| Full name: SPRY domain containing 7 | Alias Symbol: CLLD6 | ||
| Type: protein-coding gene | Cytoband: 13q14.2 | ||
| Entrez ID: 57213 | HGNC ID: HGNC:14297 | Ensembl Gene: ENSG00000123178 | OMIM ID: 607866 |
| Drug and gene relationship at DGIdb | |||
Expression of SPRYD7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPRYD7 | 57213 | 230151_at | -0.5468 | 0.2565 | |
| GSE20347 | SPRYD7 | 57213 | 214668_at | -0.6444 | 0.0000 | |
| GSE23400 | SPRYD7 | 57213 | 214668_at | -0.0981 | 0.0019 | |
| GSE26886 | SPRYD7 | 57213 | 230151_at | -0.1602 | 0.6460 | |
| GSE29001 | SPRYD7 | 57213 | 214668_at | -0.2994 | 0.1367 | |
| GSE38129 | SPRYD7 | 57213 | 214668_at | -0.5117 | 0.0013 | |
| GSE45670 | SPRYD7 | 57213 | 230151_at | -0.4474 | 0.0066 | |
| GSE53622 | SPRYD7 | 57213 | 81809 | -0.7867 | 0.0000 | |
| GSE53624 | SPRYD7 | 57213 | 81809 | -0.6646 | 0.0000 | |
| GSE63941 | SPRYD7 | 57213 | 230151_at | -0.5107 | 0.2951 | |
| GSE77861 | SPRYD7 | 57213 | 230151_at | -0.3517 | 0.0879 | |
| SRP007169 | SPRYD7 | 57213 | RNAseq | -0.4869 | 0.3753 | |
| SRP008496 | SPRYD7 | 57213 | RNAseq | -0.4521 | 0.1984 | |
| SRP064894 | SPRYD7 | 57213 | RNAseq | -0.2203 | 0.1694 | |
| SRP133303 | SPRYD7 | 57213 | RNAseq | -0.3006 | 0.0551 | |
| SRP159526 | SPRYD7 | 57213 | RNAseq | -0.6886 | 0.0608 | |
| SRP193095 | SPRYD7 | 57213 | RNAseq | -0.3571 | 0.0072 | |
| SRP219564 | SPRYD7 | 57213 | RNAseq | -0.5930 | 0.0161 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPRYD7 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SPRYD7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPRYD7 | 57213 | 1 | 13 | 16 | |
| GSE20123 | SPRYD7 | 57213 | 1 | 12 | 17 | |
| GSE43470 | SPRYD7 | 57213 | 3 | 13 | 27 | |
| GSE46452 | SPRYD7 | 57213 | 0 | 32 | 27 | |
| GSE47630 | SPRYD7 | 57213 | 2 | 27 | 11 | |
| GSE54993 | SPRYD7 | 57213 | 12 | 2 | 56 | |
| GSE54994 | SPRYD7 | 57213 | 2 | 14 | 37 | |
| GSE60625 | SPRYD7 | 57213 | 0 | 3 | 8 | |
| GSE74703 | SPRYD7 | 57213 | 3 | 10 | 23 | |
| GSE74704 | SPRYD7 | 57213 | 0 | 9 | 11 | |
| TCGA | SPRYD7 | 57213 | 9 | 37 | 50 |
Total number of gains: 33; Total number of losses: 172; Total Number of normals: 283.
Somatic mutations of SPRYD7:
Generating mutation plots.
Highly correlated genes for SPRYD7:
Showing top 20/431 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPRYD7 | ELL2 | 0.65011 | 6 | 0 | 6 |
| SPRYD7 | THOC7 | 0.645017 | 7 | 0 | 6 |
| SPRYD7 | MRPS36 | 0.630185 | 6 | 0 | 5 |
| SPRYD7 | EIF3M | 0.623736 | 3 | 0 | 3 |
| SPRYD7 | YTHDC2 | 0.623426 | 6 | 0 | 5 |
| SPRYD7 | GPR12 | 0.619157 | 4 | 0 | 4 |
| SPRYD7 | SREK1IP1 | 0.616928 | 8 | 0 | 7 |
| SPRYD7 | UBL5 | 0.616374 | 4 | 0 | 4 |
| SPRYD7 | WDFY2 | 0.607908 | 6 | 0 | 5 |
| SPRYD7 | CRYL1 | 0.607821 | 8 | 0 | 7 |
| SPRYD7 | SERPINI2 | 0.607242 | 3 | 0 | 3 |
| SPRYD7 | GALR3 | 0.606634 | 5 | 0 | 4 |
| SPRYD7 | ATP6V1G1 | 0.606228 | 4 | 0 | 3 |
| SPRYD7 | MTIF3 | 0.601346 | 6 | 0 | 4 |
| SPRYD7 | RAB14 | 0.600406 | 7 | 0 | 5 |
| SPRYD7 | USP25 | 0.599717 | 7 | 0 | 5 |
| SPRYD7 | AIFM2 | 0.598425 | 3 | 0 | 3 |
| SPRYD7 | AHNAK | 0.596246 | 5 | 0 | 4 |
| SPRYD7 | PRDM1 | 0.596127 | 5 | 0 | 5 |
| SPRYD7 | ACAA1 | 0.595447 | 5 | 0 | 4 |
For details and further investigation, click here
