| Full name: somatostatin receptor 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q13 | ||
| Entrez ID: 6751 | HGNC ID: HGNC:11330 | Ensembl Gene: ENSG00000139874 | OMIM ID: 182451 |
| Drug and gene relationship at DGIdb | |||
SSTR1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04024 | cAMP signaling pathway |
Expression of SSTR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SSTR1 | 6751 | 208482_at | 0.2140 | 0.3965 | |
| GSE20347 | SSTR1 | 6751 | 208482_at | -0.0540 | 0.4540 | |
| GSE23400 | SSTR1 | 6751 | 208482_at | -0.0777 | 0.0280 | |
| GSE26886 | SSTR1 | 6751 | 208482_at | 0.1645 | 0.1293 | |
| GSE29001 | SSTR1 | 6751 | 208482_at | -0.0431 | 0.7404 | |
| GSE38129 | SSTR1 | 6751 | 208482_at | -0.0554 | 0.4059 | |
| GSE45670 | SSTR1 | 6751 | 208482_at | -0.0460 | 0.6552 | |
| GSE53622 | SSTR1 | 6751 | 44577 | 0.0859 | 0.4429 | |
| GSE53624 | SSTR1 | 6751 | 44577 | 0.0501 | 0.5790 | |
| GSE63941 | SSTR1 | 6751 | 208482_at | -0.2699 | 0.0751 | |
| GSE77861 | SSTR1 | 6751 | 208482_at | -0.0067 | 0.9620 | |
| SRP133303 | SSTR1 | 6751 | RNAseq | -3.7305 | 0.0000 | |
| TCGA | SSTR1 | 6751 | RNAseq | -4.0077 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SSTR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SSTR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SSTR1 | 6751 | 11 | 4 | 15 | |
| GSE20123 | SSTR1 | 6751 | 11 | 4 | 15 | |
| GSE43470 | SSTR1 | 6751 | 8 | 3 | 32 | |
| GSE46452 | SSTR1 | 6751 | 18 | 2 | 39 | |
| GSE47630 | SSTR1 | 6751 | 11 | 10 | 19 | |
| GSE54993 | SSTR1 | 6751 | 3 | 9 | 58 | |
| GSE54994 | SSTR1 | 6751 | 19 | 5 | 29 | |
| GSE60625 | SSTR1 | 6751 | 0 | 2 | 9 | |
| GSE74703 | SSTR1 | 6751 | 7 | 3 | 26 | |
| GSE74704 | SSTR1 | 6751 | 5 | 3 | 12 | |
| TCGA | SSTR1 | 6751 | 34 | 14 | 48 |
Total number of gains: 127; Total number of losses: 59; Total Number of normals: 302.
Somatic mutations of SSTR1:
Generating mutation plots.
Highly correlated genes for SSTR1:
Showing top 20/88 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SSTR1 | KRT35 | 0.692416 | 3 | 0 | 3 |
| SSTR1 | RFPL2 | 0.687956 | 3 | 0 | 3 |
| SSTR1 | HAPLN1 | 0.6718 | 4 | 0 | 3 |
| SSTR1 | IL19 | 0.646749 | 3 | 0 | 3 |
| SSTR1 | SERINC2 | 0.642977 | 3 | 0 | 3 |
| SSTR1 | CHPF | 0.63875 | 3 | 0 | 3 |
| SSTR1 | NMNAT2 | 0.637956 | 3 | 0 | 3 |
| SSTR1 | TREML2 | 0.619678 | 3 | 0 | 3 |
| SSTR1 | ALOXE3 | 0.61836 | 3 | 0 | 3 |
| SSTR1 | AZU1 | 0.618344 | 3 | 0 | 3 |
| SSTR1 | LINC00574 | 0.617656 | 3 | 0 | 3 |
| SSTR1 | PIWIL2 | 0.61644 | 4 | 0 | 4 |
| SSTR1 | COLEC10 | 0.608459 | 3 | 0 | 3 |
| SSTR1 | KCNK13 | 0.605049 | 4 | 0 | 3 |
| SSTR1 | FOLR3 | 0.604201 | 3 | 0 | 3 |
| SSTR1 | C16orf87 | 0.599053 | 3 | 0 | 3 |
| SSTR1 | GFM1 | 0.597108 | 3 | 0 | 3 |
| SSTR1 | CPA2 | 0.596992 | 5 | 0 | 3 |
| SSTR1 | MSH4 | 0.596476 | 4 | 0 | 3 |
| SSTR1 | CYP17A1 | 0.596438 | 4 | 0 | 3 |
For details and further investigation, click here
