSE74704 | CASZ1 | 54897 | 0 | 0 | 20 | |
| TCGA | CASZ1 | 54897 | 10 | 25 | 61 |
Total number of gains: 52; Total number of losses: 51; Total Number of normals: 385.
Somatic mutations of CASZ1:
Generating mutation plots.
Highly correlated genes for CASZ1:
Showing top 20/208 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CASZ1 | TSSK1B | 0.656994 | 4 | 0 | 4 |
| CASZ1 | CPEB4 | 0.647722 | 5 | 0 | 4 |
| CASZ1 | SMIM2 | 0.634502 | 3 | 0 | 3 |
| CASZ1 | ATF7 | 0.624171 | 4 | 0 | 4 |
| CASZ1 | SPRR1B | 0.619238 | 3 | 0 | 3 |
| CASZ1 | DAAM1 | 0.616611 | 5 | 0 | 5 |
| CASZ1 | SH3D21 | 0.611077 | 4 | 0 | 3 |
| CASZ1 | PGGT1B | 0.607087 | 5 | 0 | 5 |
| CASZ1 | UMOD | 0.605042 | 4 | 0 | 3 |
| CASZ1 | UBE2E2 | 0.604971 | 4 | 0 | 4 |
| CASZ1 | KLK15 | 0.604469 | 4 | 0 | 3 |
| CASZ1 | UBE4B | 0.599431 | 5 | 0 | 4 |
| CASZ1 | SPPL3 | 0.598345 | 4 | 0 | 3 |
| CASZ1 | CHMP1B | 0.595971 | 3 | 0 | 3 |
| CASZ1 | MVK | 0.593074 | 5 | 0 | 3 |
| CASZ1 | LNX2 | 0.592731 | 4 | 0 | 3 |
| CASZ1 | ESRRB | 0.592093 | 4 | 0 | 3 |
| CASZ1 | RIC3 | 0.590453 | 4 | 0 | 3 |
| CASZ1 | ABLIM2 | 0.589583 | 3 | 0 | 3 |
| CASZ1 | MUC3B | 0.588961 | 3 | 0 | 3 |
For details and further investigation, click here
