| Full name: transmembrane protein 130 | Alias Symbol: DKFZp761L1417|FLJ42643 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 222865 | HGNC ID: HGNC:25429 | Ensembl Gene: ENSG00000166448 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM130:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM130 | 222865 | 238426_at | -0.0025 | 0.9941 | |
| GSE26886 | TMEM130 | 222865 | 238426_at | 0.1230 | 0.2084 | |
| GSE45670 | TMEM130 | 222865 | 238426_at | -0.1964 | 0.0288 | |
| GSE53622 | TMEM130 | 222865 | 30353 | 0.5530 | 0.0146 | |
| GSE53624 | TMEM130 | 222865 | 30353 | 0.7732 | 0.0001 | |
| GSE63941 | TMEM130 | 222865 | 238426_at | -2.0825 | 0.0000 | |
| GSE77861 | TMEM130 | 222865 | 238426_at | -0.1127 | 0.4328 | |
| SRP064894 | TMEM130 | 222865 | RNAseq | 0.4148 | 0.1766 | |
| SRP133303 | TMEM130 | 222865 | RNAseq | 0.0644 | 0.6219 | |
| SRP159526 | TMEM130 | 222865 | RNAseq | 1.3591 | 0.0682 | |
| SRP193095 | TMEM130 | 222865 | RNAseq | 0.1199 | 0.4544 | |
| SRP219564 | TMEM130 | 222865 | RNAseq | 0.5623 | 0.3600 | |
| TCGA | TMEM130 | 222865 | RNAseq | -0.8609 | 0.0393 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMEM130 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM130:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM130 | 222865 | 13 | 0 | 17 | |
| GSE20123 | TMEM130 | 222865 | 13 | 0 | 17 | |
| GSE43470 | TMEM130 | 222865 | 6 | 1 | 36 | |
| GSE46452 | TMEM130 | 222865 | 12 | 0 | 47 | |
| GSE47630 | TMEM130 | 222865 | 8 | 3 | 29 | |
| GSE54993 | TMEM130 | 222865 | 1 | 9 | 60 | |
| GSE54994 | TMEM130 | 222865 | 16 | 3 | 34 | |
| GSE60625 | TMEM130 | 222865 | 0 | 0 | 11 | |
| GSE74703 | TMEM130 | 222865 | 6 | 1 | 29 | |
| GSE74704 | TMEM130 | 222865 | 9 | 0 | 11 | |
| TCGA | TMEM130 | 222865 | 54 | 4 | 38 |
Total number of gains: 138; Total number of losses: 21; Total Number of normals: 329.
Somatic mutations of TMEM130:
Generating mutation plots.
Highly correlated genes for TMEM130:
Showing top 20/116 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM130 | PKD2 | 0.716883 | 3 | 0 | 3 |
| TMEM130 | TNFSF4 | 0.706753 | 3 | 0 | 3 |
| TMEM130 | GALNT15 | 0.695066 | 3 | 0 | 3 |
| TMEM130 | PCDH18 | 0.694078 | 3 | 0 | 3 |
| TMEM130 | VSTM4 | 0.67944 | 4 | 0 | 4 |
| TMEM130 | FKBP7 | 0.677881 | 3 | 0 | 3 |
| TMEM130 | GRIN3A | 0.672589 | 3 | 0 | 3 |
| TMEM130 | SCG5 | 0.653256 | 4 | 0 | 3 |
| TMEM130 | RARRES2 | 0.646998 | 4 | 0 | 3 |
| TMEM130 | SCN4B | 0.646044 | 3 | 0 | 3 |
| TMEM130 | GPC6 | 0.645385 | 4 | 0 | 3 |
| TMEM130 | DDR2 | 0.643575 | 4 | 0 | 3 |
| TMEM130 | NAP1L3 | 0.639076 | 4 | 0 | 3 |
| TMEM130 | FLNC | 0.638236 | 3 | 0 | 3 |
| TMEM130 | CPQ | 0.632378 | 4 | 0 | 3 |
| TMEM130 | DOK1 | 0.628599 | 3 | 0 | 3 |
| TMEM130 | SVEP1 | 0.627374 | 4 | 0 | 3 |
| TMEM130 | DAB2 | 0.626129 | 4 | 0 | 3 |
| TMEM130 | HSD11B1 | 0.625112 | 4 | 0 | 3 |
| TMEM130 | SPOCK1 | 0.623555 | 3 | 0 | 3 |
For details and further investigation, click here
