| Full name: teneurin transmembrane protein 3 | Alias Symbol: Ten-M3|KIAA1455 | ||
| Type: protein-coding gene | Cytoband: 4q34.3-q35.1 | ||
| Entrez ID: 55714 | HGNC ID: HGNC:29944 | Ensembl Gene: ENSG00000218336 | OMIM ID: 610083 |
| Drug and gene relationship at DGIdb | |||
Expression of TENM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TENM3 | 55714 | 219523_s_at | 0.3770 | 0.6433 | |
| GSE20347 | TENM3 | 55714 | 219523_s_at | 0.3703 | 0.1641 | |
| GSE23400 | TENM3 | 55714 | 219523_s_at | 0.1103 | 0.0048 | |
| GSE26886 | TENM3 | 55714 | 227050_at | 0.5134 | 0.0008 | |
| GSE29001 | TENM3 | 55714 | 219523_s_at | 0.6152 | 0.1118 | |
| GSE38129 | TENM3 | 55714 | 219523_s_at | 0.2955 | 0.1595 | |
| GSE45670 | TENM3 | 55714 | 219523_s_at | 0.0548 | 0.8655 | |
| GSE53622 | TENM3 | 55714 | 41737 | 1.4513 | 0.0000 | |
| GSE53624 | TENM3 | 55714 | 41737 | 1.9404 | 0.0000 | |
| GSE63941 | TENM3 | 55714 | 219523_s_at | -0.6749 | 0.3580 | |
| GSE77861 | TENM3 | 55714 | 219523_s_at | -0.0596 | 0.7777 | |
| SRP007169 | TENM3 | 55714 | RNAseq | 4.1523 | 0.0000 | |
| SRP008496 | TENM3 | 55714 | RNAseq | 5.1193 | 0.0000 | |
| SRP064894 | TENM3 | 55714 | RNAseq | 2.2804 | 0.0000 | |
| SRP133303 | TENM3 | 55714 | RNAseq | 2.4887 | 0.0000 | |
| SRP159526 | TENM3 | 55714 | RNAseq | 1.1974 | 0.0151 | |
| SRP219564 | TENM3 | 55714 | RNAseq | 0.4012 | 0.6091 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by TENM3 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TENM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TENM3 | 55714 | 2 | 11 | 17 | |
| GSE20123 | TENM3 | 55714 | 2 | 11 | 17 | |
| GSE43470 | TENM3 | 55714 | 0 | 12 | 31 | |
| GSE46452 | TENM3 | 55714 | 1 | 36 | 22 | |
| GSE47630 | TENM3 | 55714 | 0 | 22 | 18 | |
| GSE54993 | TENM3 | 55714 | 10 | 0 | 60 | |
| GSE54994 | TENM3 | 55714 | 2 | 12 | 39 | |
| GSE60625 | TENM3 | 55714 | 0 | 0 | 11 | |
| GSE74703 | TENM3 | 55714 | 0 | 10 | 26 | |
| GSE74704 | TENM3 | 55714 | 1 | 5 | 14 | |
| TCGA | TENM3 | 55714 | 10 | 36 | 50 |
Total number of gains: 28; Total number of losses: 155; Total Number of normals: 305.
Somatic mutations of TENM3:
Generating mutation plots.
Highly correlated genes for TENM3:
Showing top 20/292 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TENM3 | B3GNT9 | 0.686308 | 4 | 0 | 4 |
| TENM3 | ASB2 | 0.670556 | 3 | 0 | 3 |
| TENM3 | ITGA11 | 0.670327 | 3 | 0 | 3 |
| TENM3 | DNM1 | 0.661818 | 3 | 0 | 3 |
| TENM3 | BEND6 | 0.65168 | 5 | 0 | 5 |
| TENM3 | DLK1 | 0.632536 | 3 | 0 | 3 |
| TENM3 | CITED1 | 0.624176 | 3 | 0 | 3 |
| TENM3 | IL27RA | 0.624057 | 3 | 0 | 3 |
| TENM3 | RTTN | 0.621081 | 3 | 0 | 3 |
| TENM3 | COL5A3 | 0.61388 | 9 | 0 | 7 |
| TENM3 | COL24A1 | 0.612147 | 4 | 0 | 3 |
| TENM3 | SAGE1 | 0.61214 | 4 | 0 | 3 |
| TENM3 | WDR86 | 0.607267 | 4 | 0 | 3 |
| TENM3 | KANK4 | 0.60614 | 5 | 0 | 4 |
| TENM3 | NKX3-2 | 0.602835 | 5 | 0 | 4 |
| TENM3 | LGALS1 | 0.602188 | 9 | 0 | 9 |
| TENM3 | SCARB1 | 0.601733 | 3 | 0 | 3 |
| TENM3 | GPX8 | 0.601547 | 6 | 0 | 5 |
| TENM3 | COL12A1 | 0.601502 | 6 | 0 | 4 |
| TENM3 | IKBIP | 0.599604 | 4 | 0 | 3 |
For details and further investigation, click here
