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Multi-Omics Database of ESCC

 

RBP1

 

Full name: retinol binding protein 1 Alias Symbol: CRABP-I|CRBP1|CRBP|RBPC|CRBPI
Type: protein-coding gene Cytoband: 3q23
Entrez ID: 5947 HGNC ID: HGNC:9919 Ensembl Gene: ENSG00000114115 OMIM ID: 180260
Drug and gene relationship at DGIdb

 

Expression of RBP1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RBP1 5947 203423_at 1.6925 0.3128
GSE20347 RBP1 5947 203423_at 1.9175 0.0005
GSE23400 RBP1 5947 203423_at 1.2068 0.0000
GSE26886 RBP1 5947 203423_at 2.4334 0.0001
GSE29001 RBP1 5947 203423_at 1.3381 0.0102
GSE38129 RBP1 5947 203423_at 1.6792 0.0000
GSE45670 RBP1 5947 203423_at 2.0530 0.0005
GSE53622 RBP1 5947 6946 1.9357 0.0000
GSE53624 RBP1 5947 6946 1.8463 0.0000
GSE63941 RBP1 5947 203423_at 0.0061 0.9982
GSE77861 RBP1 5947 203423_at 2.6426 0.0085
GSE97050 RBP1 5947 A_23_P257649 1.7168 0.1189
SRP007169 RBP1 5947 RNAseq 2.2982 0.0020
SRP008496 RBP1 5947 RNAseq 2.0492 0.0007
SRP064894 RBP1 5947 RNAseq 1.9368 0.0000
SRP133303 RBP1 5947 RNAseq 2.3921 0.0000
SRP159526 RBP1 5947 RNAseq 1.0652 0.0080
SRP193095 RBP1 5947 RNAseq 2.2968 0.0000
SRP219564 RBP1 5947 RNAseq 1.1790 0.0424
TCGA RBP1 5947 RNAseq 0.7799 0.0000

Upregulated datasets: 16; Downregulated datasets: 0.  

 

Survival by RBP1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RBP1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RBP1 5947 18 0 12
GSE20123 RBP1 5947 18 0 12
GSE43470 RBP1 5947 22 0 21
GSE46452 RBP1 5947 15 4 40
GSE47630 RBP1 5947 19 3 18
GSE54993 RBP1 5947 2 8 60
GSE54994 RBP1 5947 32 2 19
GSE60625 RBP1 5947 0 6 5
GSE74703 RBP1 5947 19 0 17
GSE74704 RBP1 5947 12 0 8
TCGA RBP1 5947 61 4 31

Total number of gains: 218; Total number of losses: 27; Total Number of normals: 243.  

 

Somatic mutations of RBP1:

 

Generating mutation plots.

 

Highly correlated genes for RBP1:

 

Showing top 20/1635 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RBP1SPRR2G0.776682303
RBP1TENM20.762909606
RBP1XPR10.762077707
RBP1CD2760.761077404
RBP1FMNL20.758187707
RBP1BLACAT10.757035404
RBP1TTYH30.750801707
RBP1WDR540.737374807
RBP1DCBLD10.735348807
RBP1INHBA0.7292411009
RBP1DOCK110.722569303
RBP1LOXL20.72220611011
RBP1HSD17B10.715936404
RBP1SH3PXD2B0.713973707
RBP1FSCN10.71363911010
RBP1MTBP0.712048404
RBP1RTKN0.711806707
RBP1GLS0.711697606
RBP1CDCA20.711372505
RBP1CPT1A0.711356404

For details and further investigation, click here