| Full name: short chain dehydrogenase/reductase family 16C member 5 | Alias Symbol: RDHE2|RDH-E2|EPHD-2 | ||
| Type: protein-coding gene | Cytoband: 8q12.1 | ||
| Entrez ID: 195814 | HGNC ID: HGNC:30311 | Ensembl Gene: ENSG00000170786 | OMIM ID: 608989 |
| Drug and gene relationship at DGIdb | |||
Expression of SDR16C5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SDR16C5 | 195814 | 238017_at | -1.7387 | 0.3463 | |
| GSE26886 | SDR16C5 | 195814 | 238017_at | -3.5295 | 0.0000 | |
| GSE45670 | SDR16C5 | 195814 | 238017_at | 0.0172 | 0.9645 | |
| GSE53622 | SDR16C5 | 195814 | 62028 | -1.7953 | 0.0000 | |
| GSE53624 | SDR16C5 | 195814 | 62028 | -2.1183 | 0.0000 | |
| GSE63941 | SDR16C5 | 195814 | 238017_at | 1.9167 | 0.2941 | |
| GSE77861 | SDR16C5 | 195814 | 238017_at | -1.2096 | 0.0580 | |
| SRP007169 | SDR16C5 | 195814 | RNAseq | -2.9977 | 0.0000 | |
| SRP008496 | SDR16C5 | 195814 | RNAseq | -3.2660 | 0.0000 | |
| SRP064894 | SDR16C5 | 195814 | RNAseq | -2.1892 | 0.0000 | |
| SRP133303 | SDR16C5 | 195814 | RNAseq | -1.1201 | 0.0069 | |
| SRP159526 | SDR16C5 | 195814 | RNAseq | -3.2731 | 0.0000 | |
| SRP193095 | SDR16C5 | 195814 | RNAseq | -1.9094 | 0.0000 | |
| SRP219564 | SDR16C5 | 195814 | RNAseq | -1.6406 | 0.2052 | |
| TCGA | SDR16C5 | 195814 | RNAseq | 0.1855 | 0.4495 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by SDR16C5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SDR16C5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SDR16C5 | 195814 | 14 | 1 | 15 | |
| GSE20123 | SDR16C5 | 195814 | 14 | 1 | 15 | |
| GSE43470 | SDR16C5 | 195814 | 13 | 3 | 27 | |
| GSE46452 | SDR16C5 | 195814 | 20 | 3 | 36 | |
| GSE47630 | SDR16C5 | 195814 | 23 | 1 | 16 | |
| GSE54993 | SDR16C5 | 195814 | 1 | 17 | 52 | |
| GSE54994 | SDR16C5 | 195814 | 29 | 0 | 24 | |
| GSE60625 | SDR16C5 | 195814 | 0 | 4 | 7 | |
| GSE74703 | SDR16C5 | 195814 | 12 | 2 | 22 | |
| GSE74704 | SDR16C5 | 195814 | 10 | 0 | 10 | |
| TCGA | SDR16C5 | 195814 | 44 | 8 | 44 |
Total number of gains: 180; Total number of losses: 40; Total Number of normals: 268.
Somatic mutations of SDR16C5:
Generating mutation plots.
Highly correlated genes for SDR16C5:
Showing top 20/900 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SDR16C5 | SH3PXD2A-AS1 | 0.744177 | 3 | 0 | 3 |
| SDR16C5 | PRSS2 | 0.731899 | 4 | 0 | 4 |
| SDR16C5 | FAXDC2 | 0.731374 | 3 | 0 | 3 |
| SDR16C5 | NEBL | 0.728648 | 6 | 0 | 6 |
| SDR16C5 | SPRR1A | 0.723682 | 5 | 0 | 5 |
| SDR16C5 | PLS1 | 0.72231 | 5 | 0 | 5 |
| SDR16C5 | ORMDL2 | 0.719155 | 4 | 0 | 4 |
| SDR16C5 | PRSS3 | 0.717606 | 6 | 0 | 5 |
| SDR16C5 | RHBDL2 | 0.71631 | 6 | 0 | 6 |
| SDR16C5 | SH3RF2 | 0.71126 | 4 | 0 | 4 |
| SDR16C5 | DSC2 | 0.708992 | 6 | 0 | 5 |
| SDR16C5 | C15orf48 | 0.708904 | 6 | 0 | 6 |
| SDR16C5 | STX7 | 0.707107 | 3 | 0 | 3 |
| SDR16C5 | CRCT1 | 0.702812 | 6 | 0 | 6 |
| SDR16C5 | ENDOU | 0.701358 | 6 | 0 | 5 |
| SDR16C5 | IL1RN | 0.70037 | 6 | 0 | 6 |
| SDR16C5 | TMEM50A | 0.697521 | 3 | 0 | 3 |
| SDR16C5 | CYP2C18 | 0.696747 | 5 | 0 | 4 |
| SDR16C5 | SERPINB13 | 0.695334 | 5 | 0 | 5 |
| SDR16C5 | DYNLT3 | 0.694217 | 5 | 0 | 5 |
For details and further investigation, click here
