| Full name: translocation associated membrane protein 1 | Alias Symbol: TRAM|TRAMP | ||
| Type: protein-coding gene | Cytoband: 8q13.3 | ||
| Entrez ID: 23471 | HGNC ID: HGNC:20568 | Ensembl Gene: ENSG00000067167 | OMIM ID: 605190 |
| Drug and gene relationship at DGIdb | |||
Expression of TRAM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRAM1 | 23471 | 201398_s_at | 0.3700 | 0.1603 | |
| GSE20347 | TRAM1 | 23471 | 201398_s_at | 0.1867 | 0.2614 | |
| GSE23400 | TRAM1 | 23471 | 201398_s_at | 0.3694 | 0.0000 | |
| GSE26886 | TRAM1 | 23471 | 201398_s_at | -0.3194 | 0.1736 | |
| GSE29001 | TRAM1 | 23471 | 201398_s_at | 0.1037 | 0.6846 | |
| GSE38129 | TRAM1 | 23471 | 201398_s_at | 0.1913 | 0.1147 | |
| GSE45670 | TRAM1 | 23471 | 201398_s_at | 0.1264 | 0.2994 | |
| GSE53622 | TRAM1 | 23471 | 118130 | 0.2540 | 0.0000 | |
| GSE53624 | TRAM1 | 23471 | 118130 | 0.1554 | 0.0072 | |
| GSE63941 | TRAM1 | 23471 | 201398_s_at | -1.4673 | 0.0022 | |
| GSE77861 | TRAM1 | 23471 | 201398_s_at | -0.0529 | 0.7630 | |
| GSE97050 | TRAM1 | 23471 | A_23_P112135 | 0.4630 | 0.1782 | |
| SRP007169 | TRAM1 | 23471 | RNAseq | -0.7860 | 0.0062 | |
| SRP008496 | TRAM1 | 23471 | RNAseq | -0.5239 | 0.0175 | |
| SRP064894 | TRAM1 | 23471 | RNAseq | 0.6286 | 0.0058 | |
| SRP133303 | TRAM1 | 23471 | RNAseq | 0.5726 | 0.0012 | |
| SRP159526 | TRAM1 | 23471 | RNAseq | 0.0125 | 0.9617 | |
| SRP193095 | TRAM1 | 23471 | RNAseq | -0.0784 | 0.5984 | |
| SRP219564 | TRAM1 | 23471 | RNAseq | 0.0659 | 0.7700 | |
| TCGA | TRAM1 | 23471 | RNAseq | -0.0699 | 0.0843 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TRAM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRAM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRAM1 | 23471 | 15 | 1 | 14 | |
| GSE20123 | TRAM1 | 23471 | 16 | 1 | 13 | |
| GSE43470 | TRAM1 | 23471 | 18 | 1 | 24 | |
| GSE46452 | TRAM1 | 23471 | 20 | 2 | 37 | |
| GSE47630 | TRAM1 | 23471 | 23 | 1 | 16 | |
| GSE54993 | TRAM1 | 23471 | 0 | 19 | 51 | |
| GSE54994 | TRAM1 | 23471 | 30 | 0 | 23 | |
| GSE60625 | TRAM1 | 23471 | 0 | 4 | 7 | |
| GSE74703 | TRAM1 | 23471 | 15 | 1 | 20 | |
| GSE74704 | TRAM1 | 23471 | 11 | 0 | 9 | |
| TCGA | TRAM1 | 23471 | 51 | 2 | 43 |
Total number of gains: 199; Total number of losses: 32; Total Number of normals: 257.
Somatic mutations of TRAM1:
Generating mutation plots.
Highly correlated genes for TRAM1:
Showing top 20/470 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRAM1 | PSMD8 | 0.734021 | 3 | 0 | 3 |
| TRAM1 | B3GALT6 | 0.733138 | 4 | 0 | 4 |
| TRAM1 | SLC17A5 | 0.708735 | 4 | 0 | 3 |
| TRAM1 | GYS1 | 0.705411 | 3 | 0 | 3 |
| TRAM1 | ZNF551 | 0.700433 | 3 | 0 | 3 |
| TRAM1 | CERKL | 0.693151 | 3 | 0 | 3 |
| TRAM1 | ABHD16A | 0.688007 | 3 | 0 | 3 |
| TRAM1 | RFTN1 | 0.685398 | 3 | 0 | 3 |
| TRAM1 | SETD7 | 0.684307 | 3 | 0 | 3 |
| TRAM1 | EI24 | 0.683671 | 5 | 0 | 4 |
| TRAM1 | PARVG | 0.675643 | 3 | 0 | 3 |
| TRAM1 | GBP5 | 0.670742 | 3 | 0 | 3 |
| TRAM1 | DDX21 | 0.669567 | 4 | 0 | 4 |
| TRAM1 | ABCA1 | 0.667639 | 4 | 0 | 3 |
| TRAM1 | CSTF3 | 0.665437 | 3 | 0 | 3 |
| TRAM1 | TMEM60 | 0.663517 | 3 | 0 | 3 |
| TRAM1 | LIPT1 | 0.660611 | 4 | 0 | 4 |
| TRAM1 | LAMP2 | 0.659179 | 3 | 0 | 3 |
| TRAM1 | UXS1 | 0.655317 | 6 | 0 | 4 |
| TRAM1 | BMPR2 | 0.654739 | 5 | 0 | 4 |
For details and further investigation, click here
