| Full name: zinc finger protein 516 | Alias Symbol: HsT287|KIAA0222 | ||
| Type: protein-coding gene | Cytoband: 18q23 | ||
| Entrez ID: 9658 | HGNC ID: HGNC:28990 | Ensembl Gene: ENSG00000101493 | OMIM ID: 615114 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF516:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF516 | 9658 | 203604_at | -0.1743 | 0.7027 | |
| GSE20347 | ZNF516 | 9658 | 203604_at | -0.2966 | 0.0066 | |
| GSE23400 | ZNF516 | 9658 | 203604_at | -0.0802 | 0.0601 | |
| GSE26886 | ZNF516 | 9658 | 203604_at | -0.4531 | 0.0331 | |
| GSE29001 | ZNF516 | 9658 | 203604_at | -0.3481 | 0.2364 | |
| GSE38129 | ZNF516 | 9658 | 203604_at | -0.3011 | 0.0458 | |
| GSE45670 | ZNF516 | 9658 | 203604_at | -0.3946 | 0.0146 | |
| GSE53622 | ZNF516 | 9658 | 59101 | -0.3052 | 0.0013 | |
| GSE53624 | ZNF516 | 9658 | 13117 | -0.0018 | 0.9856 | |
| GSE63941 | ZNF516 | 9658 | 203604_at | -1.7307 | 0.0008 | |
| GSE77861 | ZNF516 | 9658 | 203604_at | 0.0071 | 0.9687 | |
| GSE97050 | ZNF516 | 9658 | A_33_P3225690 | -0.4192 | 0.3156 | |
| SRP007169 | ZNF516 | 9658 | RNAseq | -0.8635 | 0.0137 | |
| SRP008496 | ZNF516 | 9658 | RNAseq | -0.7547 | 0.0055 | |
| SRP064894 | ZNF516 | 9658 | RNAseq | -0.4093 | 0.0356 | |
| SRP133303 | ZNF516 | 9658 | RNAseq | -0.4040 | 0.0005 | |
| SRP159526 | ZNF516 | 9658 | RNAseq | -0.2750 | 0.1932 | |
| SRP193095 | ZNF516 | 9658 | RNAseq | -0.0825 | 0.4734 | |
| SRP219564 | ZNF516 | 9658 | RNAseq | -0.4620 | 0.1991 | |
| TCGA | ZNF516 | 9658 | RNAseq | -0.1392 | 0.0850 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZNF516 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF516:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF516 | 9658 | 0 | 11 | 19 | |
| GSE20123 | ZNF516 | 9658 | 0 | 11 | 19 | |
| GSE43470 | ZNF516 | 9658 | 0 | 7 | 36 | |
| GSE46452 | ZNF516 | 9658 | 1 | 26 | 32 | |
| GSE47630 | ZNF516 | 9658 | 5 | 22 | 13 | |
| GSE54993 | ZNF516 | 9658 | 9 | 0 | 61 | |
| GSE54994 | ZNF516 | 9658 | 1 | 18 | 34 | |
| GSE60625 | ZNF516 | 9658 | 0 | 4 | 7 | |
| GSE74703 | ZNF516 | 9658 | 0 | 6 | 30 | |
| GSE74704 | ZNF516 | 9658 | 0 | 9 | 11 | |
| TCGA | ZNF516 | 9658 | 6 | 48 | 42 |
Total number of gains: 22; Total number of losses: 162; Total Number of normals: 304.
Somatic mutations of ZNF516:
Generating mutation plots.
Highly correlated genes for ZNF516:
Showing top 20/301 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF516 | SYNC | 0.731288 | 3 | 0 | 3 |
| ZNF516 | HDHD2 | 0.719464 | 3 | 0 | 3 |
| ZNF516 | BDNF | 0.713743 | 3 | 0 | 3 |
| ZNF516 | GGNBP2 | 0.708122 | 3 | 0 | 3 |
| ZNF516 | KLC1 | 0.705074 | 4 | 0 | 4 |
| ZNF516 | ZDHHC2 | 0.700511 | 4 | 0 | 4 |
| ZNF516 | CAMK1 | 0.691713 | 3 | 0 | 3 |
| ZNF516 | ANGPT1 | 0.676585 | 4 | 0 | 3 |
| ZNF516 | PRMT2 | 0.676053 | 3 | 0 | 3 |
| ZNF516 | TXNL4A | 0.67171 | 5 | 0 | 5 |
| ZNF516 | SMO | 0.667324 | 4 | 0 | 3 |
| ZNF516 | PIGB | 0.664502 | 3 | 0 | 3 |
| ZNF516 | CAPRIN1 | 0.660757 | 3 | 0 | 3 |
| ZNF516 | SLC30A4 | 0.65967 | 3 | 0 | 3 |
| ZNF516 | USP9Y | 0.658218 | 3 | 0 | 3 |
| ZNF516 | CC2D2A | 0.657676 | 4 | 0 | 3 |
| ZNF516 | PARD3B | 0.657608 | 4 | 0 | 3 |
| ZNF516 | FGF7 | 0.653195 | 5 | 0 | 4 |
| ZNF516 | TMEM129 | 0.652213 | 3 | 0 | 3 |
| ZNF516 | TMEM98 | 0.650871 | 4 | 0 | 3 |
For details and further investigation, click here
