| Full name: leucine rich repeat containing 61 | Alias Symbol: MGC3036|FLJ31392|HSPC295 | ||
| Type: protein-coding gene | Cytoband: 7q36.1 | ||
| Entrez ID: 65999 | HGNC ID: HGNC:21704 | Ensembl Gene: ENSG00000127399 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC61:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC61 | 65999 | 218907_s_at | -0.0117 | 0.9798 | |
| GSE20347 | LRRC61 | 65999 | 218907_s_at | 0.0150 | 0.8760 | |
| GSE23400 | LRRC61 | 65999 | 218907_s_at | 0.0190 | 0.6993 | |
| GSE26886 | LRRC61 | 65999 | 218907_s_at | -0.3083 | 0.0534 | |
| GSE29001 | LRRC61 | 65999 | 218907_s_at | 0.0921 | 0.6182 | |
| GSE38129 | LRRC61 | 65999 | 218907_s_at | 0.0760 | 0.5446 | |
| GSE45670 | LRRC61 | 65999 | 218907_s_at | 0.0947 | 0.3544 | |
| GSE53622 | LRRC61 | 65999 | 12266 | 0.1918 | 0.2223 | |
| GSE53624 | LRRC61 | 65999 | 12266 | 0.1652 | 0.1685 | |
| GSE63941 | LRRC61 | 65999 | 218907_s_at | 0.5009 | 0.0945 | |
| GSE77861 | LRRC61 | 65999 | 218907_s_at | -0.3065 | 0.0481 | |
| GSE97050 | LRRC61 | 65999 | A_33_P3233273 | 0.0569 | 0.8262 | |
| SRP007169 | LRRC61 | 65999 | RNAseq | 0.1473 | 0.7882 | |
| SRP008496 | LRRC61 | 65999 | RNAseq | 0.0289 | 0.9371 | |
| SRP064894 | LRRC61 | 65999 | RNAseq | 0.2185 | 0.3792 | |
| SRP133303 | LRRC61 | 65999 | RNAseq | 0.1102 | 0.5234 | |
| SRP159526 | LRRC61 | 65999 | RNAseq | -0.0629 | 0.8269 | |
| SRP193095 | LRRC61 | 65999 | RNAseq | -0.0588 | 0.6657 | |
| SRP219564 | LRRC61 | 65999 | RNAseq | 0.1772 | 0.6348 | |
| TCGA | LRRC61 | 65999 | RNAseq | 0.0314 | 0.8130 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRRC61 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC61:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC61 | 65999 | 2 | 4 | 24 | |
| GSE20123 | LRRC61 | 65999 | 2 | 4 | 24 | |
| GSE43470 | LRRC61 | 65999 | 2 | 5 | 36 | |
| GSE46452 | LRRC61 | 65999 | 7 | 2 | 50 | |
| GSE47630 | LRRC61 | 65999 | 6 | 8 | 26 | |
| GSE54993 | LRRC61 | 65999 | 3 | 3 | 64 | |
| GSE54994 | LRRC61 | 65999 | 6 | 8 | 39 | |
| GSE60625 | LRRC61 | 65999 | 0 | 0 | 11 | |
| GSE74703 | LRRC61 | 65999 | 2 | 4 | 30 | |
| GSE74704 | LRRC61 | 65999 | 1 | 4 | 15 | |
| TCGA | LRRC61 | 65999 | 25 | 27 | 44 |
Total number of gains: 56; Total number of losses: 69; Total Number of normals: 363.
Somatic mutations of LRRC61:
Generating mutation plots.
Highly correlated genes for LRRC61:
Showing top 20/118 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC61 | MUC20 | 0.730704 | 3 | 0 | 3 |
| LRRC61 | PITX1 | 0.683893 | 3 | 0 | 3 |
| LRRC61 | TRAFD1 | 0.642478 | 3 | 0 | 3 |
| LRRC61 | PNPLA4 | 0.632258 | 3 | 0 | 3 |
| LRRC61 | MST1 | 0.628775 | 3 | 0 | 3 |
| LRRC61 | ZIC1 | 0.627851 | 3 | 0 | 3 |
| LRRC61 | HDAC6 | 0.627466 | 3 | 0 | 3 |
| LRRC61 | SERPINB2 | 0.625356 | 3 | 0 | 3 |
| LRRC61 | PRPF38A | 0.624138 | 3 | 0 | 3 |
| LRRC61 | NOL4 | 0.622678 | 3 | 0 | 3 |
| LRRC61 | HAAO | 0.620763 | 3 | 0 | 3 |
| LRRC61 | CASP5 | 0.62008 | 3 | 0 | 3 |
| LRRC61 | CSK | 0.61445 | 5 | 0 | 3 |
| LRRC61 | CCL23 | 0.604008 | 3 | 0 | 3 |
| LRRC61 | EPO | 0.598733 | 4 | 0 | 4 |
| LRRC61 | SPINT1 | 0.597505 | 4 | 0 | 3 |
| LRRC61 | CCL1 | 0.596067 | 5 | 0 | 4 |
| LRRC61 | ATP6V0C | 0.595734 | 4 | 0 | 4 |
| LRRC61 | BRS3 | 0.584629 | 3 | 0 | 3 |
| LRRC61 | MAZ | 0.583603 | 3 | 0 | 3 |
For details and further investigation, click here
