| Full name: serine/threonine kinase 17b | Alias Symbol: DRAK2 | ||
| Type: protein-coding gene | Cytoband: 2q32.3 | ||
| Entrez ID: 9262 | HGNC ID: HGNC:11396 | Ensembl Gene: ENSG00000081320 | OMIM ID: 604727 |
| Drug and gene relationship at DGIdb | |||
Expression of STK17B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STK17B | 9262 | 226525_at | 0.5623 | 0.4389 | |
| GSE20347 | STK17B | 9262 | 205214_at | 0.4420 | 0.0195 | |
| GSE23400 | STK17B | 9262 | 205214_at | 0.3616 | 0.0000 | |
| GSE26886 | STK17B | 9262 | 226525_at | -0.0188 | 0.9595 | |
| GSE29001 | STK17B | 9262 | 205214_at | 0.3762 | 0.0369 | |
| GSE38129 | STK17B | 9262 | 205214_at | 0.7385 | 0.0042 | |
| GSE45670 | STK17B | 9262 | 226525_at | -0.0305 | 0.9207 | |
| GSE53622 | STK17B | 9262 | 71331 | 0.4331 | 0.0000 | |
| GSE53624 | STK17B | 9262 | 71331 | 0.5502 | 0.0000 | |
| GSE63941 | STK17B | 9262 | 226525_at | 0.0018 | 0.9985 | |
| GSE77861 | STK17B | 9262 | 226525_at | 0.5432 | 0.1067 | |
| GSE97050 | STK17B | 9262 | A_33_P3342957 | 1.2201 | 0.1073 | |
| SRP007169 | STK17B | 9262 | RNAseq | 0.4843 | 0.2251 | |
| SRP008496 | STK17B | 9262 | RNAseq | 0.7944 | 0.0035 | |
| SRP064894 | STK17B | 9262 | RNAseq | 0.3797 | 0.1680 | |
| SRP133303 | STK17B | 9262 | RNAseq | 0.5749 | 0.0218 | |
| SRP159526 | STK17B | 9262 | RNAseq | -0.4563 | 0.3631 | |
| SRP193095 | STK17B | 9262 | RNAseq | 0.1931 | 0.3858 | |
| SRP219564 | STK17B | 9262 | RNAseq | 0.6813 | 0.1619 | |
| TCGA | STK17B | 9262 | RNAseq | 0.0647 | 0.3727 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STK17B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STK17B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STK17B | 9262 | 8 | 2 | 20 | |
| GSE20123 | STK17B | 9262 | 8 | 2 | 20 | |
| GSE43470 | STK17B | 9262 | 3 | 1 | 39 | |
| GSE46452 | STK17B | 9262 | 1 | 4 | 54 | |
| GSE47630 | STK17B | 9262 | 4 | 5 | 31 | |
| GSE54993 | STK17B | 9262 | 0 | 4 | 66 | |
| GSE54994 | STK17B | 9262 | 11 | 7 | 35 | |
| GSE60625 | STK17B | 9262 | 0 | 3 | 8 | |
| GSE74703 | STK17B | 9262 | 2 | 1 | 33 | |
| GSE74704 | STK17B | 9262 | 3 | 2 | 15 | |
| TCGA | STK17B | 9262 | 22 | 9 | 65 |
Total number of gains: 62; Total number of losses: 40; Total Number of normals: 386.
Somatic mutations of STK17B:
Generating mutation plots.
Highly correlated genes for STK17B:
Showing top 20/669 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STK17B | TCF19 | 0.747195 | 3 | 0 | 3 |
| STK17B | FAM107B | 0.728853 | 3 | 0 | 3 |
| STK17B | SLC30A7 | 0.721916 | 5 | 0 | 5 |
| STK17B | PHTF1 | 0.706588 | 4 | 0 | 4 |
| STK17B | KLHL6 | 0.697142 | 5 | 0 | 5 |
| STK17B | IL2RG | 0.696631 | 4 | 0 | 4 |
| STK17B | RB1 | 0.69619 | 3 | 0 | 3 |
| STK17B | GINS3 | 0.691279 | 3 | 0 | 3 |
| STK17B | CYBA | 0.687362 | 6 | 0 | 5 |
| STK17B | C16orf54 | 0.681593 | 5 | 0 | 4 |
| STK17B | PIK3AP1 | 0.680883 | 5 | 0 | 4 |
| STK17B | PLEKHA2 | 0.679921 | 3 | 0 | 3 |
| STK17B | FANCM | 0.66923 | 3 | 0 | 3 |
| STK17B | PDCD1LG2 | 0.666575 | 3 | 0 | 3 |
| STK17B | XPO5 | 0.666065 | 3 | 0 | 3 |
| STK17B | BNC1 | 0.665455 | 5 | 0 | 4 |
| STK17B | AGTPBP1 | 0.660654 | 4 | 0 | 4 |
| STK17B | IKBIP | 0.660488 | 5 | 0 | 5 |
| STK17B | P2RY8 | 0.660381 | 4 | 0 | 3 |
| STK17B | CDC42EP1 | 0.659725 | 3 | 0 | 3 |
For details and further investigation, click here
