| Full name: CNKSR family member 3 | Alias Symbol: FLJ31349 | ||
| Type: protein-coding gene | Cytoband: 6q25.2 | ||
| Entrez ID: 154043 | HGNC ID: HGNC:23034 | Ensembl Gene: ENSG00000153721 | OMIM ID: 617476 |
| Drug and gene relationship at DGIdb | |||
Expression of CNKSR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNKSR3 | 154043 | 227481_at | -0.8635 | 0.1557 | |
| GSE26886 | CNKSR3 | 154043 | 227481_at | -1.9647 | 0.0000 | |
| GSE45670 | CNKSR3 | 154043 | 227481_at | -0.8240 | 0.0023 | |
| GSE53622 | CNKSR3 | 154043 | 56550 | -1.2260 | 0.0000 | |
| GSE53624 | CNKSR3 | 154043 | 56550 | -1.2590 | 0.0000 | |
| GSE63941 | CNKSR3 | 154043 | 227481_at | -1.3320 | 0.1727 | |
| GSE77861 | CNKSR3 | 154043 | 227481_at | -0.5156 | 0.3811 | |
| GSE97050 | CNKSR3 | 154043 | A_33_P3368646 | -0.8090 | 0.0786 | |
| SRP007169 | CNKSR3 | 154043 | RNAseq | -2.2381 | 0.0000 | |
| SRP008496 | CNKSR3 | 154043 | RNAseq | -2.0167 | 0.0000 | |
| SRP064894 | CNKSR3 | 154043 | RNAseq | -1.8406 | 0.0000 | |
| SRP133303 | CNKSR3 | 154043 | RNAseq | -1.0911 | 0.0002 | |
| SRP159526 | CNKSR3 | 154043 | RNAseq | -0.3350 | 0.4885 | |
| SRP193095 | CNKSR3 | 154043 | RNAseq | -1.2830 | 0.0000 | |
| SRP219564 | CNKSR3 | 154043 | RNAseq | -1.0801 | 0.0434 | |
| TCGA | CNKSR3 | 154043 | RNAseq | -0.2765 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by CNKSR3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNKSR3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNKSR3 | 154043 | 1 | 4 | 25 | |
| GSE20123 | CNKSR3 | 154043 | 1 | 3 | 26 | |
| GSE43470 | CNKSR3 | 154043 | 4 | 0 | 39 | |
| GSE46452 | CNKSR3 | 154043 | 3 | 10 | 46 | |
| GSE47630 | CNKSR3 | 154043 | 9 | 4 | 27 | |
| GSE54993 | CNKSR3 | 154043 | 3 | 2 | 65 | |
| GSE54994 | CNKSR3 | 154043 | 8 | 8 | 37 | |
| GSE60625 | CNKSR3 | 154043 | 0 | 1 | 10 | |
| GSE74703 | CNKSR3 | 154043 | 4 | 0 | 32 | |
| GSE74704 | CNKSR3 | 154043 | 0 | 1 | 19 | |
| TCGA | CNKSR3 | 154043 | 12 | 21 | 63 |
Total number of gains: 45; Total number of losses: 54; Total Number of normals: 389.
Somatic mutations of CNKSR3:
Generating mutation plots.
Highly correlated genes for CNKSR3:
Showing top 20/1119 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNKSR3 | ZNF330 | 0.755096 | 3 | 0 | 3 |
| CNKSR3 | CAB39L | 0.752789 | 7 | 0 | 7 |
| CNKSR3 | RORA | 0.742587 | 6 | 0 | 6 |
| CNKSR3 | WDR26 | 0.736173 | 6 | 0 | 6 |
| CNKSR3 | STK39 | 0.730376 | 7 | 0 | 7 |
| CNKSR3 | MXI1 | 0.730246 | 7 | 0 | 6 |
| CNKSR3 | PAX9 | 0.727514 | 5 | 0 | 5 |
| CNKSR3 | DEGS2 | 0.716402 | 5 | 0 | 5 |
| CNKSR3 | SMIM5 | 0.713522 | 6 | 0 | 6 |
| CNKSR3 | SECISBP2L | 0.710741 | 7 | 0 | 6 |
| CNKSR3 | CIPC | 0.707994 | 6 | 0 | 6 |
| CNKSR3 | PELI1 | 0.704937 | 7 | 0 | 6 |
| CNKSR3 | NFIX | 0.70208 | 5 | 0 | 5 |
| CNKSR3 | TEAD3 | 0.700774 | 4 | 0 | 4 |
| CNKSR3 | KIF21A | 0.70024 | 4 | 0 | 4 |
| CNKSR3 | KAT2B | 0.69971 | 7 | 0 | 7 |
| CNKSR3 | CHP1 | 0.698694 | 5 | 0 | 5 |
| CNKSR3 | LMO7 | 0.698521 | 6 | 0 | 6 |
| CNKSR3 | KDM3B | 0.697929 | 3 | 0 | 3 |
| CNKSR3 | YY1AP1 | 0.695088 | 5 | 0 | 5 |
For details and further investigation, click here
