| Full name: WD repeat and FYVE domain containing 2 | Alias Symbol: ZFYVE22 | ||
| Type: protein-coding gene | Cytoband: 13q14.3 | ||
| Entrez ID: 115825 | HGNC ID: HGNC:20482 | Ensembl Gene: ENSG00000139668 | OMIM ID: 610418 |
| Drug and gene relationship at DGIdb | |||
Expression of WDFY2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDFY2 | 115825 | 228159_at | -0.3358 | 0.2180 | |
| GSE26886 | WDFY2 | 115825 | 228159_at | -0.4675 | 0.0228 | |
| GSE45670 | WDFY2 | 115825 | 228159_at | -0.2541 | 0.0967 | |
| GSE53622 | WDFY2 | 115825 | 50588 | -0.8341 | 0.0000 | |
| GSE53624 | WDFY2 | 115825 | 50588 | -0.8564 | 0.0000 | |
| GSE63941 | WDFY2 | 115825 | 228159_at | 0.4576 | 0.3126 | |
| GSE77861 | WDFY2 | 115825 | 228159_at | -0.0232 | 0.9458 | |
| GSE97050 | WDFY2 | 115825 | A_33_P3209646 | -0.2651 | 0.3925 | |
| SRP007169 | WDFY2 | 115825 | RNAseq | -1.0072 | 0.0286 | |
| SRP008496 | WDFY2 | 115825 | RNAseq | -0.6998 | 0.0551 | |
| SRP064894 | WDFY2 | 115825 | RNAseq | -0.3229 | 0.1510 | |
| SRP133303 | WDFY2 | 115825 | RNAseq | -0.4636 | 0.0668 | |
| SRP159526 | WDFY2 | 115825 | RNAseq | -0.8840 | 0.0085 | |
| SRP193095 | WDFY2 | 115825 | RNAseq | -0.4915 | 0.0167 | |
| SRP219564 | WDFY2 | 115825 | RNAseq | -0.5142 | 0.3497 | |
| TCGA | WDFY2 | 115825 | RNAseq | -0.0501 | 0.4784 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by WDFY2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDFY2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDFY2 | 115825 | 1 | 12 | 17 | |
| GSE20123 | WDFY2 | 115825 | 1 | 11 | 18 | |
| GSE43470 | WDFY2 | 115825 | 3 | 12 | 28 | |
| GSE46452 | WDFY2 | 115825 | 0 | 32 | 27 | |
| GSE47630 | WDFY2 | 115825 | 2 | 27 | 11 | |
| GSE54993 | WDFY2 | 115825 | 12 | 2 | 56 | |
| GSE54994 | WDFY2 | 115825 | 1 | 15 | 37 | |
| GSE60625 | WDFY2 | 115825 | 0 | 3 | 8 | |
| GSE74703 | WDFY2 | 115825 | 3 | 10 | 23 | |
| GSE74704 | WDFY2 | 115825 | 0 | 8 | 12 | |
| TCGA | WDFY2 | 115825 | 9 | 36 | 51 |
Total number of gains: 32; Total number of losses: 168; Total Number of normals: 288.
Somatic mutations of WDFY2:
Generating mutation plots.
Highly correlated genes for WDFY2:
Showing top 20/807 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDFY2 | STAM2 | 0.750841 | 3 | 0 | 3 |
| WDFY2 | HEMK1 | 0.730201 | 3 | 0 | 3 |
| WDFY2 | PGM2 | 0.727473 | 4 | 0 | 4 |
| WDFY2 | ZMYM2 | 0.713562 | 4 | 0 | 4 |
| WDFY2 | CYSRT1 | 0.711376 | 4 | 0 | 4 |
| WDFY2 | HUS1 | 0.710271 | 3 | 0 | 3 |
| WDFY2 | MYL12B | 0.703431 | 3 | 0 | 3 |
| WDFY2 | MLIP | 0.701898 | 4 | 0 | 4 |
| WDFY2 | UBE2E1 | 0.698981 | 4 | 0 | 3 |
| WDFY2 | YOD1 | 0.697678 | 5 | 0 | 5 |
| WDFY2 | EPGN | 0.697498 | 3 | 0 | 3 |
| WDFY2 | ENOSF1 | 0.694352 | 3 | 0 | 3 |
| WDFY2 | ARF5 | 0.69315 | 3 | 0 | 3 |
| WDFY2 | MPZL3 | 0.692633 | 5 | 0 | 5 |
| WDFY2 | NDUFC1 | 0.689837 | 3 | 0 | 3 |
| WDFY2 | NQO1 | 0.68983 | 3 | 0 | 3 |
| WDFY2 | TWF1 | 0.689636 | 5 | 0 | 5 |
| WDFY2 | TOM1 | 0.689597 | 6 | 0 | 5 |
| WDFY2 | SCP2 | 0.688703 | 4 | 0 | 4 |
| WDFY2 | TECR | 0.687125 | 4 | 0 | 3 |
For details and further investigation, click here
