| Full name: UL16 binding protein 1 | Alias Symbol: RAET1I | ||
| Type: protein-coding gene | Cytoband: 6q25.1 | ||
| Entrez ID: 80329 | HGNC ID: HGNC:14893 | Ensembl Gene: ENSG00000111981 | OMIM ID: 605697 |
| Drug and gene relationship at DGIdb | |||
ULBP1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04650 | Natural killer cell mediated cytotoxicity |
Expression of ULBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ULBP1 | 80329 | 221323_at | 0.0071 | 0.9883 | |
| GSE20347 | ULBP1 | 80329 | 221323_at | -0.1059 | 0.1291 | |
| GSE23400 | ULBP1 | 80329 | 221323_at | -0.1717 | 0.0003 | |
| GSE26886 | ULBP1 | 80329 | 221323_at | 0.0161 | 0.9021 | |
| GSE29001 | ULBP1 | 80329 | 221323_at | -0.1031 | 0.5634 | |
| GSE38129 | ULBP1 | 80329 | 221323_at | -0.1293 | 0.0735 | |
| GSE45670 | ULBP1 | 80329 | 221323_at | 0.1003 | 0.2764 | |
| GSE53622 | ULBP1 | 80329 | 20838 | 1.6492 | 0.0000 | |
| GSE53624 | ULBP1 | 80329 | 20838 | 2.0211 | 0.0000 | |
| GSE63941 | ULBP1 | 80329 | 221323_at | 0.6379 | 0.2159 | |
| GSE77861 | ULBP1 | 80329 | 221323_at | -0.2708 | 0.0563 | |
| GSE97050 | ULBP1 | 80329 | A_33_P3422802 | 0.6778 | 0.1204 | |
| SRP007169 | ULBP1 | 80329 | RNAseq | 4.4768 | 0.0002 | |
| SRP133303 | ULBP1 | 80329 | RNAseq | 1.3466 | 0.0000 | |
| SRP159526 | ULBP1 | 80329 | RNAseq | 3.2924 | 0.0000 | |
| SRP193095 | ULBP1 | 80329 | RNAseq | 1.0970 | 0.0000 | |
| SRP219564 | ULBP1 | 80329 | RNAseq | 1.6535 | 0.0160 | |
| TCGA | ULBP1 | 80329 | RNAseq | 3.0992 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by ULBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ULBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ULBP1 | 80329 | 2 | 4 | 24 | |
| GSE20123 | ULBP1 | 80329 | 2 | 3 | 25 | |
| GSE43470 | ULBP1 | 80329 | 4 | 0 | 39 | |
| GSE46452 | ULBP1 | 80329 | 3 | 10 | 46 | |
| GSE47630 | ULBP1 | 80329 | 9 | 4 | 27 | |
| GSE54993 | ULBP1 | 80329 | 3 | 2 | 65 | |
| GSE54994 | ULBP1 | 80329 | 8 | 8 | 37 | |
| GSE60625 | ULBP1 | 80329 | 0 | 1 | 10 | |
| GSE74703 | ULBP1 | 80329 | 4 | 0 | 32 | |
| GSE74704 | ULBP1 | 80329 | 0 | 1 | 19 | |
| TCGA | ULBP1 | 80329 | 11 | 22 | 63 |
Total number of gains: 46; Total number of losses: 55; Total Number of normals: 387.
Somatic mutations of ULBP1:
Generating mutation plots.
Highly correlated genes for ULBP1:
Showing top 20/608 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ULBP1 | DRD5 | 0.695724 | 3 | 0 | 3 |
| ULBP1 | C19orf48 | 0.688406 | 3 | 0 | 3 |
| ULBP1 | IL9 | 0.681918 | 4 | 0 | 4 |
| ULBP1 | GPRIN1 | 0.681549 | 3 | 0 | 3 |
| ULBP1 | TCP10L | 0.675489 | 4 | 0 | 4 |
| ULBP1 | E2F7 | 0.674987 | 3 | 0 | 3 |
| ULBP1 | SDS | 0.671686 | 3 | 0 | 3 |
| ULBP1 | BOP1 | 0.669869 | 3 | 0 | 3 |
| ULBP1 | KRTAP4-7 | 0.664738 | 4 | 0 | 3 |
| ULBP1 | PLEKHG4B | 0.662604 | 3 | 0 | 3 |
| ULBP1 | IL19 | 0.660043 | 4 | 0 | 3 |
| ULBP1 | NR5A1 | 0.65777 | 5 | 0 | 5 |
| ULBP1 | GIP | 0.657349 | 3 | 0 | 3 |
| ULBP1 | CD79A | 0.656004 | 3 | 0 | 3 |
| ULBP1 | CLDN9 | 0.651828 | 6 | 0 | 5 |
| ULBP1 | EPS8L3 | 0.650887 | 5 | 0 | 3 |
| ULBP1 | NPAP1 | 0.650297 | 4 | 0 | 3 |
| ULBP1 | IFNA10 | 0.648673 | 5 | 0 | 3 |
| ULBP1 | KIR2DS5 | 0.646461 | 5 | 0 | 4 |
| ULBP1 | PHLDB1 | 0.644047 | 6 | 0 | 5 |
For details and further investigation, click here
