ATP6V0A2

 

Full name: ATPase H+ transporting V0 subunit a2 Alias Symbol: TJ6|a2|TJ6s|TJ6M|ATP6a2|J6B7|ATP6N1D|Vph1|Stv1
Type: protein-coding gene Cytoband: 12q24.31
Entrez ID: 23545 HGNC ID: HGNC:18481 Ensembl Gene: ENSG00000185344 OMIM ID: 611716
Drug and gene relationship at DGIdb

 

ATP6V0A2 involved pathways:

KEGG pathway Description View
hsa05110Vibrio cholerae infection
hsa05120Epithelial cell signaling in Helicobacter pylori infection
hsa05152Tuberculosis

 

Expression of ATP6V0A2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ATP6V0A2 23545 205704_s_at 0.3496 0.4831
GSE20347 ATP6V0A2 23545 205704_s_at 0.6839 0.0006
GSE23400 ATP6V0A2 23545 205704_s_at 0.3516 0.0000
GSE26886 ATP6V0A2 23545 205704_s_at 0.1461 0.5100
GSE29001 ATP6V0A2 23545 205704_s_at 0.7210 0.0005
GSE38129 ATP6V0A2 23545 205704_s_at 0.9276 0.0000
GSE45670 ATP6V0A2 23545 205704_s_at 0.5796 0.0006
GSE63941 ATP6V0A2 23545 205704_s_at 0.3510 0.3781
GSE77861 ATP6V0A2 23545 229572_at 0.2158 0.3712
SRP007169 ATP6V0A2 23545 RNAseq 0.8215 0.0195
SRP008496 ATP6V0A2 23545 RNAseq 0.9888 0.0001
SRP064894 ATP6V0A2 23545 RNAseq 0.1886 0.2047
SRP133303 ATP6V0A2 23545 RNAseq 0.1347 0.3183
SRP159526 ATP6V0A2 23545 RNAseq 0.3944 0.0284
SRP193095 ATP6V0A2 23545 RNAseq 0.0384 0.7556
SRP219564 ATP6V0A2 23545 RNAseq 0.1846 0.4727
TCGA ATP6V0A2 23545 RNAseq -0.2954 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by ATP6V0A2 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of ATP6V0A2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ATP6V0A2 23545 5 5 20
GSE20123 ATP6V0A2 23545 5 5 20
GSE43470 ATP6V0A2 23545 2 0 41
GSE46452 ATP6V0A2 23545 9 1 49
GSE47630 ATP6V0A2 23545 9 3 28
GSE54993 ATP6V0A2 23545 0 5 65
GSE54994 ATP6V0A2 23545 4 8 41
GSE60625 ATP6V0A2 23545 0 0 11
GSE74703 ATP6V0A2 23545 2 0 34
GSE74704 ATP6V0A2 23545 3 3 14
TCGA ATP6V0A2 23545 21 11 64

Total number of gains: 60; Total number of losses: 41; Total Number of normals: 387.  

 

Somatic mutations of ATP6V0A2:

 

Generating mutation plots.

 

Highly correlated genes for ATP6V0A2:

 

Showing top 20/822 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ATP6V0A2MRPL420.750535505
ATP6V0A2CEP550.741584707
ATP6V0A2RAN0.723405505
ATP6V0A2PRC10.708706707
ATP6V0A2PARPBP0.703383404
ATP6V0A2RAD510.689479707
ATP6V0A2CKS20.684904606
ATP6V0A2MELK0.684465707
ATP6V0A2PUS70.683944807
ATP6V0A2RRM20.681706606
ATP6V0A2KNSTRN0.678204303
ATP6V0A2KDELR20.677903303
ATP6V0A2RAD51AP10.675159707
ATP6V0A2NDC10.674475606
ATP6V0A2TRIP130.674467707
ATP6V0A2PUS10.673383706
ATP6V0A2DIABLO0.671564605
ATP6V0A2BUB1B0.671309707
ATP6V0A2KIF230.67079707
ATP6V0A2MTFR20.670492303

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