| Full name: supervillin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10p11.23 | ||
| Entrez ID: 6840 | HGNC ID: HGNC:11480 | Ensembl Gene: ENSG00000197321 | OMIM ID: 604126 |
| Drug and gene relationship at DGIdb | |||
Expression of SVIL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SVIL | 6840 | 202565_s_at | -0.8273 | 0.1202 | |
| GSE20347 | SVIL | 6840 | 202565_s_at | -0.4054 | 0.0463 | |
| GSE23400 | SVIL | 6840 | 202565_s_at | -0.2844 | 0.0305 | |
| GSE26886 | SVIL | 6840 | 202565_s_at | 0.4460 | 0.0291 | |
| GSE29001 | SVIL | 6840 | 202565_s_at | -0.4663 | 0.1590 | |
| GSE38129 | SVIL | 6840 | 202565_s_at | -0.5693 | 0.0188 | |
| GSE45670 | SVIL | 6840 | 202565_s_at | -0.5169 | 0.0074 | |
| GSE53622 | SVIL | 6840 | 114845 | -0.8633 | 0.0000 | |
| GSE53624 | SVIL | 6840 | 114845 | -0.6580 | 0.0000 | |
| GSE63941 | SVIL | 6840 | 202565_s_at | -0.5902 | 0.3997 | |
| GSE77861 | SVIL | 6840 | 202565_s_at | 0.1804 | 0.5834 | |
| GSE97050 | SVIL | 6840 | A_33_P3350413 | -0.0155 | 0.9547 | |
| SRP007169 | SVIL | 6840 | RNAseq | 0.8285 | 0.0197 | |
| SRP008496 | SVIL | 6840 | RNAseq | 0.8171 | 0.0001 | |
| SRP064894 | SVIL | 6840 | RNAseq | -0.7340 | 0.0031 | |
| SRP133303 | SVIL | 6840 | RNAseq | -0.3943 | 0.2091 | |
| SRP159526 | SVIL | 6840 | RNAseq | -0.7051 | 0.0624 | |
| SRP193095 | SVIL | 6840 | RNAseq | 0.0579 | 0.7590 | |
| SRP219564 | SVIL | 6840 | RNAseq | -1.0702 | 0.1461 | |
| TCGA | SVIL | 6840 | RNAseq | -0.0820 | 0.2734 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SVIL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SVIL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SVIL | 6840 | 5 | 7 | 18 | |
| GSE20123 | SVIL | 6840 | 5 | 6 | 19 | |
| GSE43470 | SVIL | 6840 | 3 | 4 | 36 | |
| GSE46452 | SVIL | 6840 | 1 | 14 | 44 | |
| GSE47630 | SVIL | 6840 | 5 | 15 | 20 | |
| GSE54993 | SVIL | 6840 | 9 | 0 | 61 | |
| GSE54994 | SVIL | 6840 | 3 | 10 | 40 | |
| GSE60625 | SVIL | 6840 | 0 | 0 | 11 | |
| GSE74703 | SVIL | 6840 | 2 | 2 | 32 | |
| GSE74704 | SVIL | 6840 | 0 | 5 | 15 | |
| TCGA | SVIL | 6840 | 19 | 23 | 54 |
Total number of gains: 52; Total number of losses: 86; Total Number of normals: 350.
Somatic mutations of SVIL:
Generating mutation plots.
Highly correlated genes for SVIL:
Showing top 20/128 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SVIL | NXPH3 | 0.70063 | 4 | 0 | 4 |
| SVIL | TUBA1A | 0.69776 | 4 | 0 | 4 |
| SVIL | PTCHD1 | 0.694987 | 4 | 0 | 4 |
| SVIL | C6 | 0.680159 | 3 | 0 | 3 |
| SVIL | RYR2 | 0.676265 | 6 | 0 | 5 |
| SVIL | COX20 | 0.675784 | 3 | 0 | 3 |
| SVIL | ARIH2OS | 0.6756 | 3 | 0 | 3 |
| SVIL | DACT3 | 0.674619 | 4 | 0 | 3 |
| SVIL | CSRP1 | 0.665008 | 8 | 0 | 7 |
| SVIL | LPP | 0.659102 | 9 | 0 | 8 |
| SVIL | ADAMTS9-AS2 | 0.65475 | 4 | 0 | 3 |
| SVIL | KBTBD12 | 0.653356 | 3 | 0 | 3 |
| SVIL | GSTM5 | 0.647525 | 5 | 0 | 4 |
| SVIL | RAI2 | 0.63928 | 7 | 0 | 6 |
| SVIL | PLCXD3 | 0.629913 | 3 | 0 | 3 |
| SVIL | PRKCB | 0.625618 | 4 | 0 | 3 |
| SVIL | FBXL7 | 0.622442 | 8 | 0 | 6 |
| SVIL | KANK3 | 0.61993 | 3 | 0 | 3 |
| SVIL | PLP1 | 0.6197 | 6 | 0 | 4 |
| SVIL | GPM6A | 0.619335 | 5 | 0 | 4 |
For details and further investigation, click here
