| Full name: thrombospondin type 1 domain containing 1 | Alias Symbol: TMTSP | ||
| Type: protein-coding gene | Cytoband: 13q14.3 | ||
| Entrez ID: 55901 | HGNC ID: HGNC:17754 | Ensembl Gene: ENSG00000136114 | OMIM ID: 616821 |
| Drug and gene relationship at DGIdb | |||
Expression of THSD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | THSD1 | 55901 | 109370 | 0.7091 | 0.0000 | |
| GSE53624 | THSD1 | 55901 | 109370 | 0.8926 | 0.0000 | |
| GSE97050 | THSD1 | 55901 | A_33_P3291092 | 0.4669 | 0.3165 | |
| SRP007169 | THSD1 | 55901 | RNAseq | 1.1577 | 0.1169 | |
| SRP064894 | THSD1 | 55901 | RNAseq | 1.5877 | 0.0000 | |
| SRP133303 | THSD1 | 55901 | RNAseq | 0.8651 | 0.0193 | |
| SRP159526 | THSD1 | 55901 | RNAseq | 0.0060 | 0.9897 | |
| SRP193095 | THSD1 | 55901 | RNAseq | 1.8213 | 0.0000 | |
| SRP219564 | THSD1 | 55901 | RNAseq | 0.3227 | 0.3412 | |
| TCGA | THSD1 | 55901 | RNAseq | 0.7435 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by THSD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THSD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THSD1 | 55901 | 1 | 13 | 16 | |
| GSE20123 | THSD1 | 55901 | 1 | 12 | 17 | |
| GSE43470 | THSD1 | 55901 | 3 | 12 | 28 | |
| GSE46452 | THSD1 | 55901 | 0 | 32 | 27 | |
| GSE47630 | THSD1 | 55901 | 2 | 27 | 11 | |
| GSE54993 | THSD1 | 55901 | 12 | 2 | 56 | |
| GSE54994 | THSD1 | 55901 | 1 | 15 | 37 | |
| GSE60625 | THSD1 | 55901 | 0 | 3 | 8 | |
| GSE74703 | THSD1 | 55901 | 3 | 10 | 23 | |
| GSE74704 | THSD1 | 55901 | 0 | 9 | 11 | |
| TCGA | THSD1 | 55901 | 10 | 35 | 51 |
Total number of gains: 33; Total number of losses: 170; Total Number of normals: 285.
Somatic mutations of THSD1:
Generating mutation plots.
Highly correlated genes for THSD1:
Showing top 20/91 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THSD1 | AFAP1L1 | 0.743284 | 3 | 0 | 3 |
| THSD1 | FLRT2 | 0.72007 | 3 | 0 | 3 |
| THSD1 | JKAMP | 0.71383 | 3 | 0 | 3 |
| THSD1 | KLF7 | 0.708406 | 3 | 0 | 3 |
| THSD1 | FHOD1 | 0.706399 | 3 | 0 | 3 |
| THSD1 | TRIM21 | 0.699444 | 3 | 0 | 3 |
| THSD1 | IKBIP | 0.697258 | 3 | 0 | 3 |
| THSD1 | ARSI | 0.695472 | 3 | 0 | 3 |
| THSD1 | HEATR6 | 0.693699 | 3 | 0 | 3 |
| THSD1 | GUCY1A2 | 0.690153 | 3 | 0 | 3 |
| THSD1 | RIN2 | 0.684731 | 3 | 0 | 3 |
| THSD1 | TDO2 | 0.68447 | 3 | 0 | 3 |
| THSD1 | RAB32 | 0.684464 | 3 | 0 | 3 |
| THSD1 | FGD6 | 0.675825 | 3 | 0 | 3 |
| THSD1 | AGRN | 0.668293 | 3 | 0 | 3 |
| THSD1 | SEC23A | 0.664872 | 3 | 0 | 3 |
| THSD1 | ITGA3 | 0.663009 | 4 | 0 | 4 |
| THSD1 | ZNF469 | 0.662568 | 3 | 0 | 3 |
| THSD1 | GNA12 | 0.661339 | 3 | 0 | 3 |
| THSD1 | AGPS | 0.659181 | 3 | 0 | 3 |
For details and further investigation, click here
