| Full name: AHNAK nucleoprotein 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q32.33 | ||
| Entrez ID: 113146 | HGNC ID: HGNC:20125 | Ensembl Gene: ENSG00000185567 | OMIM ID: 608570 |
| Drug and gene relationship at DGIdb | |||
Expression of AHNAK2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AHNAK2 | 113146 | 212992_at | -1.1205 | 0.3093 | |
| GSE20347 | AHNAK2 | 113146 | 212992_at | -1.1654 | 0.0023 | |
| GSE23400 | AHNAK2 | 113146 | 212992_at | -0.5094 | 0.0017 | |
| GSE26886 | AHNAK2 | 113146 | 212992_at | 0.2088 | 0.5394 | |
| GSE29001 | AHNAK2 | 113146 | 212992_at | -0.8645 | 0.2198 | |
| GSE38129 | AHNAK2 | 113146 | 212992_at | -1.0057 | 0.0052 | |
| GSE45670 | AHNAK2 | 113146 | 212992_at | -0.1401 | 0.5953 | |
| GSE53622 | AHNAK2 | 113146 | 150381 | -0.6338 | 0.0026 | |
| GSE53624 | AHNAK2 | 113146 | 150381 | -0.5979 | 0.0000 | |
| GSE63941 | AHNAK2 | 113146 | 212992_at | -1.0127 | 0.3570 | |
| GSE77861 | AHNAK2 | 113146 | 212992_at | 0.0388 | 0.9608 | |
| GSE97050 | AHNAK2 | 113146 | A_33_P3222380 | -0.2922 | 0.2151 | |
| SRP007169 | AHNAK2 | 113146 | RNAseq | 0.4307 | 0.3147 | |
| SRP008496 | AHNAK2 | 113146 | RNAseq | 0.2221 | 0.4388 | |
| SRP064894 | AHNAK2 | 113146 | RNAseq | -0.4151 | 0.1279 | |
| SRP133303 | AHNAK2 | 113146 | RNAseq | -0.0827 | 0.7755 | |
| SRP159526 | AHNAK2 | 113146 | RNAseq | -0.8313 | 0.2449 | |
| SRP193095 | AHNAK2 | 113146 | RNAseq | -0.0835 | 0.8277 | |
| SRP219564 | AHNAK2 | 113146 | RNAseq | -0.0104 | 0.9853 | |
| TCGA | AHNAK2 | 113146 | RNAseq | 0.2288 | 0.0942 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by AHNAK2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AHNAK2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AHNAK2 | 113146 | 11 | 3 | 16 | |
| GSE20123 | AHNAK2 | 113146 | 10 | 2 | 18 | |
| GSE43470 | AHNAK2 | 113146 | 6 | 4 | 33 | |
| GSE46452 | AHNAK2 | 113146 | 18 | 4 | 37 | |
| GSE47630 | AHNAK2 | 113146 | 10 | 8 | 22 | |
| GSE54993 | AHNAK2 | 113146 | 4 | 10 | 56 | |
| GSE54994 | AHNAK2 | 113146 | 21 | 4 | 28 | |
| GSE60625 | AHNAK2 | 113146 | 0 | 2 | 9 | |
| GSE74703 | AHNAK2 | 113146 | 5 | 3 | 28 | |
| GSE74704 | AHNAK2 | 113146 | 5 | 2 | 13 | |
| TCGA | AHNAK2 | 113146 | 32 | 18 | 46 |
Total number of gains: 122; Total number of losses: 60; Total Number of normals: 306.
Somatic mutations of AHNAK2:
Generating mutation plots.
Highly correlated genes for AHNAK2:
Showing top 20/297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AHNAK2 | TTC37 | 0.716866 | 3 | 0 | 3 |
| AHNAK2 | S100A10 | 0.667591 | 11 | 0 | 10 |
| AHNAK2 | HEXIM1 | 0.66536 | 3 | 0 | 3 |
| AHNAK2 | AHNAK | 0.6611 | 11 | 0 | 10 |
| AHNAK2 | BAG5 | 0.659369 | 6 | 0 | 6 |
| AHNAK2 | ESYT2 | 0.650392 | 3 | 0 | 3 |
| AHNAK2 | INVS | 0.642949 | 3 | 0 | 3 |
| AHNAK2 | HIGD1A | 0.638633 | 6 | 0 | 4 |
| AHNAK2 | PHPT1 | 0.638543 | 3 | 0 | 3 |
| AHNAK2 | LGALS3 | 0.638269 | 9 | 0 | 8 |
| AHNAK2 | CCDC80 | 0.633899 | 3 | 0 | 3 |
| AHNAK2 | CCNYL1 | 0.629153 | 3 | 0 | 3 |
| AHNAK2 | EIF4E2 | 0.624904 | 3 | 0 | 3 |
| AHNAK2 | ATG10 | 0.621352 | 3 | 0 | 3 |
| AHNAK2 | MYADM | 0.620635 | 3 | 0 | 3 |
| AHNAK2 | RAB13 | 0.615891 | 3 | 0 | 3 |
| AHNAK2 | SPTBN2 | 0.615232 | 3 | 0 | 3 |
| AHNAK2 | TRAF3IP2 | 0.609592 | 4 | 0 | 3 |
| AHNAK2 | TTC8 | 0.609168 | 4 | 0 | 3 |
| AHNAK2 | ADARB1 | 0.609089 | 3 | 0 | 3 |
For details and further investigation, click here
