| Full name: small integral membrane protein 22 | Alias Symbol: CASIMO1 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 440335 | HGNC ID: HGNC:48329 | Ensembl Gene: ENSG00000267795 | OMIM ID: |
Expression of SMIM22:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMIM22 | 440335 | 229599_at | 0.2455 | 0.7290 | |
| GSE26886 | SMIM22 | 440335 | 229599_at | 0.7232 | 0.0139 | |
| GSE45670 | SMIM22 | 440335 | 229599_at | 0.1340 | 0.6068 | |
| GSE53622 | SMIM22 | 440335 | 12659 | -0.2967 | 0.4335 | |
| GSE53624 | SMIM22 | 440335 | 12659 | -0.5935 | 0.0131 | |
| GSE63941 | SMIM22 | 440335 | 229599_at | 0.8165 | 0.2542 | |
| GSE77861 | SMIM22 | 440335 | 229599_at | -0.2009 | 0.1547 | |
| SRP064894 | SMIM22 | 440335 | RNAseq | -1.7204 | 0.0057 | |
| SRP133303 | SMIM22 | 440335 | RNAseq | 1.1089 | 0.0407 | |
| SRP159526 | SMIM22 | 440335 | RNAseq | 0.4725 | 0.6487 | |
| SRP219564 | SMIM22 | 440335 | RNAseq | -0.8918 | 0.2040 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by SMIM22 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SMIM22:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMIM22 | 440335 | 6 | 5 | 19 | |
| GSE20123 | SMIM22 | 440335 | 6 | 4 | 20 | |
| GSE43470 | SMIM22 | 440335 | 4 | 6 | 33 | |
| GSE46452 | SMIM22 | 440335 | 38 | 1 | 20 | |
| GSE47630 | SMIM22 | 440335 | 13 | 6 | 21 | |
| GSE54993 | SMIM22 | 440335 | 3 | 5 | 62 | |
| GSE54994 | SMIM22 | 440335 | 5 | 9 | 39 | |
| GSE60625 | SMIM22 | 440335 | 4 | 0 | 7 | |
| GSE74703 | SMIM22 | 440335 | 4 | 4 | 28 | |
| GSE74704 | SMIM22 | 440335 | 3 | 2 | 15 | |
| TCGA | SMIM22 | 440335 | 19 | 13 | 64 |
Total number of gains: 105; Total number of losses: 55; Total Number of normals: 328.
Somatic mutations of SMIM22:
Generating mutation plots.
Highly correlated genes for SMIM22:
Showing top 20/21 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMIM22 | CAMTA1 | 0.671408 | 3 | 0 | 3 |
| SMIM22 | PGAP3 | 0.649707 | 3 | 0 | 3 |
| SMIM22 | SH2B1 | 0.623577 | 3 | 0 | 3 |
| SMIM22 | ZNF174 | 0.61981 | 3 | 0 | 3 |
| SMIM22 | TNFSF13 | 0.614418 | 3 | 0 | 3 |
| SMIM22 | MAP1S | 0.610733 | 3 | 0 | 3 |
| SMIM22 | MGAT4A | 0.587805 | 3 | 0 | 3 |
| SMIM22 | SLC44A4 | 0.586307 | 6 | 0 | 5 |
| SMIM22 | MRPL43 | 0.58138 | 3 | 0 | 3 |
| SMIM22 | HRK | 0.581139 | 3 | 0 | 3 |
| SMIM22 | RNF157-AS1 | 0.570543 | 4 | 0 | 3 |
| SMIM22 | TMC5 | 0.562976 | 3 | 0 | 3 |
| SMIM22 | NCOA6 | 0.559688 | 3 | 0 | 3 |
| SMIM22 | C5orf63 | 0.557855 | 4 | 0 | 3 |
| SMIM22 | IP6K2 | 0.549348 | 4 | 0 | 3 |
| SMIM22 | RALGAPA2 | 0.547479 | 5 | 0 | 3 |
| SMIM22 | AGR2 | 0.544786 | 4 | 0 | 3 |
| SMIM22 | RAB40C | 0.544112 | 4 | 0 | 3 |
| SMIM22 | CST2 | 0.535948 | 4 | 0 | 3 |
| SMIM22 | GPR143 | 0.523506 | 4 | 0 | 3 |
For details and further investigation, click here
