| Full name: VPS37D subunit of ESCRT-I | Alias Symbol: MGC35352 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 155382 | HGNC ID: HGNC:18287 | Ensembl Gene: ENSG00000176428 | OMIM ID: 610039 |
| Drug and gene relationship at DGIdb | |||
Expression of VPS37D:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VPS37D | 155382 | 235569_at | 0.0911 | 0.7000 | |
| GSE26886 | VPS37D | 155382 | 235569_at | 0.4817 | 0.0033 | |
| GSE45670 | VPS37D | 155382 | 235569_at | 0.1002 | 0.3259 | |
| GSE53622 | VPS37D | 155382 | 44538 | 0.6300 | 0.0000 | |
| GSE53624 | VPS37D | 155382 | 44538 | 0.7184 | 0.0000 | |
| GSE63941 | VPS37D | 155382 | 235569_at | -0.2315 | 0.3417 | |
| GSE77861 | VPS37D | 155382 | 235569_at | 0.1644 | 0.1645 | |
| GSE97050 | VPS37D | 155382 | A_33_P3293573 | -0.1192 | 0.7028 | |
| SRP007169 | VPS37D | 155382 | RNAseq | 2.9546 | 0.0219 | |
| SRP133303 | VPS37D | 155382 | RNAseq | 0.3331 | 0.1951 | |
| SRP159526 | VPS37D | 155382 | RNAseq | 2.5298 | 0.0000 | |
| SRP219564 | VPS37D | 155382 | RNAseq | 0.5713 | 0.3646 | |
| TCGA | VPS37D | 155382 | RNAseq | 0.2850 | 0.2387 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by VPS37D expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VPS37D:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VPS37D | 155382 | 14 | 1 | 15 | |
| GSE20123 | VPS37D | 155382 | 14 | 1 | 15 | |
| GSE43470 | VPS37D | 155382 | 3 | 2 | 38 | |
| GSE46452 | VPS37D | 155382 | 12 | 0 | 47 | |
| GSE47630 | VPS37D | 155382 | 7 | 2 | 31 | |
| GSE54993 | VPS37D | 155382 | 2 | 7 | 61 | |
| GSE54994 | VPS37D | 155382 | 14 | 3 | 36 | |
| GSE60625 | VPS37D | 155382 | 0 | 0 | 11 | |
| GSE74703 | VPS37D | 155382 | 3 | 1 | 32 | |
| GSE74704 | VPS37D | 155382 | 8 | 1 | 11 | |
| TCGA | VPS37D | 155382 | 45 | 7 | 44 |
Total number of gains: 122; Total number of losses: 25; Total Number of normals: 341.
Somatic mutations of VPS37D:
Generating mutation plots.
Highly correlated genes for VPS37D:
Showing top 20/89 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VPS37D | ATXN7L2 | 0.664843 | 3 | 0 | 3 |
| VPS37D | GNB1L | 0.663488 | 4 | 0 | 4 |
| VPS37D | NACAD | 0.65234 | 3 | 0 | 3 |
| VPS37D | SCN1B | 0.633215 | 3 | 0 | 3 |
| VPS37D | FZD9 | 0.6297 | 4 | 0 | 4 |
| VPS37D | CD320 | 0.627768 | 4 | 0 | 3 |
| VPS37D | STMN3 | 0.62761 | 3 | 0 | 3 |
| VPS37D | BTG4 | 0.627549 | 3 | 0 | 3 |
| VPS37D | DOK7 | 0.627307 | 3 | 0 | 3 |
| VPS37D | ATP8A2 | 0.626475 | 4 | 0 | 4 |
| VPS37D | MSI1 | 0.625706 | 3 | 0 | 3 |
| VPS37D | UPK3A | 0.622714 | 3 | 0 | 3 |
| VPS37D | KXD1 | 0.614983 | 3 | 0 | 3 |
| VPS37D | TNNC2 | 0.613547 | 3 | 0 | 3 |
| VPS37D | ASTN2 | 0.608873 | 5 | 0 | 3 |
| VPS37D | IFT27 | 0.608142 | 3 | 0 | 3 |
| VPS37D | KCNQ5 | 0.605936 | 3 | 0 | 3 |
| VPS37D | SLC29A4 | 0.604684 | 6 | 0 | 5 |
| VPS37D | ZNF511 | 0.602749 | 3 | 0 | 3 |
| VPS37D | SLC6A13 | 0.602185 | 3 | 0 | 3 |
For details and further investigation, click here
