STAB1

 

Full name: stabilin 1 Alias Symbol: KIAA0246|STAB-1|FEEL-1|CLEVER-1|FELE-1|FEX1|SCARH2
Type: protein-coding gene Cytoband: 3p21.1
Entrez ID: 23166 HGNC ID: HGNC:18628 Ensembl Gene: ENSG00000010327 OMIM ID: 608560
Drug and gene relationship at DGIdb

 

Expression of STAB1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 STAB1 23166 38487_at -0.1810 0.7615
GSE20347 STAB1 23166 38487_at 0.0884 0.5526
GSE23400 STAB1 23166 38487_at -0.0837 0.3791
GSE26886 STAB1 23166 38487_at 0.1467 0.4328
GSE29001 STAB1 23166 38487_at -0.0114 0.9682
GSE38129 STAB1 23166 38487_at -0.1412 0.5371
GSE45670 STAB1 23166 38487_at -0.3248 0.0766
GSE53622 STAB1 23166 28777 -0.3221 0.0126
GSE53624 STAB1 23166 28777 0.0017 0.9916
GSE63941 STAB1 23166 38487_at 0.3526 0.0026
GSE77861 STAB1 23166 38487_at 0.1142 0.5788
GSE97050 STAB1 23166 A_23_P32500 0.4903 0.2796
SRP007169 STAB1 23166 RNAseq 1.0960 0.0342
SRP008496 STAB1 23166 RNAseq 1.0452 0.0046
SRP064894 STAB1 23166 RNAseq 0.2691 0.3701
SRP133303 STAB1 23166 RNAseq -0.2652 0.4582
SRP159526 STAB1 23166 RNAseq -0.1640 0.6705
SRP193095 STAB1 23166 RNAseq 0.5401 0.0501
SRP219564 STAB1 23166 RNAseq 0.6467 0.3229
TCGA STAB1 23166 RNAseq -0.2237 0.0267

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by STAB1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of STAB1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 STAB1 23166 0 18 12
GSE20123 STAB1 23166 0 19 11
GSE43470 STAB1 23166 0 18 25
GSE46452 STAB1 23166 2 17 40
GSE47630 STAB1 23166 1 24 15
GSE54993 STAB1 23166 6 2 62
GSE54994 STAB1 23166 0 33 20
GSE60625 STAB1 23166 5 0 6
GSE74703 STAB1 23166 0 14 22
GSE74704 STAB1 23166 0 12 8
TCGA STAB1 23166 0 78 18

Total number of gains: 14; Total number of losses: 235; Total Number of normals: 239.  


 

Somatic mutations of STAB1:

 

Generating mutation plots.

 

Highly correlated genes for STAB1:

 

Showing top 20/417 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
STAB1RBP50.763041303
STAB1C19orf380.755099303
STAB1GIMAP50.752402404
STAB1MPEG10.751614606
STAB1GIMAP70.736704606
STAB1CR1L0.723647403
STAB1GIMAP10.722149605
STAB1TIE10.706051807
STAB1CSF1R0.70157711010
STAB1C30.7001251009
STAB1ANGPTL60.697478403
STAB1SIGLEC10.69324810010
STAB1PREX10.691179504
STAB1TNFSF120.689875303
STAB1C1orf1620.689275706
STAB1NAIP0.685994404
STAB1C1QA0.6844541109
STAB1NAA110.68264303
STAB1FBXO60.679975303
STAB1RASAL30.677874404

For details and further investigation, click here