| Full name: tankyrase 1 binding protein 1 | Alias Symbol: TAB182|KIAA1741|FLJ45975 | ||
| Type: protein-coding gene | Cytoband: 11q12.1 | ||
| Entrez ID: 85456 | HGNC ID: HGNC:19081 | Ensembl Gene: ENSG00000149115 | OMIM ID: 607104 |
| Drug and gene relationship at DGIdb | |||
Expression of TNKS1BP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNKS1BP1 | 85456 | 224792_at | 0.2121 | 0.6929 | |
| GSE26886 | TNKS1BP1 | 85456 | 224792_at | 0.2350 | 0.3442 | |
| GSE45670 | TNKS1BP1 | 85456 | 224792_at | 0.1522 | 0.1889 | |
| GSE53622 | TNKS1BP1 | 85456 | 2954 | -0.1549 | 0.1302 | |
| GSE53624 | TNKS1BP1 | 85456 | 2954 | -0.1577 | 0.0165 | |
| GSE63941 | TNKS1BP1 | 85456 | 224792_at | 0.4784 | 0.2424 | |
| GSE77861 | TNKS1BP1 | 85456 | 224792_at | 0.3297 | 0.1838 | |
| GSE97050 | TNKS1BP1 | 85456 | A_23_P418597 | 0.1565 | 0.6021 | |
| SRP007169 | TNKS1BP1 | 85456 | RNAseq | 0.2999 | 0.4721 | |
| SRP008496 | TNKS1BP1 | 85456 | RNAseq | 0.0792 | 0.7802 | |
| SRP064894 | TNKS1BP1 | 85456 | RNAseq | -0.4245 | 0.0050 | |
| SRP133303 | TNKS1BP1 | 85456 | RNAseq | -0.0567 | 0.7848 | |
| SRP159526 | TNKS1BP1 | 85456 | RNAseq | -0.5497 | 0.0197 | |
| SRP193095 | TNKS1BP1 | 85456 | RNAseq | -0.0024 | 0.9892 | |
| SRP219564 | TNKS1BP1 | 85456 | RNAseq | -0.1147 | 0.6447 | |
| TCGA | TNKS1BP1 | 85456 | RNAseq | -0.0506 | 0.3103 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TNKS1BP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNKS1BP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNKS1BP1 | 85456 | 2 | 3 | 25 | |
| GSE20123 | TNKS1BP1 | 85456 | 2 | 3 | 25 | |
| GSE43470 | TNKS1BP1 | 85456 | 1 | 5 | 37 | |
| GSE46452 | TNKS1BP1 | 85456 | 9 | 4 | 46 | |
| GSE47630 | TNKS1BP1 | 85456 | 3 | 9 | 28 | |
| GSE54993 | TNKS1BP1 | 85456 | 3 | 0 | 67 | |
| GSE54994 | TNKS1BP1 | 85456 | 5 | 6 | 42 | |
| GSE60625 | TNKS1BP1 | 85456 | 0 | 3 | 8 | |
| GSE74703 | TNKS1BP1 | 85456 | 1 | 3 | 32 | |
| GSE74704 | TNKS1BP1 | 85456 | 2 | 3 | 15 | |
| TCGA | TNKS1BP1 | 85456 | 14 | 10 | 72 |
Total number of gains: 42; Total number of losses: 49; Total Number of normals: 397.
Somatic mutations of TNKS1BP1:
Generating mutation plots.
Highly correlated genes for TNKS1BP1:
Showing top 20/297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNKS1BP1 | SPHK1 | 0.707797 | 3 | 0 | 3 |
| TNKS1BP1 | OTUB1 | 0.702441 | 3 | 0 | 3 |
| TNKS1BP1 | GP1BA | 0.696798 | 3 | 0 | 3 |
| TNKS1BP1 | ARHGEF19 | 0.685856 | 3 | 0 | 3 |
| TNKS1BP1 | HOXD8 | 0.682853 | 3 | 0 | 3 |
| TNKS1BP1 | CTDNEP1 | 0.679214 | 4 | 0 | 4 |
| TNKS1BP1 | VAC14 | 0.664634 | 3 | 0 | 3 |
| TNKS1BP1 | BAIAP2L1 | 0.657781 | 4 | 0 | 3 |
| TNKS1BP1 | DOLK | 0.656816 | 3 | 0 | 3 |
| TNKS1BP1 | PSMC4 | 0.65052 | 4 | 0 | 4 |
| TNKS1BP1 | FAM83G | 0.647867 | 6 | 0 | 6 |
| TNKS1BP1 | KDM5C | 0.645095 | 4 | 0 | 4 |
| TNKS1BP1 | AP2S1 | 0.644733 | 5 | 0 | 4 |
| TNKS1BP1 | CFL1 | 0.64366 | 7 | 0 | 5 |
| TNKS1BP1 | KDELR1 | 0.643563 | 3 | 0 | 3 |
| TNKS1BP1 | BIN3 | 0.643384 | 3 | 0 | 3 |
| TNKS1BP1 | SERINC2 | 0.643194 | 6 | 0 | 6 |
| TNKS1BP1 | SLC25A39 | 0.642289 | 4 | 0 | 3 |
| TNKS1BP1 | MARK2 | 0.637784 | 9 | 0 | 9 |
| TNKS1BP1 | SLC50A1 | 0.63633 | 4 | 0 | 3 |
For details and further investigation, click here
