| Full name: zinc finger DHHC-type containing 2 | Alias Symbol: ZNF372|DHHC2 | ||
| Type: protein-coding gene | Cytoband: 8p22 | ||
| Entrez ID: 51201 | HGNC ID: HGNC:18469 | Ensembl Gene: ENSG00000104219 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZDHHC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZDHHC2 | 51201 | 222731_at | -0.7633 | 0.4729 | |
| GSE26886 | ZDHHC2 | 51201 | 222730_s_at | 0.3202 | 0.5849 | |
| GSE45670 | ZDHHC2 | 51201 | 222731_at | -0.8959 | 0.1135 | |
| GSE53622 | ZDHHC2 | 51201 | 56773 | -0.8154 | 0.0000 | |
| GSE53624 | ZDHHC2 | 51201 | 56773 | -0.5682 | 0.0022 | |
| GSE63941 | ZDHHC2 | 51201 | 222731_at | -0.7415 | 0.3885 | |
| GSE77861 | ZDHHC2 | 51201 | 222730_s_at | 0.4637 | 0.4782 | |
| GSE97050 | ZDHHC2 | 51201 | A_33_P3267665 | -0.3821 | 0.2226 | |
| SRP007169 | ZDHHC2 | 51201 | RNAseq | 0.8941 | 0.0979 | |
| SRP008496 | ZDHHC2 | 51201 | RNAseq | 1.3091 | 0.0361 | |
| SRP064894 | ZDHHC2 | 51201 | RNAseq | -0.6780 | 0.0290 | |
| SRP133303 | ZDHHC2 | 51201 | RNAseq | -0.2037 | 0.5156 | |
| SRP159526 | ZDHHC2 | 51201 | RNAseq | 0.3659 | 0.5285 | |
| SRP193095 | ZDHHC2 | 51201 | RNAseq | 0.0562 | 0.8263 | |
| SRP219564 | ZDHHC2 | 51201 | RNAseq | -0.4846 | 0.4950 | |
| TCGA | ZDHHC2 | 51201 | RNAseq | -0.3390 | 0.0660 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZDHHC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZDHHC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZDHHC2 | 51201 | 3 | 11 | 16 | |
| GSE20123 | ZDHHC2 | 51201 | 4 | 11 | 15 | |
| GSE43470 | ZDHHC2 | 51201 | 4 | 8 | 31 | |
| GSE46452 | ZDHHC2 | 51201 | 14 | 13 | 32 | |
| GSE47630 | ZDHHC2 | 51201 | 10 | 8 | 22 | |
| GSE54993 | ZDHHC2 | 51201 | 2 | 14 | 54 | |
| GSE54994 | ZDHHC2 | 51201 | 8 | 18 | 27 | |
| GSE60625 | ZDHHC2 | 51201 | 3 | 0 | 8 | |
| GSE74703 | ZDHHC2 | 51201 | 4 | 7 | 25 | |
| GSE74704 | ZDHHC2 | 51201 | 3 | 7 | 10 | |
| TCGA | ZDHHC2 | 51201 | 14 | 40 | 42 |
Total number of gains: 69; Total number of losses: 137; Total Number of normals: 282.
Somatic mutations of ZDHHC2:
Generating mutation plots.
Highly correlated genes for ZDHHC2:
Showing top 20/105 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZDHHC2 | SORL1 | 0.768375 | 3 | 0 | 3 |
| ZDHHC2 | P4HTM | 0.719359 | 4 | 0 | 4 |
| ZDHHC2 | ZNF516 | 0.700511 | 4 | 0 | 4 |
| ZDHHC2 | CPA3 | 0.698735 | 3 | 0 | 3 |
| ZDHHC2 | AGGF1 | 0.687865 | 3 | 0 | 3 |
| ZDHHC2 | NFU1 | 0.68645 | 3 | 0 | 3 |
| ZDHHC2 | SLC16A6 | 0.683793 | 3 | 0 | 3 |
| ZDHHC2 | THYN1 | 0.682742 | 3 | 0 | 3 |
| ZDHHC2 | SEMA4A | 0.680488 | 3 | 0 | 3 |
| ZDHHC2 | NCOA2 | 0.674085 | 3 | 0 | 3 |
| ZDHHC2 | NUDT16 | 0.660549 | 4 | 0 | 3 |
| ZDHHC2 | MANSC1 | 0.660385 | 5 | 0 | 5 |
| ZDHHC2 | SLC46A2 | 0.657266 | 3 | 0 | 3 |
| ZDHHC2 | MAP2K6 | 0.655568 | 5 | 0 | 4 |
| ZDHHC2 | SEMA4D | 0.652657 | 3 | 0 | 3 |
| ZDHHC2 | CHD9 | 0.649808 | 3 | 0 | 3 |
| ZDHHC2 | APIP | 0.647488 | 4 | 0 | 3 |
| ZDHHC2 | MEGF9 | 0.64452 | 4 | 0 | 3 |
| ZDHHC2 | ORC4 | 0.642724 | 4 | 0 | 4 |
| ZDHHC2 | DYNLL2 | 0.641907 | 3 | 0 | 3 |
For details and further investigation, click here
