| Full name: adenylate kinase 6 | Alias Symbol: CINAP | ||
| Type: protein-coding gene | Cytoband: 5q13.2 | ||
| Entrez ID: 102157402 | HGNC ID: HGNC:49151 | Ensembl Gene: ENSG00000085231 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of AK6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AK6 | 102157402 | 203893_at | -0.0074 | 0.9892 | |
| GSE20347 | AK6 | 102157402 | 203893_at | 0.0936 | 0.4371 | |
| GSE23400 | AK6 | 102157402 | 203893_at | 0.2835 | 0.0000 | |
| GSE26886 | AK6 | 102157402 | 203893_at | 0.3491 | 0.2564 | |
| GSE29001 | AK6 | 102157402 | 203893_at | 0.1858 | 0.6487 | |
| GSE38129 | AK6 | 102157402 | 203893_at | 0.1091 | 0.2604 | |
| GSE45670 | AK6 | 102157402 | 203893_at | -0.2331 | 0.1491 | |
| GSE53622 | AK6 | 102157402 | 148757 | -0.0868 | 0.1161 | |
| GSE53624 | AK6 | 102157402 | 148757 | -0.0612 | 0.5260 | |
| GSE63941 | AK6 | 102157402 | 203893_at | -0.3464 | 0.4264 | |
| GSE77861 | AK6 | 102157402 | 203893_at | -0.1843 | 0.4278 | |
| SRP007169 | AK6 | 102157402 | RNAseq | 1.0106 | 0.1331 | |
| SRP064894 | AK6 | 102157402 | RNAseq | -0.1900 | 0.1864 | |
| SRP133303 | AK6 | 102157402 | RNAseq | 0.0577 | 0.7051 | |
| SRP159526 | AK6 | 102157402 | RNAseq | -0.0974 | 0.7806 | |
| SRP193095 | AK6 | 102157402 | RNAseq | -0.3393 | 0.0043 | |
| SRP219564 | AK6 | 102157402 | RNAseq | -0.4738 | 0.0947 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AK6 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of AK6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AK6 | 102157402 | 1 | 13 | 16 | |
| GSE20123 | AK6 | 102157402 | 1 | 13 | 16 | |
| GSE43470 | AK6 | 102157402 | 1 | 12 | 30 | |
| GSE46452 | AK6 | 102157402 | 0 | 28 | 31 | |
| GSE47630 | AK6 | 102157402 | 2 | 17 | 21 | |
| GSE54993 | AK6 | 102157402 | 8 | 1 | 61 | |
| GSE54994 | AK6 | 102157402 | 1 | 21 | 31 | |
| GSE60625 | AK6 | 102157402 | 0 | 0 | 11 | |
| GSE74703 | AK6 | 102157402 | 1 | 9 | 26 | |
| GSE74704 | AK6 | 102157402 | 1 | 6 | 13 |
Total number of gains: 16; Total number of losses: 120; Total Number of normals: 256.
Somatic mutations of AK6:
Generating mutation plots.
Highly correlated genes for AK6:
Showing top 20/170 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AK6 | GFM2 | 0.692039 | 4 | 0 | 3 |
| AK6 | MRPL42 | 0.654972 | 3 | 0 | 3 |
| AK6 | MRPS18B | 0.647933 | 4 | 0 | 3 |
| AK6 | OLA1 | 0.641252 | 3 | 0 | 3 |
| AK6 | ATG12 | 0.625452 | 5 | 0 | 4 |
| AK6 | UBR3 | 0.61906 | 4 | 0 | 3 |
| AK6 | NDUFAF2 | 0.617135 | 7 | 0 | 6 |
| AK6 | MSH3 | 0.60923 | 4 | 0 | 4 |
| AK6 | SRP19 | 0.602508 | 7 | 0 | 5 |
| AK6 | RIOK2 | 0.600464 | 9 | 0 | 7 |
| AK6 | MRPL13 | 0.598449 | 4 | 0 | 3 |
| AK6 | PAFAH1B2 | 0.597255 | 3 | 0 | 3 |
| AK6 | AIMP1 | 0.596305 | 4 | 0 | 3 |
| AK6 | CRYZL1 | 0.59447 | 4 | 0 | 3 |
| AK6 | ACTR6 | 0.593352 | 6 | 0 | 4 |
| AK6 | KIF3A | 0.592554 | 4 | 0 | 3 |
| AK6 | G3BP1 | 0.592195 | 4 | 0 | 3 |
| AK6 | MTX3 | 0.591412 | 5 | 0 | 5 |
| AK6 | HTATSF1 | 0.591134 | 5 | 0 | 5 |
| AK6 | SLC30A5 | 0.58887 | 10 | 0 | 8 |
For details and further investigation, click here
