| Full name: zinc finger protein 488 | Alias Symbol: FLJ32104 | ||
| Type: protein-coding gene | Cytoband: 10q11.22 | ||
| Entrez ID: 118738 | HGNC ID: HGNC:23535 | Ensembl Gene: ENSG00000265763 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF488:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF488 | 118738 | 229901_at | 0.6257 | 0.1835 | |
| GSE26886 | ZNF488 | 118738 | 229901_at | 0.2384 | 0.1994 | |
| GSE45670 | ZNF488 | 118738 | 229901_at | 0.2145 | 0.1053 | |
| GSE53622 | ZNF488 | 118738 | 62630 | 0.6959 | 0.0000 | |
| GSE53624 | ZNF488 | 118738 | 62630 | 0.6422 | 0.0000 | |
| GSE63941 | ZNF488 | 118738 | 229901_at | 2.0051 | 0.0446 | |
| GSE77861 | ZNF488 | 118738 | 229901_at | 0.2016 | 0.3265 | |
| GSE97050 | ZNF488 | 118738 | A_23_P23966 | 0.3284 | 0.3796 | |
| SRP133303 | ZNF488 | 118738 | RNAseq | 0.9154 | 0.0141 | |
| SRP159526 | ZNF488 | 118738 | RNAseq | 0.3539 | 0.5156 | |
| SRP219564 | ZNF488 | 118738 | RNAseq | 1.3320 | 0.1466 | |
| TCGA | ZNF488 | 118738 | RNAseq | 0.8759 | 0.0004 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZNF488 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF488:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF488 | 118738 | 2 | 5 | 23 | |
| GSE20123 | ZNF488 | 118738 | 2 | 5 | 23 | |
| GSE43470 | ZNF488 | 118738 | 1 | 6 | 36 | |
| GSE46452 | ZNF488 | 118738 | 0 | 13 | 46 | |
| GSE47630 | ZNF488 | 118738 | 4 | 13 | 23 | |
| GSE54993 | ZNF488 | 118738 | 9 | 0 | 61 | |
| GSE54994 | ZNF488 | 118738 | 2 | 10 | 41 | |
| GSE60625 | ZNF488 | 118738 | 0 | 0 | 11 | |
| GSE74703 | ZNF488 | 118738 | 1 | 3 | 32 | |
| GSE74704 | ZNF488 | 118738 | 1 | 4 | 15 | |
| TCGA | ZNF488 | 118738 | 16 | 18 | 62 |
Total number of gains: 38; Total number of losses: 77; Total Number of normals: 373.
Somatic mutations of ZNF488:
Generating mutation plots.
Highly correlated genes for ZNF488:
Showing top 20/296 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF488 | CCDC88B | 0.745968 | 3 | 0 | 3 |
| ZNF488 | PKMYT1 | 0.707201 | 4 | 0 | 4 |
| ZNF488 | CHRNA5 | 0.693571 | 4 | 0 | 4 |
| ZNF488 | ZNHIT2 | 0.682796 | 4 | 0 | 3 |
| ZNF488 | PLTP | 0.677437 | 3 | 0 | 3 |
| ZNF488 | HSD17B1 | 0.66709 | 3 | 0 | 3 |
| ZNF488 | LTBR | 0.664037 | 3 | 0 | 3 |
| ZNF488 | ORAI1 | 0.66133 | 4 | 0 | 4 |
| ZNF488 | FAM181B | 0.651169 | 3 | 0 | 3 |
| ZNF488 | TK1 | 0.650141 | 6 | 0 | 5 |
| ZNF488 | TOMM40 | 0.64966 | 3 | 0 | 3 |
| ZNF488 | HYPK | 0.648948 | 3 | 0 | 3 |
| ZNF488 | MEI1 | 0.640914 | 3 | 0 | 3 |
| ZNF488 | EXO1 | 0.639754 | 7 | 0 | 6 |
| ZNF488 | TMEM223 | 0.637899 | 4 | 0 | 3 |
| ZNF488 | KIF18B | 0.637588 | 5 | 0 | 4 |
| ZNF488 | CD276 | 0.635012 | 4 | 0 | 4 |
| ZNF488 | RALY | 0.631618 | 4 | 0 | 4 |
| ZNF488 | WAS | 0.625848 | 3 | 0 | 3 |
| ZNF488 | SLC7A5 | 0.622504 | 5 | 0 | 3 |
For details and further investigation, click here
