TMEM106C

 

Full name: transmembrane protein 106C Alias Symbol: MGC5576
Type: protein-coding gene Cytoband: 12q13.11
Entrez ID: 79022 HGNC ID: HGNC:28775 Ensembl Gene: ENSG00000134291 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TMEM106C:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM106C 79022 201764_at 0.6469 0.1694
GSE20347 TMEM106C 79022 201764_at 0.7603 0.0039
GSE23400 TMEM106C 79022 201764_at 0.2810 0.0000
GSE26886 TMEM106C 79022 201764_at 0.2125 0.1103
GSE29001 TMEM106C 79022 201764_at 0.7398 0.0024
GSE38129 TMEM106C 79022 201764_at 0.6891 0.0002
GSE45670 TMEM106C 79022 201764_at 0.4679 0.0046
GSE53622 TMEM106C 79022 152784 0.4097 0.0000
GSE53624 TMEM106C 79022 152784 0.8025 0.0000
GSE63941 TMEM106C 79022 201764_at 1.3375 0.0016
GSE77861 TMEM106C 79022 201764_at 0.2969 0.1764
GSE97050 TMEM106C 79022 A_23_P48175 0.0225 0.9668
SRP007169 TMEM106C 79022 RNAseq 1.2211 0.0512
SRP008496 TMEM106C 79022 RNAseq 0.9478 0.0077
SRP064894 TMEM106C 79022 RNAseq 0.6774 0.0087
SRP133303 TMEM106C 79022 RNAseq 1.0032 0.0000
SRP159526 TMEM106C 79022 RNAseq 0.6236 0.0029
SRP193095 TMEM106C 79022 RNAseq 0.4144 0.0467
SRP219564 TMEM106C 79022 RNAseq 0.5222 0.1282
TCGA TMEM106C 79022 RNAseq 0.0649 0.2739

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by TMEM106C expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TMEM106C:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM106C 79022 7 1 22
GSE20123 TMEM106C 79022 7 1 22
GSE43470 TMEM106C 79022 3 1 39
GSE46452 TMEM106C 79022 8 1 50
GSE47630 TMEM106C 79022 11 2 27
GSE54993 TMEM106C 79022 0 5 65
GSE54994 TMEM106C 79022 6 1 46
GSE60625 TMEM106C 79022 0 0 11
GSE74703 TMEM106C 79022 3 1 32
GSE74704 TMEM106C 79022 4 1 15
TCGA TMEM106C 79022 16 12 68

Total number of gains: 65; Total number of losses: 26; Total Number of normals: 397.  

 

Somatic mutations of TMEM106C:

 

Generating mutation plots.

 

Highly correlated genes for TMEM106C:

 

Showing top 20/878 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM106CMRPL380.736391303
TMEM106CFAM102B0.725691303
TMEM106CPPP5C0.719668303
TMEM106CZNF6410.714479303
TMEM106CADO0.712151606
TMEM106CTBC1D80.705269303
TMEM106CPSIP10.692348404
TMEM106CCPNE80.686743303
TMEM106CSWT10.684069303
TMEM106CCERS50.674484504
TMEM106CSFT2D30.673739403
TMEM106CGIGYF10.663986403
TMEM106CRFC40.65854712010
TMEM106CSYT170.655112303
TMEM106CTUBA1B0.654372707
TMEM106CORAI10.653642403
TMEM106CTMEM2160.652186303
TMEM106CLMBR10.65186303
TMEM106CNABP20.643271009
TMEM106CMSH60.6418731309

For details and further investigation, click here