| Full name: BMP2 inducible kinase | Alias Symbol: DKFZp434K0614|BIKe | ||
| Type: protein-coding gene | Cytoband: 4q21.21 | ||
| Entrez ID: 55589 | HGNC ID: HGNC:18041 | Ensembl Gene: ENSG00000138756 | OMIM ID: 617648 |
| Drug and gene relationship at DGIdb | |||
Expression of BMP2K:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BMP2K | 55589 | 226853_at | -0.0832 | 0.8706 | |
| GSE20347 | BMP2K | 55589 | 219546_at | -0.8357 | 0.0000 | |
| GSE23400 | BMP2K | 55589 | 59644_at | -0.0982 | 0.0352 | |
| GSE26886 | BMP2K | 55589 | 219546_at | -0.3963 | 0.1594 | |
| GSE29001 | BMP2K | 55589 | 59644_at | -0.7271 | 0.0381 | |
| GSE38129 | BMP2K | 55589 | 219546_at | -0.4442 | 0.0079 | |
| GSE45670 | BMP2K | 55589 | 226853_at | -0.1561 | 0.5090 | |
| GSE53622 | BMP2K | 55589 | 70595 | -0.2232 | 0.0049 | |
| GSE53624 | BMP2K | 55589 | 125125 | -0.5976 | 0.0000 | |
| GSE63941 | BMP2K | 55589 | 219546_at | -1.5758 | 0.0040 | |
| GSE77861 | BMP2K | 55589 | 37170_at | -0.0450 | 0.8530 | |
| GSE97050 | BMP2K | 55589 | A_24_P86240 | 0.0931 | 0.7312 | |
| SRP007169 | BMP2K | 55589 | RNAseq | -0.7245 | 0.0314 | |
| SRP008496 | BMP2K | 55589 | RNAseq | -0.4259 | 0.1131 | |
| SRP064894 | BMP2K | 55589 | RNAseq | -0.6401 | 0.0236 | |
| SRP133303 | BMP2K | 55589 | RNAseq | -0.2368 | 0.1912 | |
| SRP159526 | BMP2K | 55589 | RNAseq | -0.9857 | 0.0003 | |
| SRP193095 | BMP2K | 55589 | RNAseq | -0.3139 | 0.0157 | |
| SRP219564 | BMP2K | 55589 | RNAseq | -0.4900 | 0.3331 | |
| TCGA | BMP2K | 55589 | RNAseq | -0.0185 | 0.8377 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by BMP2K expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BMP2K:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BMP2K | 55589 | 1 | 10 | 19 | |
| GSE20123 | BMP2K | 55589 | 1 | 10 | 19 | |
| GSE43470 | BMP2K | 55589 | 0 | 13 | 30 | |
| GSE46452 | BMP2K | 55589 | 1 | 36 | 22 | |
| GSE47630 | BMP2K | 55589 | 1 | 19 | 20 | |
| GSE54993 | BMP2K | 55589 | 8 | 0 | 62 | |
| GSE54994 | BMP2K | 55589 | 0 | 9 | 44 | |
| GSE60625 | BMP2K | 55589 | 0 | 0 | 11 | |
| GSE74703 | BMP2K | 55589 | 0 | 11 | 25 | |
| GSE74704 | BMP2K | 55589 | 1 | 6 | 13 | |
| TCGA | BMP2K | 55589 | 12 | 33 | 51 |
Total number of gains: 25; Total number of losses: 147; Total Number of normals: 316.
Somatic mutations of BMP2K:
Generating mutation plots.
Highly correlated genes for BMP2K:
Showing top 20/485 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BMP2K | MAP4K4 | 0.733493 | 3 | 0 | 3 |
| BMP2K | TMUB2 | 0.723415 | 3 | 0 | 3 |
| BMP2K | NTAN1 | 0.715001 | 4 | 0 | 4 |
| BMP2K | FBXO42 | 0.70537 | 4 | 0 | 4 |
| BMP2K | TMEM120A | 0.70456 | 3 | 0 | 3 |
| BMP2K | UBQLN1 | 0.699241 | 3 | 0 | 3 |
| BMP2K | NFIC | 0.692336 | 4 | 0 | 3 |
| BMP2K | FZD4 | 0.687972 | 3 | 0 | 3 |
| BMP2K | LYSMD3 | 0.683841 | 3 | 0 | 3 |
| BMP2K | LCA5 | 0.672903 | 3 | 0 | 3 |
| BMP2K | SPRY1 | 0.671578 | 3 | 0 | 3 |
| BMP2K | RAP1GDS1 | 0.65265 | 10 | 0 | 9 |
| BMP2K | NFXL1 | 0.651144 | 3 | 0 | 3 |
| BMP2K | RAPGEF2 | 0.648444 | 4 | 0 | 3 |
| BMP2K | NEK1 | 0.647853 | 3 | 0 | 3 |
| BMP2K | MAP4K5 | 0.646632 | 4 | 0 | 3 |
| BMP2K | ZNF555 | 0.646407 | 4 | 0 | 3 |
| BMP2K | RUNDC3B | 0.637926 | 3 | 0 | 3 |
| BMP2K | RNF145 | 0.637236 | 4 | 0 | 3 |
| BMP2K | ELOVL1 | 0.636678 | 3 | 0 | 3 |
For details and further investigation, click here
