| Full name: YKT6 v-SNARE homolog | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p13 | ||
| Entrez ID: 10652 | HGNC ID: HGNC:16959 | Ensembl Gene: ENSG00000106636 | OMIM ID: 606209 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of YKT6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | YKT6 | 10652 | 217784_at | 0.8284 | 0.0616 | |
| GSE20347 | YKT6 | 10652 | 217784_at | 0.3973 | 0.0118 | |
| GSE23400 | YKT6 | 10652 | 217784_at | 0.3849 | 0.0000 | |
| GSE26886 | YKT6 | 10652 | 217784_at | 0.1904 | 0.3580 | |
| GSE29001 | YKT6 | 10652 | 217784_at | 0.3580 | 0.1330 | |
| GSE38129 | YKT6 | 10652 | 217784_at | 0.5846 | 0.0000 | |
| GSE45670 | YKT6 | 10652 | 217784_at | 0.5305 | 0.0029 | |
| GSE53622 | YKT6 | 10652 | 163313 | -0.2708 | 0.0064 | |
| GSE53624 | YKT6 | 10652 | 163313 | -0.0753 | 0.3233 | |
| GSE63941 | YKT6 | 10652 | 217784_at | 0.2109 | 0.7191 | |
| GSE77861 | YKT6 | 10652 | 217784_at | 0.2719 | 0.0914 | |
| GSE97050 | YKT6 | 10652 | A_24_P372048 | -0.1375 | 0.7212 | |
| SRP007169 | YKT6 | 10652 | RNAseq | -0.3999 | 0.1820 | |
| SRP008496 | YKT6 | 10652 | RNAseq | 0.1262 | 0.6019 | |
| SRP064894 | YKT6 | 10652 | RNAseq | 0.3900 | 0.0269 | |
| SRP133303 | YKT6 | 10652 | RNAseq | 0.6478 | 0.0006 | |
| SRP159526 | YKT6 | 10652 | RNAseq | 0.2341 | 0.3174 | |
| SRP193095 | YKT6 | 10652 | RNAseq | 0.1862 | 0.1962 | |
| SRP219564 | YKT6 | 10652 | RNAseq | 0.0098 | 0.9770 | |
| TCGA | YKT6 | 10652 | RNAseq | 0.0607 | 0.2325 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by YKT6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of YKT6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | YKT6 | 10652 | 14 | 0 | 16 | |
| GSE20123 | YKT6 | 10652 | 13 | 0 | 17 | |
| GSE43470 | YKT6 | 10652 | 4 | 0 | 39 | |
| GSE46452 | YKT6 | 10652 | 11 | 1 | 47 | |
| GSE47630 | YKT6 | 10652 | 8 | 1 | 31 | |
| GSE54993 | YKT6 | 10652 | 0 | 8 | 62 | |
| GSE54994 | YKT6 | 10652 | 17 | 3 | 33 | |
| GSE60625 | YKT6 | 10652 | 0 | 0 | 11 | |
| GSE74703 | YKT6 | 10652 | 4 | 0 | 32 | |
| GSE74704 | YKT6 | 10652 | 7 | 0 | 13 | |
| TCGA | YKT6 | 10652 | 51 | 7 | 38 |
Total number of gains: 129; Total number of losses: 20; Total Number of normals: 339.
Somatic mutations of YKT6:
Generating mutation plots.
Highly correlated genes for YKT6:
Showing top 20/834 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| YKT6 | BCL2L12 | 0.724343 | 3 | 0 | 3 |
| YKT6 | DCBLD1 | 0.717638 | 3 | 0 | 3 |
| YKT6 | NRM | 0.711312 | 3 | 0 | 3 |
| YKT6 | ARSI | 0.708006 | 3 | 0 | 3 |
| YKT6 | CKAP2L | 0.702975 | 3 | 0 | 3 |
| YKT6 | ZNF114 | 0.699944 | 3 | 0 | 3 |
| YKT6 | UHRF1 | 0.699661 | 3 | 0 | 3 |
| YKT6 | FEN1 | 0.695725 | 6 | 0 | 6 |
| YKT6 | ADRM1 | 0.689726 | 8 | 0 | 8 |
| YKT6 | CDCA5 | 0.689121 | 3 | 0 | 3 |
| YKT6 | LRR1 | 0.688922 | 3 | 0 | 3 |
| YKT6 | CDKN3 | 0.683783 | 6 | 0 | 6 |
| YKT6 | GINS2 | 0.680227 | 5 | 0 | 5 |
| YKT6 | DDX56 | 0.678032 | 9 | 0 | 8 |
| YKT6 | TTYH3 | 0.677941 | 4 | 0 | 4 |
| YKT6 | MMP10 | 0.672788 | 6 | 0 | 5 |
| YKT6 | KIF4A | 0.671821 | 6 | 0 | 5 |
| YKT6 | RTN4R | 0.670812 | 4 | 0 | 3 |
| YKT6 | SHCBP1 | 0.670801 | 6 | 0 | 6 |
| YKT6 | PTRH1 | 0.669522 | 4 | 0 | 4 |
For details and further investigation, click here
