| Full name: small nucleolar RNA, H/ACA box 74A | Alias Symbol: U19 | ||
| Type: non-coding RNA | Cytoband: 5q31.2 | ||
| Entrez ID: 26821 | HGNC ID: HGNC:10119 | Ensembl Gene: ENSG00000200959 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SNORA74A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNORA74A | 26821 | 1567681_at | -0.0822 | 0.7963 | |
| GSE26886 | SNORA74A | 26821 | 1567681_at | -0.1053 | 0.4076 | |
| GSE45670 | SNORA74A | 26821 | 1567679_at | -0.1300 | 0.1650 | |
| GSE63941 | SNORA74A | 26821 | 1567681_at | 0.2160 | 0.3204 | |
| GSE77861 | SNORA74A | 26821 | 1567681_at | -0.1257 | 0.3285 | |
| SRP007169 | SNORA74A | 26821 | RNAseq | -2.6780 | 0.0001 | |
| SRP008496 | SNORA74A | 26821 | RNAseq | -1.6172 | 0.0018 | |
| SRP133303 | SNORA74A | 26821 | RNAseq | -0.8720 | 0.0151 | |
| SRP193095 | SNORA74A | 26821 | RNAseq | -1.9472 | 0.0000 | |
| TCGA | SNORA74A | 26821 | RNAseq | 0.7829 | 0.4157 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SNORA74A expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SNORA74A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNORA74A | 26821 | 3 | 11 | 16 | |
| GSE20123 | SNORA74A | 26821 | 4 | 11 | 15 | |
| GSE43470 | SNORA74A | 26821 | 4 | 7 | 32 | |
| GSE46452 | SNORA74A | 26821 | 0 | 27 | 32 | |
| GSE47630 | SNORA74A | 26821 | 0 | 21 | 19 | |
| GSE54993 | SNORA74A | 26821 | 9 | 1 | 60 | |
| GSE54994 | SNORA74A | 26821 | 2 | 15 | 36 | |
| GSE60625 | SNORA74A | 26821 | 0 | 0 | 11 | |
| GSE74703 | SNORA74A | 26821 | 3 | 5 | 28 | |
| GSE74704 | SNORA74A | 26821 | 3 | 5 | 12 | |
| TCGA | SNORA74A | 26821 | 4 | 37 | 55 |
Total number of gains: 32; Total number of losses: 140; Total Number of normals: 316.
Somatic mutations of SNORA74A:
Generating mutation plots.
Highly correlated genes for SNORA74A:
Showing all 20 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNORA74A | HUS1B | 0.622537 | 3 | 0 | 3 |
| SNORA74A | ANKRD44-IT1 | 0.613204 | 3 | 0 | 3 |
| SNORA74A | DPEP3 | 0.608071 | 4 | 0 | 3 |
| SNORA74A | LRRC29 | 0.597623 | 3 | 0 | 3 |
| SNORA74A | OPCML | 0.583185 | 3 | 0 | 3 |
| SNORA74A | ZNF135 | 0.566194 | 4 | 0 | 4 |
| SNORA74A | AIPL1 | 0.566058 | 3 | 0 | 3 |
| SNORA74A | FGF22 | 0.559774 | 4 | 0 | 3 |
| SNORA74A | NODAL | 0.559285 | 4 | 0 | 3 |
| SNORA74A | PPEF2 | 0.558047 | 3 | 0 | 3 |
| SNORA74A | MYLK2 | 0.554544 | 4 | 0 | 3 |
| SNORA74A | AKNAD1 | 0.549484 | 4 | 0 | 3 |
| SNORA74A | VRTN | 0.549351 | 3 | 0 | 3 |
| SNORA74A | GPT | 0.544084 | 4 | 0 | 3 |
| SNORA74A | TRPC5 | 0.538725 | 4 | 0 | 3 |
| SNORA74A | ARMC12 | 0.536347 | 3 | 0 | 3 |
| SNORA74A | ZAR1 | 0.521685 | 3 | 0 | 3 |
| SNORA74A | SPATA3-AS1 | 0.519375 | 3 | 0 | 3 |
| SNORA74A | PRR29 | 0.519359 | 4 | 0 | 3 |
| SNORA74A | ZNF541 | 0.502186 | 5 | 0 | 3 |
For details and further investigation, click here
