ABHD17B

 

Full name: abhydrolase domain containing 17B Alias Symbol: CGI-67
Type: protein-coding gene Cytoband: 9q21.13
Entrez ID: 51104 HGNC ID: HGNC:24278 Ensembl Gene: ENSG00000107362 OMIM ID: 617943
Drug and gene relationship at DGIdb

 

Expression of ABHD17B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ABHD17B 51104 227551_at -0.2378 0.7782
GSE20347 ABHD17B 51104 220285_at -0.2315 0.0046
GSE23400 ABHD17B 51104 220285_at -0.0577 0.3922
GSE26886 ABHD17B 51104 227551_at -0.6511 0.0020
GSE29001 ABHD17B 51104 220285_at -0.4270 0.0171
GSE38129 ABHD17B 51104 220285_at -0.1106 0.3949
GSE45670 ABHD17B 51104 227551_at -0.1855 0.3004
GSE53622 ABHD17B 51104 10862 -0.6905 0.0000
GSE53624 ABHD17B 51104 10862 -0.5505 0.0000
GSE63941 ABHD17B 51104 227551_at -0.1183 0.7997
GSE77861 ABHD17B 51104 227551_at 0.0266 0.9608
SRP007169 ABHD17B 51104 RNAseq -1.0852 0.0536
SRP008496 ABHD17B 51104 RNAseq -1.0906 0.0009
SRP064894 ABHD17B 51104 RNAseq -0.7902 0.0016
SRP133303 ABHD17B 51104 RNAseq -0.4733 0.0236
SRP159526 ABHD17B 51104 RNAseq -0.5233 0.0725
SRP193095 ABHD17B 51104 RNAseq -0.9562 0.0000
SRP219564 ABHD17B 51104 RNAseq -0.6494 0.1638

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by ABHD17B expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  


Copy number change of ABHD17B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ABHD17B 51104 6 11 13
GSE20123 ABHD17B 51104 6 11 13
GSE43470 ABHD17B 51104 6 5 32
GSE46452 ABHD17B 51104 6 14 39
GSE47630 ABHD17B 51104 1 18 21
GSE54993 ABHD17B 51104 4 1 65
GSE54994 ABHD17B 51104 4 13 36
GSE60625 ABHD17B 51104 0 0 11
GSE74703 ABHD17B 51104 5 4 27
GSE74704 ABHD17B 51104 3 8 9
TCGA ABHD17B 51104 19 27 50

Total number of gains: 60; Total number of losses: 112; Total Number of normals: 316.  


 

Somatic mutations of ABHD17B:

 

Generating mutation plots.

 

Highly correlated genes for ABHD17B:

 

Showing top 20/702 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ABHD17BTPRN0.693469303
ABHD17BNHSL10.692709403
ABHD17BGNL30.683766303
ABHD17BMACC10.67705403
ABHD17BRHBDL20.674069404
ABHD17BSPTLC10.67211807
ABHD17BGSKIP0.672097404
ABHD17BZNF8230.665302504
ABHD17BC9orf850.664446707
ABHD17BEP300-AS10.661555303
ABHD17BABHD120.656911303
ABHD17BFRMD60.648455403
ABHD17BGPR1570.643322403
ABHD17BZNF850.64139303
ABHD17BSTK240.638556706
ABHD17BBTBD100.63765504
ABHD17BPROM20.636818404
ABHD17BAP1M20.635697504
ABHD17BTLE40.634405403
ABHD17BTWF10.634226707

For details and further investigation, click here