| Full name: transmembrane p24 trafficking protein 6 | Alias Symbol: MGC23911|p24gamma5|p24g5 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 146456 | HGNC ID: HGNC:28331 | Ensembl Gene: ENSG00000157315 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMED6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMED6 | 146456 | 236430_at | 0.2234 | 0.2419 | |
| GSE26886 | TMED6 | 146456 | 236430_at | 0.0997 | 0.3949 | |
| GSE45670 | TMED6 | 146456 | 236430_at | 0.1099 | 0.4240 | |
| GSE53622 | TMED6 | 146456 | 12323 | -0.4335 | 0.0063 | |
| GSE53624 | TMED6 | 146456 | 12323 | -0.2436 | 0.0579 | |
| GSE63941 | TMED6 | 146456 | 236430_at | 0.0222 | 0.9076 | |
| GSE77861 | TMED6 | 146456 | 236430_at | 0.0542 | 0.5129 | |
| GSE97050 | TMED6 | 146456 | A_23_P26570 | 0.1674 | 0.5084 | |
| SRP133303 | TMED6 | 146456 | RNAseq | -0.1599 | 0.5525 | |
| SRP159526 | TMED6 | 146456 | RNAseq | -0.5061 | 0.4285 | |
| TCGA | TMED6 | 146456 | RNAseq | -3.2277 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMED6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMED6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMED6 | 146456 | 8 | 1 | 21 | |
| GSE20123 | TMED6 | 146456 | 8 | 1 | 21 | |
| GSE43470 | TMED6 | 146456 | 2 | 7 | 34 | |
| GSE46452 | TMED6 | 146456 | 38 | 1 | 20 | |
| GSE47630 | TMED6 | 146456 | 11 | 8 | 21 | |
| GSE54993 | TMED6 | 146456 | 2 | 4 | 64 | |
| GSE54994 | TMED6 | 146456 | 8 | 10 | 35 | |
| GSE60625 | TMED6 | 146456 | 4 | 0 | 7 | |
| GSE74703 | TMED6 | 146456 | 2 | 4 | 30 | |
| GSE74704 | TMED6 | 146456 | 4 | 0 | 16 | |
| TCGA | TMED6 | 146456 | 29 | 12 | 55 |
Total number of gains: 116; Total number of losses: 48; Total Number of normals: 324.
Somatic mutations of TMED6:
Generating mutation plots.
Highly correlated genes for TMED6:
Showing top 20/45 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMED6 | HNRNPA2B1 | 0.709776 | 3 | 0 | 3 |
| TMED6 | FANCB | 0.694681 | 3 | 0 | 3 |
| TMED6 | GC | 0.6747 | 3 | 0 | 3 |
| TMED6 | HOXA10 | 0.667419 | 3 | 0 | 3 |
| TMED6 | EXOSC9 | 0.654576 | 3 | 0 | 3 |
| TMED6 | HSPE1 | 0.652911 | 4 | 0 | 4 |
| TMED6 | LSM1 | 0.65264 | 4 | 0 | 4 |
| TMED6 | TMED1 | 0.651631 | 3 | 0 | 3 |
| TMED6 | BRF2 | 0.647645 | 3 | 0 | 3 |
| TMED6 | NUDC | 0.641764 | 3 | 0 | 3 |
| TMED6 | TRIP13 | 0.639765 | 3 | 0 | 3 |
| TMED6 | EIF3B | 0.63665 | 3 | 0 | 3 |
| TMED6 | DDX31 | 0.630571 | 3 | 0 | 3 |
| TMED6 | TNIP2 | 0.627916 | 3 | 0 | 3 |
| TMED6 | MCM4 | 0.623837 | 3 | 0 | 3 |
| TMED6 | TYK2 | 0.611127 | 3 | 0 | 3 |
| TMED6 | CLPTM1L | 0.607023 | 3 | 0 | 3 |
| TMED6 | LYPD1 | 0.605647 | 3 | 0 | 3 |
| TMED6 | BUB3 | 0.601303 | 3 | 0 | 3 |
| TMED6 | TRMT112 | 0.596924 | 3 | 0 | 3 |
For details and further investigation, click here
