| Full name: anaphase promoting complex subunit 15 | Alias Symbol: HSPC020|DKFZP564M082|APC15 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 25906 | HGNC ID: HGNC:24531 | Ensembl Gene: ENSG00000110200 | OMIM ID: 614717 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ANAPC15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANAPC15 | 25906 | 204218_at | 0.4694 | 0.3986 | |
| GSE20347 | ANAPC15 | 25906 | 204218_at | -0.1387 | 0.4966 | |
| GSE23400 | ANAPC15 | 25906 | 204218_at | 0.0294 | 0.7335 | |
| GSE26886 | ANAPC15 | 25906 | 204218_at | 0.2856 | 0.3557 | |
| GSE29001 | ANAPC15 | 25906 | 204218_at | -0.2524 | 0.2780 | |
| GSE38129 | ANAPC15 | 25906 | 204218_at | -0.1474 | 0.3595 | |
| GSE45670 | ANAPC15 | 25906 | 204218_at | 0.1173 | 0.5988 | |
| GSE53622 | ANAPC15 | 25906 | 105912 | 0.0640 | 0.5187 | |
| GSE53624 | ANAPC15 | 25906 | 105912 | 0.2271 | 0.0034 | |
| GSE63941 | ANAPC15 | 25906 | 204218_at | 0.9361 | 0.1100 | |
| GSE77861 | ANAPC15 | 25906 | 204218_at | -0.2432 | 0.3573 | |
| SRP007169 | ANAPC15 | 25906 | RNAseq | -0.3952 | 0.3319 | |
| SRP008496 | ANAPC15 | 25906 | RNAseq | -0.0290 | 0.9377 | |
| SRP064894 | ANAPC15 | 25906 | RNAseq | 0.3446 | 0.3260 | |
| SRP133303 | ANAPC15 | 25906 | RNAseq | 0.8495 | 0.0033 | |
| SRP159526 | ANAPC15 | 25906 | RNAseq | -0.4869 | 0.1708 | |
| SRP193095 | ANAPC15 | 25906 | RNAseq | 0.0093 | 0.9557 | |
| SRP219564 | ANAPC15 | 25906 | RNAseq | -0.1793 | 0.6736 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANAPC15 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ANAPC15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANAPC15 | 25906 | 10 | 7 | 13 | |
| GSE20123 | ANAPC15 | 25906 | 10 | 7 | 13 | |
| GSE43470 | ANAPC15 | 25906 | 9 | 4 | 30 | |
| GSE46452 | ANAPC15 | 25906 | 12 | 17 | 30 | |
| GSE47630 | ANAPC15 | 25906 | 10 | 10 | 20 | |
| GSE54993 | ANAPC15 | 25906 | 7 | 3 | 60 | |
| GSE54994 | ANAPC15 | 25906 | 14 | 11 | 28 | |
| GSE60625 | ANAPC15 | 25906 | 0 | 7 | 4 | |
| GSE74703 | ANAPC15 | 25906 | 7 | 3 | 26 | |
| GSE74704 | ANAPC15 | 25906 | 7 | 4 | 9 | |
| TCGA | ANAPC15 | 25906 | 36 | 20 | 40 |
Total number of gains: 122; Total number of losses: 93; Total Number of normals: 273.
Somatic mutations of ANAPC15:
Generating mutation plots.
Highly correlated genes for ANAPC15:
Showing top 20/35 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANAPC15 | LAMTOR1 | 0.708356 | 7 | 0 | 7 |
| ANAPC15 | ASF1B | 0.706242 | 3 | 0 | 3 |
| ANAPC15 | LRTOMT | 0.642426 | 7 | 0 | 5 |
| ANAPC15 | RARG | 0.641776 | 3 | 0 | 3 |
| ANAPC15 | XKR8 | 0.640962 | 3 | 0 | 3 |
| ANAPC15 | ARAF | 0.630565 | 4 | 0 | 3 |
| ANAPC15 | FPGS | 0.630272 | 4 | 0 | 3 |
| ANAPC15 | TCTN2 | 0.625598 | 3 | 0 | 3 |
| ANAPC15 | TMPO-AS1 | 0.625322 | 3 | 0 | 3 |
| ANAPC15 | NUMA1 | 0.616008 | 10 | 0 | 10 |
| ANAPC15 | CAPN1 | 0.610072 | 4 | 0 | 3 |
| ANAPC15 | SLC9A3R1 | 0.597064 | 4 | 0 | 4 |
| ANAPC15 | TBC1D10B | 0.596553 | 3 | 0 | 3 |
| ANAPC15 | FSIP2 | 0.577987 | 3 | 0 | 3 |
| ANAPC15 | C9orf16 | 0.57725 | 4 | 0 | 3 |
| ANAPC15 | ESRRA | 0.576428 | 4 | 0 | 3 |
| ANAPC15 | SUV39H1 | 0.568763 | 5 | 0 | 4 |
| ANAPC15 | LRRC61 | 0.566028 | 3 | 0 | 3 |
| ANAPC15 | MOSPD3 | 0.561241 | 4 | 0 | 3 |
| ANAPC15 | SRCAP | 0.560482 | 3 | 0 | 3 |
For details and further investigation, click here
