| Full name: LY6/PLAUR domain containing 6B | Alias Symbol: CT116|LYPD7 | ||
| Type: protein-coding gene | Cytoband: 2q23.2 | ||
| Entrez ID: 130576 | HGNC ID: HGNC:27018 | Ensembl Gene: ENSG00000150556 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LYPD6B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LYPD6B | 130576 | 228360_at | 0.4593 | 0.6061 | |
| GSE26886 | LYPD6B | 130576 | 228360_at | 1.7914 | 0.0001 | |
| GSE45670 | LYPD6B | 130576 | 228360_at | 0.9710 | 0.0199 | |
| GSE53622 | LYPD6B | 130576 | 5802 | 1.8879 | 0.0000 | |
| GSE53624 | LYPD6B | 130576 | 5802 | 1.5049 | 0.0000 | |
| GSE63941 | LYPD6B | 130576 | 228360_at | 1.8738 | 0.1264 | |
| GSE77861 | LYPD6B | 130576 | 228360_at | 0.4694 | 0.0701 | |
| GSE97050 | LYPD6B | 130576 | A_23_P79302 | 0.6317 | 0.0828 | |
| SRP064894 | LYPD6B | 130576 | RNAseq | 1.2899 | 0.0019 | |
| SRP133303 | LYPD6B | 130576 | RNAseq | 2.6695 | 0.0000 | |
| SRP159526 | LYPD6B | 130576 | RNAseq | 2.8963 | 0.0000 | |
| SRP219564 | LYPD6B | 130576 | RNAseq | 1.9444 | 0.0348 | |
| TCGA | LYPD6B | 130576 | RNAseq | -0.4211 | 0.1086 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by LYPD6B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LYPD6B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LYPD6B | 130576 | 3 | 3 | 24 | |
| GSE20123 | LYPD6B | 130576 | 3 | 3 | 24 | |
| GSE43470 | LYPD6B | 130576 | 3 | 1 | 39 | |
| GSE46452 | LYPD6B | 130576 | 1 | 4 | 54 | |
| GSE47630 | LYPD6B | 130576 | 5 | 3 | 32 | |
| GSE54993 | LYPD6B | 130576 | 0 | 5 | 65 | |
| GSE54994 | LYPD6B | 130576 | 11 | 2 | 40 | |
| GSE60625 | LYPD6B | 130576 | 0 | 3 | 8 | |
| GSE74703 | LYPD6B | 130576 | 2 | 1 | 33 | |
| GSE74704 | LYPD6B | 130576 | 3 | 1 | 16 | |
| TCGA | LYPD6B | 130576 | 23 | 8 | 65 |
Total number of gains: 54; Total number of losses: 34; Total Number of normals: 400.
Somatic mutations of LYPD6B:
Generating mutation plots.
Highly correlated genes for LYPD6B:
Showing top 20/420 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LYPD6B | PHIP | 0.700812 | 3 | 0 | 3 |
| LYPD6B | ATXN2L | 0.695087 | 3 | 0 | 3 |
| LYPD6B | SULT1A1 | 0.684222 | 3 | 0 | 3 |
| LYPD6B | MSLN | 0.655965 | 4 | 0 | 3 |
| LYPD6B | FADD | 0.652093 | 4 | 0 | 3 |
| LYPD6B | PPFIA1 | 0.650525 | 4 | 0 | 3 |
| LYPD6B | SEPHS2 | 0.647756 | 4 | 0 | 3 |
| LYPD6B | AFG3L2 | 0.64178 | 4 | 0 | 3 |
| LYPD6B | TNFRSF18 | 0.640877 | 4 | 0 | 4 |
| LYPD6B | TUSC3 | 0.635593 | 4 | 0 | 3 |
| LYPD6B | HES6 | 0.632558 | 3 | 0 | 3 |
| LYPD6B | MDK | 0.632118 | 6 | 0 | 5 |
| LYPD6B | C15orf61 | 0.631521 | 4 | 0 | 3 |
| LYPD6B | SLFN5 | 0.630272 | 3 | 0 | 3 |
| LYPD6B | TTC30A | 0.629234 | 4 | 0 | 3 |
| LYPD6B | UGT8 | 0.629171 | 4 | 0 | 3 |
| LYPD6B | PKMYT1 | 0.627901 | 5 | 0 | 3 |
| LYPD6B | C19orf54 | 0.626416 | 4 | 0 | 3 |
| LYPD6B | ZNF367 | 0.624301 | 6 | 0 | 5 |
| LYPD6B | THOC6 | 0.622917 | 5 | 0 | 4 |
For details and further investigation, click here
