| Full name: Rho guanine nucleotide exchange factor 37 | Alias Symbol: FLJ41603 | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 389337 | HGNC ID: HGNC:34430 | Ensembl Gene: ENSG00000183111 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGEF37:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGEF37 | 389337 | 227717_at | -0.3444 | 0.7396 | |
| GSE26886 | ARHGEF37 | 389337 | 227717_at | -0.8472 | 0.0860 | |
| GSE45670 | ARHGEF37 | 389337 | 227717_at | 0.1795 | 0.4815 | |
| GSE53622 | ARHGEF37 | 389337 | 23094 | -0.7889 | 0.0000 | |
| GSE53624 | ARHGEF37 | 389337 | 23094 | -0.8178 | 0.0000 | |
| GSE63941 | ARHGEF37 | 389337 | 227717_at | 0.5713 | 0.6002 | |
| GSE77861 | ARHGEF37 | 389337 | 227717_at | -0.0900 | 0.8710 | |
| GSE97050 | ARHGEF37 | 389337 | A_32_P222695 | -0.2034 | 0.5828 | |
| SRP007169 | ARHGEF37 | 389337 | RNAseq | -0.7320 | 0.2818 | |
| SRP008496 | ARHGEF37 | 389337 | RNAseq | -0.8952 | 0.0263 | |
| SRP064894 | ARHGEF37 | 389337 | RNAseq | -1.0910 | 0.0000 | |
| SRP133303 | ARHGEF37 | 389337 | RNAseq | -0.6084 | 0.0610 | |
| SRP159526 | ARHGEF37 | 389337 | RNAseq | -1.2724 | 0.0022 | |
| SRP193095 | ARHGEF37 | 389337 | RNAseq | -0.2015 | 0.3112 | |
| SRP219564 | ARHGEF37 | 389337 | RNAseq | -1.5867 | 0.0000 | |
| TCGA | ARHGEF37 | 389337 | RNAseq | -0.5703 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ARHGEF37 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGEF37:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGEF37 | 389337 | 1 | 12 | 17 | |
| GSE20123 | ARHGEF37 | 389337 | 1 | 12 | 17 | |
| GSE43470 | ARHGEF37 | 389337 | 1 | 10 | 32 | |
| GSE46452 | ARHGEF37 | 389337 | 0 | 27 | 32 | |
| GSE47630 | ARHGEF37 | 389337 | 0 | 20 | 20 | |
| GSE54993 | ARHGEF37 | 389337 | 9 | 1 | 60 | |
| GSE54994 | ARHGEF37 | 389337 | 2 | 15 | 36 | |
| GSE60625 | ARHGEF37 | 389337 | 0 | 0 | 11 | |
| GSE74703 | ARHGEF37 | 389337 | 1 | 7 | 28 | |
| GSE74704 | ARHGEF37 | 389337 | 1 | 7 | 12 | |
| TCGA | ARHGEF37 | 389337 | 5 | 38 | 53 |
Total number of gains: 21; Total number of losses: 149; Total Number of normals: 318.
Somatic mutations of ARHGEF37:
Generating mutation plots.
Highly correlated genes for ARHGEF37:
Showing top 20/93 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGEF37 | CDK5R1 | 0.6704 | 3 | 0 | 3 |
| ARHGEF37 | P2RX7 | 0.667665 | 3 | 0 | 3 |
| ARHGEF37 | REEP5 | 0.623261 | 4 | 0 | 4 |
| ARHGEF37 | RAD50 | 0.621697 | 5 | 0 | 5 |
| ARHGEF37 | SFN | 0.621449 | 5 | 0 | 4 |
| ARHGEF37 | LTB4R | 0.619038 | 4 | 0 | 3 |
| ARHGEF37 | WDR91 | 0.610714 | 4 | 0 | 3 |
| ARHGEF37 | KRT9 | 0.609689 | 3 | 0 | 3 |
| ARHGEF37 | KCNK10 | 0.601653 | 4 | 0 | 4 |
| ARHGEF37 | GNG4 | 0.598254 | 3 | 0 | 3 |
| ARHGEF37 | HES2 | 0.598253 | 5 | 0 | 4 |
| ARHGEF37 | PDZK1IP1 | 0.592557 | 8 | 0 | 5 |
| ARHGEF37 | THBD | 0.589436 | 3 | 0 | 3 |
| ARHGEF37 | CYB5R1 | 0.585566 | 6 | 0 | 4 |
| ARHGEF37 | DQX1 | 0.585162 | 4 | 0 | 3 |
| ARHGEF37 | S100A12 | 0.584957 | 5 | 0 | 4 |
| ARHGEF37 | IL20RB | 0.581602 | 7 | 0 | 5 |
| ARHGEF37 | CSNK1A1 | 0.581009 | 6 | 0 | 4 |
| ARHGEF37 | PPP2R2C | 0.580269 | 5 | 0 | 3 |
| ARHGEF37 | S100A8 | 0.578242 | 5 | 0 | 4 |
For details and further investigation, click here
