| Full name: serine peptidase inhibitor, Kazal type 13 (putative) | Alias Symbol: SPINK5L3|LiESP6|HESPINTOR|MGC149260 | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 153218 | HGNC ID: HGNC:27200 | Ensembl Gene: ENSG00000214510 | OMIM ID: 615205 |
| Drug and gene relationship at DGIdb | |||
Expression of SPINK13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPINK13 | 153218 | 233340_at | -0.1371 | 0.6141 | |
| GSE26886 | SPINK13 | 153218 | 233340_at | 0.0196 | 0.8255 | |
| GSE45670 | SPINK13 | 153218 | 233340_at | 0.1505 | 0.0586 | |
| GSE53622 | SPINK13 | 153218 | 31394 | -1.1014 | 0.0000 | |
| GSE53624 | SPINK13 | 153218 | 31394 | -1.5381 | 0.0000 | |
| GSE63941 | SPINK13 | 153218 | 233340_at | 0.2547 | 0.3458 | |
| GSE77861 | SPINK13 | 153218 | 233340_at | -0.1225 | 0.2285 | |
| TCGA | SPINK13 | 153218 | RNAseq | -4.6617 | 0.0301 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SPINK13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPINK13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPINK13 | 153218 | 1 | 12 | 17 | |
| GSE20123 | SPINK13 | 153218 | 1 | 13 | 16 | |
| GSE43470 | SPINK13 | 153218 | 2 | 9 | 32 | |
| GSE46452 | SPINK13 | 153218 | 0 | 27 | 32 | |
| GSE47630 | SPINK13 | 153218 | 0 | 20 | 20 | |
| GSE54993 | SPINK13 | 153218 | 9 | 1 | 60 | |
| GSE54994 | SPINK13 | 153218 | 2 | 15 | 36 | |
| GSE60625 | SPINK13 | 153218 | 0 | 0 | 11 | |
| GSE74703 | SPINK13 | 153218 | 2 | 7 | 27 | |
| GSE74704 | SPINK13 | 153218 | 1 | 8 | 11 | |
| TCGA | SPINK13 | 153218 | 5 | 38 | 53 |
Total number of gains: 23; Total number of losses: 150; Total Number of normals: 315.
Somatic mutations of SPINK13:
Generating mutation plots.
Highly correlated genes for SPINK13:
Showing top 20/211 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPINK13 | ATRNL1 | 0.78638 | 3 | 0 | 3 |
| SPINK13 | GYS2 | 0.725368 | 3 | 0 | 3 |
| SPINK13 | YOD1 | 0.718956 | 3 | 0 | 3 |
| SPINK13 | UPK1A | 0.71585 | 3 | 0 | 3 |
| SPINK13 | MXD1 | 0.714637 | 3 | 0 | 3 |
| SPINK13 | C1orf116 | 0.711298 | 3 | 0 | 3 |
| SPINK13 | FNDC4 | 0.709057 | 3 | 0 | 3 |
| SPINK13 | PTK6 | 0.706715 | 3 | 0 | 3 |
| SPINK13 | IL2 | 0.704928 | 3 | 0 | 3 |
| SPINK13 | NCR1 | 0.704711 | 4 | 0 | 3 |
| SPINK13 | C3orf20 | 0.704419 | 3 | 0 | 3 |
| SPINK13 | UBL3 | 0.704318 | 3 | 0 | 3 |
| SPINK13 | S100A14 | 0.703 | 3 | 0 | 3 |
| SPINK13 | KRT78 | 0.698209 | 3 | 0 | 3 |
| SPINK13 | ARID5A | 0.695994 | 3 | 0 | 3 |
| SPINK13 | SFRP5 | 0.695223 | 3 | 0 | 3 |
| SPINK13 | NAPA | 0.693614 | 3 | 0 | 3 |
| SPINK13 | APOA1 | 0.692682 | 4 | 0 | 3 |
| SPINK13 | AIF1L | 0.692438 | 3 | 0 | 3 |
| SPINK13 | ZNF365 | 0.689039 | 3 | 0 | 3 |
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