| Full name: sulfatase 1 | Alias Symbol: KIAA1077|SULF-1|hSulf-1 | ||
| Type: protein-coding gene | Cytoband: 8q13.2-q13.3 | ||
| Entrez ID: 23213 | HGNC ID: HGNC:20391 | Ensembl Gene: ENSG00000137573 | OMIM ID: 610012 |
| Drug and gene relationship at DGIdb | |||
Expression of SULF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SULF1 | 23213 | 212354_at | 1.0523 | 0.3436 | |
| GSE20347 | SULF1 | 23213 | 212354_at | 1.8490 | 0.0000 | |
| GSE23400 | SULF1 | 23213 | 212354_at | 1.7927 | 0.0000 | |
| GSE26886 | SULF1 | 23213 | 212354_at | 2.6322 | 0.0000 | |
| GSE29001 | SULF1 | 23213 | 212354_at | 1.4737 | 0.0041 | |
| GSE38129 | SULF1 | 23213 | 212354_at | 1.8969 | 0.0000 | |
| GSE45670 | SULF1 | 23213 | 212354_at | -0.2891 | 0.6564 | |
| GSE53622 | SULF1 | 23213 | 49025 | 2.3123 | 0.0000 | |
| GSE53624 | SULF1 | 23213 | 49025 | 2.4949 | 0.0000 | |
| GSE63941 | SULF1 | 23213 | 212354_at | -4.5644 | 0.0084 | |
| GSE77861 | SULF1 | 23213 | 212354_at | 1.2013 | 0.0234 | |
| GSE97050 | SULF1 | 23213 | A_23_P43164 | 2.3111 | 0.0465 | |
| SRP007169 | SULF1 | 23213 | RNAseq | 5.6707 | 0.0000 | |
| SRP008496 | SULF1 | 23213 | RNAseq | 6.4426 | 0.0000 | |
| SRP064894 | SULF1 | 23213 | RNAseq | 2.5853 | 0.0000 | |
| SRP133303 | SULF1 | 23213 | RNAseq | 2.8697 | 0.0000 | |
| SRP159526 | SULF1 | 23213 | RNAseq | 1.8622 | 0.0000 | |
| SRP193095 | SULF1 | 23213 | RNAseq | 3.2429 | 0.0000 | |
| SRP219564 | SULF1 | 23213 | RNAseq | 1.4485 | 0.0578 | |
| TCGA | SULF1 | 23213 | RNAseq | 0.4580 | 0.0005 |
Upregulated datasets: 15; Downregulated datasets: 1.
Survival by SULF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SULF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SULF1 | 23213 | 15 | 1 | 14 | |
| GSE20123 | SULF1 | 23213 | 16 | 1 | 13 | |
| GSE43470 | SULF1 | 23213 | 18 | 1 | 24 | |
| GSE46452 | SULF1 | 23213 | 20 | 2 | 37 | |
| GSE47630 | SULF1 | 23213 | 23 | 1 | 16 | |
| GSE54993 | SULF1 | 23213 | 0 | 19 | 51 | |
| GSE54994 | SULF1 | 23213 | 30 | 0 | 23 | |
| GSE60625 | SULF1 | 23213 | 0 | 4 | 7 | |
| GSE74703 | SULF1 | 23213 | 15 | 1 | 20 | |
| GSE74704 | SULF1 | 23213 | 11 | 0 | 9 | |
| TCGA | SULF1 | 23213 | 50 | 4 | 42 |
Total number of gains: 198; Total number of losses: 34; Total Number of normals: 256.
Somatic mutations of SULF1:
Generating mutation plots.
Highly correlated genes for SULF1:
Showing top 20/1144 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SULF1 | VCAN | 0.873321 | 13 | 0 | 13 |
| SULF1 | COL6A3 | 0.835127 | 13 | 0 | 13 |
| SULF1 | SPARC | 0.830867 | 13 | 0 | 13 |
| SULF1 | POSTN | 0.830334 | 13 | 0 | 13 |
| SULF1 | CDH11 | 0.82941 | 13 | 0 | 13 |
| SULF1 | COL3A1 | 0.822278 | 13 | 0 | 13 |
| SULF1 | FNDC1 | 0.811528 | 8 | 0 | 8 |
| SULF1 | CTSK | 0.807882 | 13 | 0 | 13 |
| SULF1 | COL1A2 | 0.803864 | 13 | 0 | 13 |
| SULF1 | FN1 | 0.802264 | 12 | 0 | 12 |
| SULF1 | FAP | 0.798959 | 11 | 0 | 11 |
| SULF1 | COL5A2 | 0.790504 | 13 | 0 | 12 |
| SULF1 | COL10A1 | 0.788894 | 11 | 0 | 11 |
| SULF1 | NOX4 | 0.788037 | 12 | 0 | 12 |
| SULF1 | THY1 | 0.786299 | 13 | 0 | 12 |
| SULF1 | COL1A1 | 0.783613 | 12 | 0 | 12 |
| SULF1 | OLFML2B | 0.783414 | 12 | 0 | 12 |
| SULF1 | CALU | 0.781879 | 12 | 0 | 12 |
| SULF1 | LUM | 0.780746 | 13 | 0 | 13 |
| SULF1 | ISLR | 0.772353 | 12 | 0 | 11 |
For details and further investigation, click here
