| Full name: testis specific serine kinase 1B | Alias Symbol: SPOGA4|FKSG81 | ||
| Type: protein-coding gene | Cytoband: 5q22.2 | ||
| Entrez ID: 83942 | HGNC ID: HGNC:14968 | Ensembl Gene: ENSG00000212122 | OMIM ID: 610709 |
| Drug and gene relationship at DGIdb | |||
Expression of TSSK1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSSK1B | 83942 | 211694_at | -0.0671 | 0.7567 | |
| GSE20347 | TSSK1B | 83942 | 211694_at | -0.0304 | 0.6205 | |
| GSE23400 | TSSK1B | 83942 | 211694_at | -0.1291 | 0.0000 | |
| GSE26886 | TSSK1B | 83942 | 211694_at | 0.0298 | 0.8630 | |
| GSE29001 | TSSK1B | 83942 | 211694_at | -0.1345 | 0.2442 | |
| GSE38129 | TSSK1B | 83942 | 211694_at | -0.0299 | 0.6170 | |
| GSE45670 | TSSK1B | 83942 | 211694_at | -0.0393 | 0.6928 | |
| GSE63941 | TSSK1B | 83942 | 211694_at | 0.0120 | 0.9411 | |
| GSE77861 | TSSK1B | 83942 | 211694_at | -0.0982 | 0.2751 | |
| GSE97050 | TSSK1B | 83942 | A_23_P427136 | 0.0311 | 0.8892 | |
| SRP133303 | TSSK1B | 83942 | RNAseq | 0.0933 | 0.8007 | |
| TCGA | TSSK1B | 83942 | RNAseq | 1.7269 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TSSK1B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TSSK1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSSK1B | 83942 | 1 | 13 | 16 | |
| GSE20123 | TSSK1B | 83942 | 1 | 13 | 16 | |
| GSE43470 | TSSK1B | 83942 | 3 | 9 | 31 | |
| GSE46452 | TSSK1B | 83942 | 0 | 28 | 31 | |
| GSE47630 | TSSK1B | 83942 | 0 | 21 | 19 | |
| GSE54993 | TSSK1B | 83942 | 9 | 1 | 60 | |
| GSE54994 | TSSK1B | 83942 | 1 | 17 | 35 | |
| GSE60625 | TSSK1B | 83942 | 0 | 0 | 11 | |
| GSE74703 | TSSK1B | 83942 | 2 | 7 | 27 | |
| GSE74704 | TSSK1B | 83942 | 1 | 7 | 12 | |
| TCGA | TSSK1B | 83942 | 2 | 41 | 53 |
Total number of gains: 20; Total number of losses: 157; Total Number of normals: 311.
Somatic mutations of TSSK1B:
Generating mutation plots.
Highly correlated genes for TSSK1B:
Showing top 20/224 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSSK1B | LDOC1 | 0.714488 | 3 | 0 | 3 |
| TSSK1B | MMP25 | 0.675258 | 3 | 0 | 3 |
| TSSK1B | PPP1R9A | 0.666975 | 3 | 0 | 3 |
| TSSK1B | CLDN11 | 0.65844 | 3 | 0 | 3 |
| TSSK1B | CASZ1 | 0.656994 | 4 | 0 | 4 |
| TSSK1B | CASKIN2 | 0.653905 | 3 | 0 | 3 |
| TSSK1B | DAGLA | 0.646897 | 3 | 0 | 3 |
| TSSK1B | NPAP1 | 0.643036 | 3 | 0 | 3 |
| TSSK1B | ADH1B | 0.636733 | 3 | 0 | 3 |
| TSSK1B | IFNA10 | 0.635467 | 4 | 0 | 4 |
| TSSK1B | ZNF619 | 0.634743 | 3 | 0 | 3 |
| TSSK1B | TGM4 | 0.627832 | 4 | 0 | 3 |
| TSSK1B | PTPN5 | 0.624368 | 4 | 0 | 4 |
| TSSK1B | ASPA | 0.623166 | 3 | 0 | 3 |
| TSSK1B | SLC4A4 | 0.620939 | 4 | 0 | 3 |
| TSSK1B | PCSK2 | 0.618027 | 4 | 0 | 4 |
| TSSK1B | RS1 | 0.615687 | 4 | 0 | 3 |
| TSSK1B | CYP4V2 | 0.615638 | 3 | 0 | 3 |
| TSSK1B | ZNF717 | 0.609801 | 4 | 0 | 4 |
| TSSK1B | RNF125 | 0.608285 | 3 | 0 | 3 |
For details and further investigation, click here
