| Full name: SURF1 cytochrome c oxidase assembly factor | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q34.2 | ||
| Entrez ID: 6834 | HGNC ID: HGNC:11474 | Ensembl Gene: ENSG00000148290 | OMIM ID: 185620 |
| Drug and gene relationship at DGIdb | |||
Expression of SURF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SURF1 | 6834 | 204295_at | -0.2636 | 0.6275 | |
| GSE20347 | SURF1 | 6834 | 204295_at | -0.3094 | 0.0221 | |
| GSE23400 | SURF1 | 6834 | 204295_at | 0.0956 | 0.1587 | |
| GSE26886 | SURF1 | 6834 | 204295_at | 0.2524 | 0.3371 | |
| GSE29001 | SURF1 | 6834 | 204295_at | 0.0970 | 0.7587 | |
| GSE38129 | SURF1 | 6834 | 204295_at | -0.2978 | 0.0296 | |
| GSE45670 | SURF1 | 6834 | 204295_at | 0.0427 | 0.8041 | |
| GSE53622 | SURF1 | 6834 | 86571 | -0.3057 | 0.0001 | |
| GSE53624 | SURF1 | 6834 | 86571 | 0.0810 | 0.3652 | |
| GSE63941 | SURF1 | 6834 | 204295_at | 0.4173 | 0.4898 | |
| GSE77861 | SURF1 | 6834 | 204295_at | 0.0979 | 0.7867 | |
| GSE97050 | SURF1 | 6834 | A_33_P3292560 | -0.0585 | 0.7798 | |
| SRP007169 | SURF1 | 6834 | RNAseq | -0.4818 | 0.1746 | |
| SRP008496 | SURF1 | 6834 | RNAseq | -0.5748 | 0.0227 | |
| SRP064894 | SURF1 | 6834 | RNAseq | 0.2594 | 0.4341 | |
| SRP133303 | SURF1 | 6834 | RNAseq | -0.1639 | 0.2988 | |
| SRP159526 | SURF1 | 6834 | RNAseq | 0.0957 | 0.6110 | |
| SRP193095 | SURF1 | 6834 | RNAseq | -0.2420 | 0.0497 | |
| SRP219564 | SURF1 | 6834 | RNAseq | -0.1841 | 0.6326 | |
| TCGA | SURF1 | 6834 | RNAseq | -0.2660 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SURF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SURF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SURF1 | 6834 | 5 | 7 | 18 | |
| GSE20123 | SURF1 | 6834 | 5 | 7 | 18 | |
| GSE43470 | SURF1 | 6834 | 4 | 7 | 32 | |
| GSE46452 | SURF1 | 6834 | 6 | 13 | 40 | |
| GSE47630 | SURF1 | 6834 | 4 | 15 | 21 | |
| GSE54993 | SURF1 | 6834 | 3 | 3 | 64 | |
| GSE54994 | SURF1 | 6834 | 12 | 9 | 32 | |
| GSE60625 | SURF1 | 6834 | 0 | 0 | 11 | |
| GSE74703 | SURF1 | 6834 | 4 | 5 | 27 | |
| GSE74704 | SURF1 | 6834 | 3 | 5 | 12 | |
| TCGA | SURF1 | 6834 | 28 | 26 | 42 |
Total number of gains: 74; Total number of losses: 97; Total Number of normals: 317.
Somatic mutations of SURF1:
Generating mutation plots.
Highly correlated genes for SURF1:
Showing top 20/231 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SURF1 | CENPBD1 | 0.775793 | 3 | 0 | 3 |
| SURF1 | TMEM185A | 0.762502 | 3 | 0 | 3 |
| SURF1 | VPS28 | 0.73171 | 3 | 0 | 3 |
| SURF1 | ZNF740 | 0.718919 | 3 | 0 | 3 |
| SURF1 | CDC26 | 0.711229 | 4 | 0 | 3 |
| SURF1 | RWDD2A | 0.706995 | 4 | 0 | 4 |
| SURF1 | CAPZA2 | 0.706019 | 4 | 0 | 4 |
| SURF1 | FGF7 | 0.703594 | 3 | 0 | 3 |
| SURF1 | POLR3C | 0.697637 | 3 | 0 | 3 |
| SURF1 | CCL28 | 0.694612 | 3 | 0 | 3 |
| SURF1 | EIF2AK3 | 0.689674 | 3 | 0 | 3 |
| SURF1 | RRAGB | 0.687899 | 5 | 0 | 4 |
| SURF1 | KLHL5 | 0.685369 | 3 | 0 | 3 |
| SURF1 | SLC24A1 | 0.676515 | 4 | 0 | 3 |
| SURF1 | LRFN5 | 0.676015 | 3 | 0 | 3 |
| SURF1 | RNASE4 | 0.675802 | 3 | 0 | 3 |
| SURF1 | FBLN1 | 0.674406 | 3 | 0 | 3 |
| SURF1 | CPA6 | 0.672975 | 3 | 0 | 3 |
| SURF1 | CNOT7 | 0.66745 | 3 | 0 | 3 |
| SURF1 | PARP16 | 0.666491 | 5 | 0 | 4 |
For details and further investigation, click here
