| Full name: chromosome 11 open reading frame 45 | Alias Symbol: MGC35558|FLJ43646 | ||
| Type: protein-coding gene | Cytoband: 11q24.3 | ||
| Entrez ID: 219833 | HGNC ID: HGNC:28584 | Ensembl Gene: ENSG00000174370 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C11orf45:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C11orf45 | 219833 | 1553787_at | -0.1103 | 0.8717 | |
| GSE26886 | C11orf45 | 219833 | 1553787_at | -0.5158 | 0.0623 | |
| GSE45670 | C11orf45 | 219833 | 1553787_at | -0.0231 | 0.9365 | |
| GSE53622 | C11orf45 | 219833 | 79140 | -0.0720 | 0.7255 | |
| GSE53624 | C11orf45 | 219833 | 79140 | -0.3280 | 0.0542 | |
| GSE63941 | C11orf45 | 219833 | 1553787_at | 0.5490 | 0.3700 | |
| GSE77861 | C11orf45 | 219833 | 1553787_at | -0.6112 | 0.0091 | |
| GSE97050 | C11orf45 | 219833 | A_23_P420293 | -0.0849 | 0.8251 | |
| SRP007169 | C11orf45 | 219833 | RNAseq | 0.2436 | 0.7257 | |
| SRP064894 | C11orf45 | 219833 | RNAseq | 0.5532 | 0.0954 | |
| SRP133303 | C11orf45 | 219833 | RNAseq | -0.9131 | 0.0023 | |
| SRP159526 | C11orf45 | 219833 | RNAseq | -0.8529 | 0.0386 | |
| SRP193095 | C11orf45 | 219833 | RNAseq | -0.7864 | 0.0027 | |
| SRP219564 | C11orf45 | 219833 | RNAseq | -0.5081 | 0.2789 | |
| TCGA | C11orf45 | 219833 | RNAseq | 0.6300 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C11orf45 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C11orf45:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C11orf45 | 219833 | 0 | 13 | 17 | |
| GSE20123 | C11orf45 | 219833 | 0 | 13 | 17 | |
| GSE43470 | C11orf45 | 219833 | 2 | 7 | 34 | |
| GSE46452 | C11orf45 | 219833 | 3 | 26 | 30 | |
| GSE47630 | C11orf45 | 219833 | 2 | 19 | 19 | |
| GSE54993 | C11orf45 | 219833 | 10 | 0 | 60 | |
| GSE54994 | C11orf45 | 219833 | 5 | 19 | 29 | |
| GSE60625 | C11orf45 | 219833 | 0 | 3 | 8 | |
| GSE74703 | C11orf45 | 219833 | 1 | 5 | 30 | |
| GSE74704 | C11orf45 | 219833 | 0 | 9 | 11 | |
| TCGA | C11orf45 | 219833 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of C11orf45:
Generating mutation plots.
Highly correlated genes for C11orf45:
Showing top 20/249 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C11orf45 | AGPAT3 | 0.760642 | 3 | 0 | 3 |
| C11orf45 | TMEM9B | 0.739486 | 3 | 0 | 3 |
| C11orf45 | MKRN2 | 0.698409 | 3 | 0 | 3 |
| C11orf45 | CNPPD1 | 0.693305 | 3 | 0 | 3 |
| C11orf45 | DLG2 | 0.692066 | 3 | 0 | 3 |
| C11orf45 | EPB41 | 0.689152 | 3 | 0 | 3 |
| C11orf45 | TRAFD1 | 0.684273 | 4 | 0 | 3 |
| C11orf45 | SCP2 | 0.68417 | 4 | 0 | 3 |
| C11orf45 | SEC24C | 0.678738 | 3 | 0 | 3 |
| C11orf45 | ACOX3 | 0.677976 | 3 | 0 | 3 |
| C11orf45 | AMOTL2 | 0.674908 | 3 | 0 | 3 |
| C11orf45 | ELL3 | 0.670633 | 3 | 0 | 3 |
| C11orf45 | MSRA | 0.66904 | 3 | 0 | 3 |
| C11orf45 | DNAJC28 | 0.665524 | 3 | 0 | 3 |
| C11orf45 | TMEM220 | 0.662338 | 3 | 0 | 3 |
| C11orf45 | MBNL3 | 0.661446 | 3 | 0 | 3 |
| C11orf45 | RETSAT | 0.660749 | 5 | 0 | 4 |
| C11orf45 | RASSF5 | 0.660002 | 3 | 0 | 3 |
| C11orf45 | VPS26A | 0.658572 | 3 | 0 | 3 |
| C11orf45 | SUFU | 0.657201 | 4 | 0 | 4 |
For details and further investigation, click here
