| Full name: TLR4 interactor with leucine rich repeats | Alias Symbol: KIAA0644 | ||
| Type: protein-coding gene | Cytoband: 7p14.3 | ||
| Entrez ID: 9865 | HGNC ID: HGNC:22200 | Ensembl Gene: ENSG00000255690 | OMIM ID: 613356 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIL | 9865 | 205151_s_at | 0.0918 | 0.9239 | |
| GSE20347 | TRIL | 9865 | 205151_s_at | -0.0265 | 0.9002 | |
| GSE23400 | TRIL | 9865 | 205151_s_at | -0.1993 | 0.0000 | |
| GSE26886 | TRIL | 9865 | 205151_s_at | -0.6579 | 0.0281 | |
| GSE29001 | TRIL | 9865 | 205151_s_at | -0.2131 | 0.3088 | |
| GSE38129 | TRIL | 9865 | 205151_s_at | -0.1994 | 0.1994 | |
| GSE45670 | TRIL | 9865 | 205151_s_at | -0.4200 | 0.2043 | |
| GSE53622 | TRIL | 9865 | 136342 | -0.4076 | 0.0429 | |
| GSE53624 | TRIL | 9865 | 136342 | -0.5854 | 0.0003 | |
| GSE63941 | TRIL | 9865 | 205151_s_at | -0.7049 | 0.0079 | |
| GSE77861 | TRIL | 9865 | 205151_s_at | -0.3542 | 0.0435 | |
| GSE97050 | TRIL | 9865 | A_24_P183664 | 0.1753 | 0.5782 | |
| SRP064894 | TRIL | 9865 | RNAseq | -0.3772 | 0.2455 | |
| SRP133303 | TRIL | 9865 | RNAseq | -1.1133 | 0.0000 | |
| SRP159526 | TRIL | 9865 | RNAseq | 0.2019 | 0.7053 | |
| SRP193095 | TRIL | 9865 | RNAseq | -0.1513 | 0.6308 | |
| SRP219564 | TRIL | 9865 | RNAseq | 0.3662 | 0.5496 | |
| TCGA | TRIL | 9865 | RNAseq | 0.0561 | 0.7666 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TRIL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIL | 9865 | 16 | 0 | 14 | |
| GSE20123 | TRIL | 9865 | 16 | 0 | 14 | |
| GSE43470 | TRIL | 9865 | 4 | 0 | 39 | |
| GSE46452 | TRIL | 9865 | 11 | 1 | 47 | |
| GSE47630 | TRIL | 9865 | 8 | 1 | 31 | |
| GSE54993 | TRIL | 9865 | 0 | 6 | 64 | |
| GSE54994 | TRIL | 9865 | 20 | 2 | 31 | |
| GSE60625 | TRIL | 9865 | 0 | 0 | 11 | |
| GSE74703 | TRIL | 9865 | 4 | 0 | 32 | |
| GSE74704 | TRIL | 9865 | 10 | 0 | 10 | |
| TCGA | TRIL | 9865 | 54 | 7 | 35 |
Total number of gains: 143; Total number of losses: 17; Total Number of normals: 328.
Somatic mutations of TRIL:
Generating mutation plots.
Highly correlated genes for TRIL:
Showing top 20/54 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIL | CAPN13 | 0.709905 | 3 | 0 | 3 |
| TRIL | DOCK10 | 0.609208 | 3 | 0 | 3 |
| TRIL | TRG-AS1 | 0.588907 | 4 | 0 | 3 |
| TRIL | HCG27 | 0.58573 | 4 | 0 | 3 |
| TRIL | ADAMDEC1 | 0.583109 | 4 | 0 | 3 |
| TRIL | FMO2 | 0.578319 | 4 | 0 | 3 |
| TRIL | KCNJ5 | 0.574295 | 3 | 0 | 3 |
| TRIL | THEMIS | 0.568353 | 5 | 0 | 4 |
| TRIL | NLRC3 | 0.564928 | 7 | 0 | 4 |
| TRIL | ZNF831 | 0.564002 | 5 | 0 | 4 |
| TRIL | FUCA1 | 0.559653 | 7 | 0 | 4 |
| TRIL | GPR34 | 0.559159 | 4 | 0 | 4 |
| TRIL | DNAJC5 | 0.557937 | 3 | 0 | 3 |
| TRIL | PITX1 | 0.553763 | 4 | 0 | 3 |
| TRIL | CCR5 | 0.553055 | 5 | 0 | 3 |
| TRIL | SELENBP1 | 0.552238 | 6 | 0 | 3 |
| TRIL | FMO4 | 0.550326 | 6 | 0 | 3 |
| TRIL | SIDT1 | 0.550228 | 5 | 0 | 3 |
| TRIL | EVI2B | 0.549827 | 5 | 0 | 4 |
| TRIL | PABPC3 | 0.543837 | 4 | 0 | 3 |
For details and further investigation, click here
