PSMD2

 

Full name: proteasome 26S subunit, non-ATPase 2 Alias Symbol: S2|P97|TRAP2|MGC14274|Rpn1
Type: protein-coding gene Cytoband: 3q27.1
Entrez ID: 5708 HGNC ID: HGNC:9559 Ensembl Gene: ENSG00000175166 OMIM ID: 606223
Drug and gene relationship at DGIdb

 

Expression of PSMD2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PSMD2 5708 200830_at 0.7110 0.0841
GSE20347 PSMD2 5708 200830_at 0.8980 0.0000
GSE23400 PSMD2 5708 200830_at 0.7625 0.0000
GSE26886 PSMD2 5708 200830_at 0.3830 0.0344
GSE29001 PSMD2 5708 200830_at 0.5124 0.0736
GSE38129 PSMD2 5708 200830_at 1.0085 0.0000
GSE45670 PSMD2 5708 200830_at 0.6830 0.0015
GSE53622 PSMD2 5708 21996 0.9488 0.0000
GSE53624 PSMD2 5708 19315 1.1259 0.0000
GSE63941 PSMD2 5708 200830_at 0.3225 0.5676
GSE77861 PSMD2 5708 200830_at 0.7659 0.0086
GSE97050 PSMD2 5708 A_33_P3373469 0.6802 0.0903
SRP007169 PSMD2 5708 RNAseq 1.0224 0.0406
SRP008496 PSMD2 5708 RNAseq 0.8160 0.0065
SRP064894 PSMD2 5708 RNAseq 0.9382 0.0000
SRP133303 PSMD2 5708 RNAseq 1.1503 0.0000
SRP159526 PSMD2 5708 RNAseq 1.4746 0.0000
SRP193095 PSMD2 5708 RNAseq 0.9955 0.0000
SRP219564 PSMD2 5708 RNAseq 0.4834 0.2810
TCGA PSMD2 5708 RNAseq 0.2641 0.0000

Upregulated datasets: 5; Downregulated datasets: 0.  

 

Survival by PSMD2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PSMD2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PSMD2 5708 25 0 5
GSE20123 PSMD2 5708 25 0 5
GSE43470 PSMD2 5708 25 0 18
GSE46452 PSMD2 5708 19 1 39
GSE47630 PSMD2 5708 27 2 11
GSE54993 PSMD2 5708 1 19 50
GSE54994 PSMD2 5708 41 0 12
GSE60625 PSMD2 5708 0 6 5
GSE74703 PSMD2 5708 21 0 15
GSE74704 PSMD2 5708 17 0 3
TCGA PSMD2 5708 77 0 19

Total number of gains: 278; Total number of losses: 28; Total Number of normals: 182.  

 

Somatic mutations of PSMD2:

 

Generating mutation plots.

 

Highly correlated genes for PSMD2:

 

Showing top 20/2022 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PSMD2AP2M10.79210912012
PSMD2GMPS0.77965212012
PSMD2EIF4G10.77304712012
PSMD2ECT20.765001908
PSMD2POLR2H0.76140813012
PSMD2ATP13A30.76081110010
PSMD2PSMG30.755836707
PSMD2PARL0.75557513013
PSMD2DNAJB110.749416907
PSMD2ACTL6A0.74822213012
PSMD2RNPS10.743537909
PSMD2LINGO10.742798303
PSMD2MAP3K130.740574707
PSMD2TMEM1890.740473303
PSMD2HAS30.739878504
PSMD2CENPN0.73941910010
PSMD2ALG30.7392613012
PSMD2MCM20.73859311011
PSMD2RFC40.73734413012
PSMD2HJURP0.7359710010

For details and further investigation, click here