TRIM7

 

Full name: tripartite motif containing 7 Alias Symbol: RNF90|GNIP
Type: protein-coding gene Cytoband: 5q35.3
Entrez ID: 81786 HGNC ID: HGNC:16278 Ensembl Gene: ENSG00000146054 OMIM ID: 609315
Drug and gene relationship at DGIdb

 

Expression of TRIM7:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TRIM7 81786 223694_at -0.8625 0.2982
GSE26886 TRIM7 81786 223694_at -0.7919 0.0105
GSE45670 TRIM7 81786 223694_at -0.1202 0.6555
GSE53622 TRIM7 81786 37463 -0.9528 0.0000
GSE53624 TRIM7 81786 37463 -1.2441 0.0000
GSE63941 TRIM7 81786 223694_at 2.0233 0.0039
GSE77861 TRIM7 81786 223694_at -0.0208 0.9563
GSE97050 TRIM7 81786 A_24_P277615 -0.6014 0.1181
SRP007169 TRIM7 81786 RNAseq -1.0459 0.1017
SRP008496 TRIM7 81786 RNAseq -1.2962 0.0814
SRP064894 TRIM7 81786 RNAseq -1.2040 0.0002
SRP133303 TRIM7 81786 RNAseq -1.0324 0.0003
SRP159526 TRIM7 81786 RNAseq -0.9280 0.2558
SRP193095 TRIM7 81786 RNAseq -0.7579 0.0045
SRP219564 TRIM7 81786 RNAseq -1.7990 0.0012
TCGA TRIM7 81786 RNAseq 0.6065 0.0006

Upregulated datasets: 1; Downregulated datasets: 4.  


 

Survival by TRIM7 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TRIM7:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TRIM7 81786 2 13 15
GSE20123 TRIM7 81786 2 13 15
GSE43470 TRIM7 81786 1 10 32
GSE46452 TRIM7 81786 0 27 32
GSE47630 TRIM7 81786 2 20 18
GSE54993 TRIM7 81786 10 2 58
GSE54994 TRIM7 81786 3 19 31
GSE60625 TRIM7 81786 1 0 10
GSE74703 TRIM7 81786 1 6 29
GSE74704 TRIM7 81786 1 6 13
TCGA TRIM7 81786 12 33 51

Total number of gains: 35; Total number of losses: 149; Total Number of normals: 304.  


 

Somatic mutations of TRIM7:

 

Generating mutation plots.

 

Highly correlated genes for TRIM7:

 

Showing top 20/822 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TRIM7RETSAT0.783869303
TRIM7CCNYL10.742007303
TRIM7EPGN0.719535303
TRIM7NUAK20.707271303
TRIM7KIAA15220.701715303
TRIM7LGALS30.701161303
TRIM7ZBTB8OS0.701013303
TRIM7CKMT1A0.697012303
TRIM7USP430.694562505
TRIM7DSG10.692599303
TRIM7RNF1410.689193404
TRIM7PGLYRP30.687458303
TRIM7RTCA0.686468303
TRIM7RNF144B0.686161303
TRIM7FAM110C0.684399606
TRIM7C19orf330.681754605
TRIM7BNIPL0.679561505
TRIM7SGPP20.675389605
TRIM7THAP20.675268303
TRIM7WDR470.671691303

For details and further investigation, click here