| Full name: SLC9A3 regulator 1 | Alias Symbol: NHERF|EBP50|NHERF1 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 9368 | HGNC ID: HGNC:11075 | Ensembl Gene: ENSG00000109062 | OMIM ID: 604990 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC9A3R1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC9A3R1 | 9368 | 201349_at | -0.7916 | 0.3086 | |
| GSE20347 | SLC9A3R1 | 9368 | 201349_at | -0.8428 | 0.0002 | |
| GSE23400 | SLC9A3R1 | 9368 | 201349_at | -0.6422 | 0.0000 | |
| GSE26886 | SLC9A3R1 | 9368 | 201349_at | -1.7738 | 0.0000 | |
| GSE29001 | SLC9A3R1 | 9368 | 201349_at | -0.9464 | 0.0393 | |
| GSE38129 | SLC9A3R1 | 9368 | 201349_at | -0.2514 | 0.5231 | |
| GSE45670 | SLC9A3R1 | 9368 | 201349_at | 0.0037 | 0.9899 | |
| GSE53622 | SLC9A3R1 | 9368 | 92132 | -0.9652 | 0.0000 | |
| GSE53624 | SLC9A3R1 | 9368 | 92132 | -1.1928 | 0.0000 | |
| GSE63941 | SLC9A3R1 | 9368 | 201349_at | 3.2744 | 0.0001 | |
| GSE77861 | SLC9A3R1 | 9368 | 201349_at | -0.3324 | 0.5529 | |
| GSE97050 | SLC9A3R1 | 9368 | A_33_P3378835 | 0.2372 | 0.7285 | |
| SRP007169 | SLC9A3R1 | 9368 | RNAseq | -1.4107 | 0.0011 | |
| SRP008496 | SLC9A3R1 | 9368 | RNAseq | -1.5372 | 0.0000 | |
| SRP064894 | SLC9A3R1 | 9368 | RNAseq | -1.5750 | 0.0000 | |
| SRP133303 | SLC9A3R1 | 9368 | RNAseq | -0.9753 | 0.0013 | |
| SRP159526 | SLC9A3R1 | 9368 | RNAseq | -0.3496 | 0.5885 | |
| SRP193095 | SLC9A3R1 | 9368 | RNAseq | -1.0507 | 0.0000 | |
| SRP219564 | SLC9A3R1 | 9368 | RNAseq | -1.2231 | 0.1576 | |
| TCGA | SLC9A3R1 | 9368 | RNAseq | 0.0924 | 0.3368 |
Upregulated datasets: 1; Downregulated datasets: 6.
Survival by SLC9A3R1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC9A3R1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC9A3R1 | 9368 | 3 | 2 | 25 | |
| GSE20123 | SLC9A3R1 | 9368 | 3 | 2 | 25 | |
| GSE43470 | SLC9A3R1 | 9368 | 5 | 3 | 35 | |
| GSE46452 | SLC9A3R1 | 9368 | 33 | 0 | 26 | |
| GSE47630 | SLC9A3R1 | 9368 | 8 | 1 | 31 | |
| GSE54993 | SLC9A3R1 | 9368 | 2 | 5 | 63 | |
| GSE54994 | SLC9A3R1 | 9368 | 10 | 4 | 39 | |
| GSE60625 | SLC9A3R1 | 9368 | 6 | 0 | 5 | |
| GSE74703 | SLC9A3R1 | 9368 | 5 | 1 | 30 | |
| GSE74704 | SLC9A3R1 | 9368 | 3 | 1 | 16 | |
| TCGA | SLC9A3R1 | 9368 | 32 | 10 | 54 |
Total number of gains: 110; Total number of losses: 29; Total Number of normals: 349.
Somatic mutations of SLC9A3R1:
Generating mutation plots.
Highly correlated genes for SLC9A3R1:
Showing top 20/1101 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC9A3R1 | FAM83H | 0.800086 | 3 | 0 | 3 |
| SLC9A3R1 | ARAP2 | 0.76844 | 3 | 0 | 3 |
| SLC9A3R1 | NIPAL1 | 0.758469 | 3 | 0 | 3 |
| SLC9A3R1 | RAPGEFL1 | 0.743422 | 13 | 0 | 12 |
| SLC9A3R1 | CKMT1A | 0.737786 | 3 | 0 | 3 |
| SLC9A3R1 | FAM135A | 0.736116 | 7 | 0 | 7 |
| SLC9A3R1 | SPAG17 | 0.732392 | 4 | 0 | 4 |
| SLC9A3R1 | KLF5 | 0.729053 | 12 | 0 | 12 |
| SLC9A3R1 | DSC2 | 0.728207 | 10 | 0 | 10 |
| SLC9A3R1 | C15orf48 | 0.727604 | 5 | 0 | 5 |
| SLC9A3R1 | SEMA4B | 0.725477 | 5 | 0 | 5 |
| SLC9A3R1 | ADH7 | 0.723313 | 12 | 0 | 10 |
| SLC9A3R1 | S100A16 | 0.721856 | 7 | 0 | 6 |
| SLC9A3R1 | LAD1 | 0.721709 | 12 | 0 | 12 |
| SLC9A3R1 | TRIM29 | 0.71977 | 12 | 0 | 12 |
| SLC9A3R1 | LPAR5 | 0.719256 | 8 | 0 | 7 |
| SLC9A3R1 | TPD52L1 | 0.717597 | 12 | 0 | 10 |
| SLC9A3R1 | EPN3 | 0.716903 | 11 | 0 | 11 |
| SLC9A3R1 | EVPL | 0.715463 | 13 | 0 | 12 |
| SLC9A3R1 | JUP | 0.714216 | 12 | 0 | 11 |
For details and further investigation, click here
