| Full name: tetraspanin 4 | Alias Symbol: NAG-2|TSPAN-4|TETRASPAN | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 7106 | HGNC ID: HGNC:11859 | Ensembl Gene: ENSG00000214063 | OMIM ID: 602644 |
| Drug and gene relationship at DGIdb | |||
Expression of TSPAN4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSPAN4 | 7106 | 209263_x_at | -0.1356 | 0.8117 | |
| GSE20347 | TSPAN4 | 7106 | 209263_x_at | 0.1719 | 0.1053 | |
| GSE23400 | TSPAN4 | 7106 | 209263_x_at | 0.0124 | 0.8983 | |
| GSE26886 | TSPAN4 | 7106 | 209263_x_at | 0.8294 | 0.0020 | |
| GSE29001 | TSPAN4 | 7106 | 209263_x_at | 0.1905 | 0.4881 | |
| GSE38129 | TSPAN4 | 7106 | 209263_x_at | -0.0487 | 0.8457 | |
| GSE45670 | TSPAN4 | 7106 | 209263_x_at | -0.6974 | 0.0106 | |
| GSE53622 | TSPAN4 | 7106 | 37017 | -0.1140 | 0.4085 | |
| GSE53624 | TSPAN4 | 7106 | 37017 | 0.1137 | 0.3908 | |
| GSE63941 | TSPAN4 | 7106 | 209263_x_at | -1.8698 | 0.0066 | |
| GSE77861 | TSPAN4 | 7106 | 209263_x_at | 0.1397 | 0.3673 | |
| GSE97050 | TSPAN4 | 7106 | A_23_P316741 | -0.2964 | 0.3924 | |
| SRP007169 | TSPAN4 | 7106 | RNAseq | 1.0038 | 0.1045 | |
| SRP008496 | TSPAN4 | 7106 | RNAseq | 1.1800 | 0.0067 | |
| SRP064894 | TSPAN4 | 7106 | RNAseq | 0.5572 | 0.1614 | |
| SRP133303 | TSPAN4 | 7106 | RNAseq | -0.1507 | 0.5846 | |
| SRP159526 | TSPAN4 | 7106 | RNAseq | -0.0620 | 0.8355 | |
| SRP193095 | TSPAN4 | 7106 | RNAseq | 0.8233 | 0.0000 | |
| SRP219564 | TSPAN4 | 7106 | RNAseq | -0.0435 | 0.9507 | |
| TCGA | TSPAN4 | 7106 | RNAseq | -0.0597 | 0.5627 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by TSPAN4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TSPAN4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSPAN4 | 7106 | 1 | 11 | 18 | |
| GSE20123 | TSPAN4 | 7106 | 1 | 12 | 17 | |
| GSE43470 | TSPAN4 | 7106 | 1 | 10 | 32 | |
| GSE46452 | TSPAN4 | 7106 | 7 | 8 | 44 | |
| GSE47630 | TSPAN4 | 7106 | 4 | 12 | 24 | |
| GSE54993 | TSPAN4 | 7106 | 3 | 1 | 66 | |
| GSE54994 | TSPAN4 | 7106 | 1 | 12 | 40 | |
| GSE60625 | TSPAN4 | 7106 | 0 | 0 | 11 | |
| GSE74703 | TSPAN4 | 7106 | 1 | 8 | 27 | |
| GSE74704 | TSPAN4 | 7106 | 0 | 8 | 12 | |
| TCGA | TSPAN4 | 7106 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 120; Total Number of normals: 341.
Somatic mutations of TSPAN4:
Generating mutation plots.
Highly correlated genes for TSPAN4:
Showing top 20/1030 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSPAN4 | TNFSF12 | 0.777705 | 3 | 0 | 3 |
| TSPAN4 | JMY | 0.769751 | 3 | 0 | 3 |
| TSPAN4 | GNG2 | 0.755917 | 5 | 0 | 5 |
| TSPAN4 | TYW3 | 0.738825 | 3 | 0 | 3 |
| TSPAN4 | PMP22 | 0.732271 | 11 | 0 | 10 |
| TSPAN4 | ANXA6 | 0.727022 | 11 | 0 | 10 |
| TSPAN4 | VSTM4 | 0.723572 | 10 | 0 | 10 |
| TSPAN4 | BICC1 | 0.722463 | 10 | 0 | 8 |
| TSPAN4 | DAB2 | 0.717991 | 12 | 0 | 11 |
| TSPAN4 | GIMAP5 | 0.708623 | 3 | 0 | 3 |
| TSPAN4 | FBN1 | 0.708047 | 10 | 0 | 9 |
| TSPAN4 | EPDR1 | 0.70321 | 6 | 0 | 6 |
| TSPAN4 | CCDC80 | 0.702581 | 7 | 0 | 7 |
| TSPAN4 | GNG11 | 0.702474 | 10 | 0 | 10 |
| TSPAN4 | MYOM2 | 0.701793 | 3 | 0 | 3 |
| TSPAN4 | KANK2 | 0.699342 | 9 | 0 | 9 |
| TSPAN4 | PTPRM | 0.699116 | 12 | 0 | 11 |
| TSPAN4 | RARRES2 | 0.697932 | 11 | 0 | 10 |
| TSPAN4 | SVEP1 | 0.697298 | 8 | 0 | 7 |
| TSPAN4 | CD34 | 0.696968 | 6 | 0 | 5 |
For details and further investigation, click here
